Occurrence of SARS-CoV-2 in the intraocular milieu.


Journal

Experimental eye research
ISSN: 1096-0007
Titre abrégé: Exp Eye Res
Pays: England
ID NLM: 0370707

Informations de publication

Date de publication:
12 2020
Historique:
received: 14 08 2020
revised: 22 09 2020
accepted: 25 09 2020
pubmed: 30 9 2020
medline: 30 12 2020
entrez: 29 9 2020
Statut: ppublish

Résumé

The purpose of this research is to study the intraocular occurrence of SARS-CoV-2. In postmortem examinations, aqueous humor and the vitreous samples were collected. All individuals were previously positive in nasopharyngeal swabbing and cause of death was respiratory failure due to SARS-CoV-2 infection. Testing was done using quantitative RT-PCR. We included 16 aqueous humor and 16 vitreous samples for PCR testing. None of the results was positive for SARS-CoV-2. Human GAPDH genes to verify the presence of RNA was present in all aqueous humor samples (16/16, 100%) and 15/16 (93.8%) vitreous samples. In conclusion, this case series found no evidence of SARS-CoV-2 in the intraocular milieu.

Identifiants

pubmed: 32991885
pii: S0014-4835(20)30531-5
doi: 10.1016/j.exer.2020.108273
pmc: PMC7521885
pii:
doi:

Substances chimiques

RNA, Viral 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

108273

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

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Auteurs

Wolfgang List (W)

Department of Ophthalmology, Medical University of Graz Auenbruggerplatz 4, 8036, Graz, Austria. Electronic address: wolfgang.list@medunigraz.at.

Peter Regitnig (P)

Diagnostic and Research Institute of Pathology, Medical University of Graz Neue Stiftingtalstraße 6, 8010, Graz, Austria.

Karl Kashofer (K)

Diagnostic and Research Institute of Pathology, Medical University of Graz Neue Stiftingtalstraße 6, 8010, Graz, Austria.

Gregor Gorkiewicz (G)

Diagnostic and Research Institute of Pathology, Medical University of Graz Neue Stiftingtalstraße 6, 8010, Graz, Austria.

Martin Zacharias (M)

Diagnostic and Research Institute of Pathology, Medical University of Graz Neue Stiftingtalstraße 6, 8010, Graz, Austria.

Andreas Wedrich (A)

Department of Ophthalmology, Medical University of Graz Auenbruggerplatz 4, 8036, Graz, Austria.

Laura Posch-Pertl (L)

Department of Ophthalmology, Medical University of Graz Auenbruggerplatz 4, 8036, Graz, Austria.

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Classifications MeSH