Evidence of inequitable use of chemotherapy in New Zealand colorectal cancer patients.


Journal

The New Zealand medical journal
ISSN: 1175-8716
Titre abrégé: N Z Med J
Pays: New Zealand
ID NLM: 0401067

Informations de publication

Date de publication:
21 08 2020
Historique:
entrez: 30 9 2020
pubmed: 1 10 2020
medline: 9 10 2020
Statut: epublish

Résumé

To explore variations in the use of and timeliness of chemotherapy in patients diagnosed with colorectal cancer in New Zealand. This study included patients diagnosed with colorectal cancer in New Zealand between 1 January 2006 and 31 December 2016. The first chemotherapy regime was identified from Pharmaceutical Collection dataset. Logistic regression model was used to estimate the adjusted odds ratio of having chemotherapy by subgroup after adjustment for other factors. 27.8% (6,737/24,217) of colon cancer patients and 43.8% (3,582/8,170) of rectal cancer patients received publicly funded chemotherapy. The uptake and timeliness of chemotherapy has been improving over time. Pacific people were the least likely to receive chemotherapy, followed by Māori and Asian. Younger patients, New Zealand European, patients with metastatic disease and patients in the Southern Cancer Network were more likely to have chemotherapy in less than 10 weeks post-diagnosis. Over half of the advanced colorectal cancer patients who did not receive chemotherapy were aged 80+ years or had a short life expectancy. Although the uptake and timeliness of chemotherapy for colorectal cancer has been improving, Māori, Pacific, Asian and older patients were less likely to receive chemotherapy and less likely to receive chemotherapy in a timely manner. There is a variation in use of chemotherapy by Region with patients in the Southern Cancer region appearing to be the most likely to receive chemotherapy and to receive it within a timely period.

Identifiants

pubmed: 32994590

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

15-26

Déclaration de conflit d'intérêts

Dr Lawrenson reports grants from HRC during the conduct of the study; and Board Member of PHARMAC. Member of the Ministry of Health/Cancer Agency's Data Monitoring and Reporting Advisory Group.

Auteurs

Chunhuan Lao (C)

Medical Research Unit, The University of Waikato, Hamilton.

Marion Kuper-Hommel (M)

Medical Research Centre, The University of Waikato, Hamilton.

George Laking (G)

Auckland District Health Board, Auckland.

Lynne Chepulis (L)

Waikato Medical Research Centre, The University of Waikato, Hamilton.

Ross Lawrenson (R)

Medical Research Centre, The University of Waikato, Hamilton.

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Classifications MeSH