Correlation of polyamines, acrolein-conjugated lysine and polyamine metabolic enzyme levels with age in human liver.

Acrolein-conjugated lysine Adenosylmethionine decarboxylase Aging Biochemistry Biomarkers Biomolecules Ornithine decarboxylase Oxidative stress Polyamine Spermine oxidase

Journal

Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 10 06 2020
revised: 21 08 2020
accepted: 18 09 2020
entrez: 30 9 2020
pubmed: 1 10 2020
medline: 1 10 2020
Statut: epublish

Résumé

The polyamines spermidine, spermine and putrescine are essential for normal cellular functions. The contents of polyamines in tissue decreased in aged mice compared to young mice. In this study, the polyamine contents and their metabolic byproduct acrolein-conjugated lysine (

Identifiants

pubmed: 32995657
doi: 10.1016/j.heliyon.2020.e05031
pii: S2405-8440(20)31874-0
pmc: PMC7512001
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e05031

Informations de copyright

© 2020 The Authors. Published by Elsevier Ltd.

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Auteurs

Takeshi Uemura (T)

Amine Pharma Research Institute, 1-8-15 Inohana, Chuo-ku, Chiba 260-0856, Japan.
Department of Forensic Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

Yoshihisa Akasaka (Y)

Department of Forensic Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

Hiroshi Ikegaya (H)

Department of Forensic Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

Classifications MeSH