Is DAT imaging abnormality in normal pressure hydrocephalus always suggestive of degeneration?


Journal

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 13 01 2020
accepted: 19 09 2020
pubmed: 2 10 2020
medline: 15 5 2021
entrez: 1 10 2020
Statut: ppublish

Résumé

Idiopathic normal pressure hydrocephalus (iNPH) is a debated entity with controversial pathogenesis, diagnostic criteria, and predictors of response after ventriculoperitoneal shunt (VPS). Parkinsonian signs are frequently reported in the clinical picture, sometimes due to the coexistence of an underlying neurodegenerative parkinsonism and sometimes in the absence thereof. To distinguish these two scenarios is crucial, since they may carry different long-term response to CSF drainage.

Identifiants

pubmed: 33000331
doi: 10.1007/s10072-020-04743-5
pii: 10.1007/s10072-020-04743-5
doi:

Substances chimiques

Dopamine Plasma Membrane Transport Proteins 0
Tropanes 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

723-726

Subventions

Organisme : Ministero della Salute (IT)
ID : RF- 2013-02355908

Références

Relkin N, Marmarou A, Klinge P, Bergsneider M, Black PM (2005) Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery 57(3 Suppl):S4–S16 discussion ii-v
pubmed: 16160425
Mori E, Ishikawa M, Kato T, Kazui H, Miyake H, Miyajima M et al (2012) Guidelines for management of idiopathic normal pressure hydrocephalus: second edition. Neurol Med Chir 52(11):775–809
doi: 10.2176/nmc.52.775
Espay AJ, Da Prat GA, Dwivedi AK, Rodriguez-Porcel F, Vaughan JE, Rosso M et al (2017) Deconstructing normal pressure hydrocephalus: ventriculomegaly as early sign of neurodegeneration. Ann Neurol 82(4):503–513
doi: 10.1002/ana.25046
Curran T, Lang AE (1994) Parkinsonian syndromes associated with hydrocephalus: case reports, a review of the literature, and pathophysiological hypotheses. Mov Disord 9:508–520
doi: 10.1002/mds.870090503
Broggi M, Redaelli V, Tringali G, Restelli F, Romito L, Schiavolin S, Tagliavini F, Broggi G (2016) Normal pressure hydrocephalus and parkinsonism: preliminary data on neurosurgical and neurological treatment. World Neurosurg 90:348–356
doi: 10.1016/j.wneu.2016.03.004
Krauss JK, Regel JP, Droste DW, Orszagh M, Borremans JJ, Vach W (1997) Movement disorders in adult hydrocephalus. Mov Disord 12:53–60
doi: 10.1002/mds.870120110
Allali G, Garibotto V, Mainta IC, Nicastro N, Assal F (2018) Dopaminergic imaging separates normal pressure hydrocephalus from its mimics. J Neurol 265:2434–2441
doi: 10.1007/s00415-018-9029-y
Cosottini M, Frosini D, Pesaresi I, Donatelli G, Cecchi P, Costagli M, Biagi L, Ceravolo R, Bonuccelli U, Tosetti M (2015) Comparison of 3T and 7T susceptibility-weighted angiography of the substantia nigra in diagnosing Parkinson disease. AJNR Am J Neuroradiol 36:461–466
doi: 10.3174/ajnr.A4158
Ouchi Y, Nakayama T, Kanno T, Yoshikawa E, Shinke T, Torizuka T (2007) In vivo presynaptic and postsynaptic striatal dopamine functions in idiopathic normal pressure hydrocephalus. J Cereb Blood Flow Metab 27(4):803–810
doi: 10.1038/sj.jcbfm.9600389
Nakayama T, Ouchi Y, Yoshikawa E, Sugihara G, Torizuka T, Tanaka K (2007) Striatal D2 receptor availability after shunting in idiopathic normal pressure hydrocephalus. J Nucl Med 48(12):1981–1986
doi: 10.2967/jnumed.107.045310

Auteurs

Claudia Del Gamba (C)

Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy.

Antonino Bruno (A)

Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy.

Daniela Frosini (D)

Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy.

Duccio Volterrani (D)

Department of Translational Research and of New Surgical and Medical Technologies, Nuclear Medicine Unit, University of Pisa, Pisa, Italy.

Gianmichele Migaleddu (G)

Department of Translational Research and of New Surgical and Medical Technologies, Neuroradiology Unit, University of Pisa, Pisa, Italy.

Nicola Benedetto (N)

Department of Neurosurgery, University of Pisa, Pisa, Italy.

Paolo Perrini (P)

Department of Neurosurgery, University of Pisa, Pisa, Italy.

Claudio Pacchetti (C)

Parkinson's Disease and Movement Disorders Unit, IRCCS Mondino Foundation, Pavia, Italy.

Mirco Cosottini (M)

Department of Translational Research and of New Surgical and Medical Technologies, Neuroradiology Unit, University of Pisa, Pisa, Italy.

Ubaldo Bonuccelli (U)

Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy.

Roberto Ceravolo (R)

Department of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy. robertoceravolo66@gmail.com.

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Classifications MeSH