Therapeutic Anticoagulation Delays Death in COVID-19 Patients: Cross-Sectional Analysis of a Prospective Cohort.

COVID-19 anticoagulation heparin novel coronavirus

Journal

TH open : companion journal to thrombosis and haemostasis
ISSN: 2512-9465
Titre abrégé: TH Open
Pays: Germany
ID NLM: 101715740

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 15 06 2020
accepted: 11 08 2020
entrez: 30 9 2020
pubmed: 1 10 2020
medline: 1 10 2020
Statut: epublish

Résumé

A hypercoagulable state has been described in coronavirus disease 2019 (COVID-19) patients. Others have reported a survival advantage with prophylactic anticoagulation (pAC) and therapeutic anticoagulation (tAC), but these retrospective analyses have important limitations such as confounding by indication. We studied the impact of tAC and pAC compared with no anticoagulation (AC) on time to death in COVID-19. We performed a cross-sectional analysis of 127 deceased COVID-19 patients and compared time to death in those who received tAC (

Identifiants

pubmed: 32995704
doi: 10.1055/s-0040-1716721
pii: 200040
pmc: PMC7519875
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e263-e270

Informations de copyright

The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ).

Déclaration de conflit d'intérêts

Conflict of Interest None declared.

Références

J Thromb Haemost. 2020 Jun;18(6):1517-1519
pubmed: 32294295
J Thromb Haemost. 2020 May;18(5):1020-1022
pubmed: 32239799
J Thromb Haemost. 2020 Jul;18(7):1747-1751
pubmed: 32302448
J Thromb Haemost. 2020 Apr;18(4):844-847
pubmed: 32073213
Am J Hematol. 2020 Jul;95(7):834-847
pubmed: 32282949
J Thromb Haemost. 2020 May;18(5):1023-1026
pubmed: 32338827
Crit Care. 2019 Mar 27;23(1):99
pubmed: 30917856
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Transl Res. 2020 Jun;220:1-13
pubmed: 32299776
J Thromb Haemost. 2020 May;18(5):1094-1099
pubmed: 32220112
JAMA Intern Med. 2020 Jul 1;180(7):934-943
pubmed: 32167524
J Thromb Haemost. 2020 Jul;18(7):1738-1742
pubmed: 32302438
J Thromb Haemost. 2005 Apr;3(4):692-4
pubmed: 15842354
Swiss Med Wkly. 2020 Apr 11;150:w20247
pubmed: 32277760
J Am Coll Cardiol. 2020 Jul 7;76(1):122-124
pubmed: 32387623
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
Lancet. 2020 Feb 29;395(10225):683-684
pubmed: 32122468
Blood Transfus. 2020 May;18(3):167-169
pubmed: 32281926
J Thromb Haemost. 2020 Jul;18(7):1752-1755
pubmed: 32267998
Lancet Respir Med. 2020 Jul;8(7):681-686
pubmed: 32473124
Lancet. 2020 Feb 15;395(10223):473-475
pubmed: 32043983
Thromb Res. 2020 Jul;191:145-147
pubmed: 32291094

Auteurs

Filip Ionescu (F)

Department of Internal Medicine, Beaumont Health System, Royal Oak, Oakland University William Beaumont School of Medicine, Michigan, United States.

Giovi Grasso-Knight (G)

Division of Pulmonary and Critical Care Medicine, Beaumont Health System, Royal Oak, Oakland University William Beaumont School of Medicine, Michigan, United States.

Edward Castillo (E)

Department of Radiation Oncology, Beaumont Health System, Royal Oak, Oakland University William Beaumont School of Medicine, Michigan, United States.
Department of Computational and Applied Mathematics, Rice University, Texas, United States.

Ehsun Naeem (E)

Department of Internal Medicine, Beaumont Health System, Royal Oak, Oakland University William Beaumont School of Medicine, Michigan, United States.

Ioana Petrescu (I)

Department of Internal Medicine, Beaumont Health System, Royal Oak, Oakland University William Beaumont School of Medicine, Michigan, United States.

Zaid Imam (Z)

Department of Internal Medicine, Beaumont Health System, Royal Oak, Oakland University William Beaumont School of Medicine, Michigan, United States.

Vishal K Patel (VK)

Division of Pulmonary and Critical Care Medicine, Beaumont Health System, Royal Oak, Oakland University William Beaumont School of Medicine, Michigan, United States.

Mangala Narasimhan (M)

Division of Pulmonary and Critical Care Medicine, North Well, New York, New York, United States.

Girish B Nair (GB)

Division of Pulmonary and Critical Care Medicine, Beaumont Health System, Royal Oak, Oakland University William Beaumont School of Medicine, Michigan, United States.

Classifications MeSH