Toxic effect of some heavy metals on hematology and histopathology of major carp (Catla catla).
Alterations
Degeneration
Fish
Heavy metals
Hematology
Histopathology
Journal
Environmental science and pollution research international
ISSN: 1614-7499
Titre abrégé: Environ Sci Pollut Res Int
Pays: Germany
ID NLM: 9441769
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
12
05
2020
accepted:
21
09
2020
pubmed:
1
10
2020
medline:
30
1
2021
entrez:
30
9
2020
Statut:
ppublish
Résumé
The current study was conducted to assess the hematological and histopathological changes in major carp (Catla catla) exposed to different concentrations of copper (Cu) and cadmium (Cd). For this purpose, Catla catla fish, weighing approximately 230-235 g, were randomly divided into four groups and then exposed to acute doses of Cu (1.25 ppm), Cd (4.5 ppm), and their mixture (2.25 ppm) for 96 h and then 20, 30, and 40% respectively for a period of 30 days. Results showed that red blood cells (RBCs), hemoglobin (Hb), hematocrit (Hct), lymphocyte, and monocyte decreased significantly, while the total white blood cell count and neutrophil population significantly increased in experimental groups as compared with the control one. Histopathological examination of liver tissues showed karyorrhexis, hepatic cells degeneration, congestion, and hemorrhages. Microscopic analysis of gills' sections revealed lamellar atrophy, telangiectasia, and necrosis of lamellar epithelial cells. In the kidneys, different histopathological ailments like atrophy of glomeruli, necrosis of renal tubular cells, increased urinary spaces, degeneration of renal tubules, and melanomacrophage aggregates were observed, while in the intestine, atrophy of villi, sloughing of epithelial villi, and congestion were seen after 30 days of exposure. In conclusion, the study indicates that exposure to Cu and Cd for longer period of time causes adverse hematological and histopathological changes in Catla catla fish.
Identifiants
pubmed: 32997242
doi: 10.1007/s11356-020-10980-0
pii: 10.1007/s11356-020-10980-0
doi:
Substances chimiques
Metals, Heavy
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
6533-6539Références
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