Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment and dementia.
Aging
Cognitive function
Dementia
Neurodegeneration geroscience
Neurovascular coupling
Time restricted feeding
Journal
Ageing research reviews
ISSN: 1872-9649
Titre abrégé: Ageing Res Rev
Pays: England
ID NLM: 101128963
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
13
07
2020
revised:
04
09
2020
accepted:
21
09
2020
pubmed:
1
10
2020
medline:
31
12
2020
entrez:
30
9
2020
Statut:
ppublish
Résumé
Aging is the most significant risk factor for vascular cognitive impairment (VCI), and the number of individuals affected by VCI is expected to exponentially increase in the upcoming decades. Yet, there are no current preventative or therapeutic treatments available against the development and progression of VCI. Therefore, there is a pressing need to better understand the pathophysiology underlying these conditions, for the development of novel tools and interventions to improve cerebrovascular health and delay the onset of VCI. There is strong epidemiological and experimental evidence that lifestyle factors, including nutrition and dietary habits, significantly affect cerebrovascular health and thereby influence the pathogenesis of VCI. Here, recent evidence is presented discussing the effects of lifestyle interventions against age-related diseases which in turn, inspired novel research aimed at investigating the possible beneficial effects of dietary interventions for the prevention of cognitive decline in older adults.
Identifiants
pubmed: 32998063
pii: S1568-1637(20)30324-X
doi: 10.1016/j.arr.2020.101189
pmc: PMC7710623
mid: NIHMS1632969
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
101189Subventions
Organisme : NIGMS NIH HHS
ID : P20 GM125528
Pays : United States
Organisme : NIA NIH HHS
ID : T32 AG052363
Pays : United States
Informations de copyright
Published by Elsevier B.V.
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