The degradation behavior of calcium-rich hydroxyapatite foams in vitro.


Journal

Journal of biomedical materials research. Part A
ISSN: 1552-4965
Titre abrégé: J Biomed Mater Res A
Pays: United States
ID NLM: 101234237

Informations de publication

Date de publication:
06 2021
Historique:
revised: 15 06 2020
received: 27 08 2019
accepted: 23 06 2020
pubmed: 1 10 2020
medline: 1 1 2022
entrez: 30 9 2020
Statut: ppublish

Résumé

Hydroxyapatite (HA) is a well-known regenerative biomaterial. However, the slow degradation rate of HA is still an obstacle in clinical applications. In this study, we concentrated on investigating the degradation behavior of the calcium-rich HA foams, which had a demonstrated effect on blood differentiation in previous studies. The HA foams were processed by an emulsion method and were infiltrated with calcium nitrate to create a calcium carbonate second phase, heterogeneously distributed on and under the surface of the foam. During the 28-day solubility test, the calcium carbonate phase contributed to enhanced Ca

Identifiants

pubmed: 32997885
doi: 10.1002/jbm.a.37077
doi:

Substances chimiques

Biocompatible Materials 0
Bone Substitutes 0
Calcium Compounds 0
Emulsions 0
Nitrates 0
Durapatite 91D9GV0Z28
Calcium Carbonate H0G9379FGK
calcium nitrate NF52F38N1N
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

859-868

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL108631
Pays : United States

Informations de copyright

© 2020 Wiley Periodicals LLC.

Références

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Auteurs

Qinghao Zhang (Q)

Material Science and Engineering School, East China University of Science and Technology, Shanghai, China.
Department of Mechanical Engineering and Materials Science, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Wenfu Wang (W)

Department of Mechanical Engineering and Materials Science, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Eva Schmelzer (E)

Department of Surgery, McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Jörg Gerlach (J)

Department of Surgery, McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Changsheng Liu (C)

Material Science and Engineering School, East China University of Science and Technology, Shanghai, China.

Ian Nettleship (I)

Department of Mechanical Engineering and Materials Science, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Department of Surgery, McGowan Institute of Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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Classifications MeSH