Primary Stability of Revision Acetabular Reconstructions Using an Innovative Bone Graft Substitute: A Comparative Biomechanical Study on Cadaveric Pelvises.

biomechanical testing in vitro stability revision hip surgery severe contained acetabular defects synthetic bone graft substitute

Journal

Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929

Informations de publication

Date de publication:
27 Sep 2020
Historique:
received: 05 09 2020
revised: 23 09 2020
accepted: 24 09 2020
entrez: 30 9 2020
pubmed: 1 10 2020
medline: 1 10 2020
Statut: epublish

Résumé

Hip implant failure is mainly due to aseptic loosening of the cotyle and is typically accompanied by defects in the acetabular region. Revision surgery aims to repair such defects before implantation by means of reconstruction materials, whose morselized bone graft represents the gold standard. Due to the limited availability of bone tissue, synthetic substitutes are also used. The aim of this study was to evaluate if a synthetic fully resorbable tri-calcium phosphate-based substitute can provide adequate mechanical stability when employed to restore severe, contained defects, in comparison with morselized bone graft. Five cadaveric pelvises were adopted, one side was reconstructed with morselized bone graft and the other with the synthetic substitute, consisting of dense calcium phosphate granules within a collagen matrix. During the biomechanical test, cyclic load packages of increasing magnitude were applied to each specimen until failure. Bone/implant motions were measured through Digital Image Correlation and were expressed in terms of permanent and inducible translations and rotations. The reconstruction types exhibited a similar behavior, consisting of an initial settling trend followed by failure as bone fracture (i.e., no failure of the reconstruction material). When 2.2 Body Weight was applied, the permanent translations were not significantly different between the two reconstructions (

Identifiants

pubmed: 32992567
pii: ma13194312
doi: 10.3390/ma13194312
pmc: PMC7579522
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Aesculap AG, Research & Development, Tuttlingen, Germany
ID : Research funds to Dept. of Industrial Engineering of University of Bologna
Organisme : Aesculap AG, Research & Development, Tuttlingen, Germany
ID : Research funds to IRCCS Rizzoli Orthopaedic Institute

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Auteurs

Federico Morosato (F)

Department of Industrial Engineering, Alma Mater Studiorum, Università di Bologna, 40131 Bologna, Italy.

Francesco Traina (F)

Chirurgia Protesica, IRCCS Rizzoli Orthopaedic Institute, 40136 Bologna, Italy.
Department of Biomedical and Neuromotor Sciences, Università di Bologna, 40126 Bologna, Italy.

Ronja A Schierjott (RA)

Aesculap AG, Research & Development, Am Aesculap-Platz, 78532 Tuttlingen, Germany.
Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, Campus Grosshadern, Ludwig Maximilian University, 81377 Munich, Germany.

Georg Hettich (G)

Aesculap AG, Research & Development, Am Aesculap-Platz, 78532 Tuttlingen, Germany.

Thomas M Grupp (TM)

Aesculap AG, Research & Development, Am Aesculap-Platz, 78532 Tuttlingen, Germany.
Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, Campus Grosshadern, Ludwig Maximilian University, 81377 Munich, Germany.

Luca Cristofolini (L)

Department of Industrial Engineering, Alma Mater Studiorum, Università di Bologna, 40131 Bologna, Italy.

Classifications MeSH