The use of positive end expiratory pressure in patients affected by COVID-19: Time to reconsider the relation between morphology and physiology.


Journal

Best practice & research. Clinical anaesthesiology
ISSN: 1878-1608
Titre abrégé: Best Pract Res Clin Anaesthesiol
Pays: Netherlands
ID NLM: 101121446

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 14 07 2020
accepted: 15 07 2020
entrez: 2 10 2020
pubmed: 3 10 2020
medline: 21 10 2020
Statut: ppublish

Résumé

Coronavirus disease 2019 (COVID-19) is a new disease with different phases that can be catastrophic for subpopulations of patients with cardiovascular and pulmonary disease states at baseline. Appreciation for these different phases and treatment modalities, including manipulation of ventilatory settings and therapeutics, has made it a less lethal disease than when it emerged earlier this year. Different aspects of the disease are still largely unknown. However, laboratory investigation and clinical course of the COVID-19 show that this new disease is not a typical acute respiratory distress syndrome process, especially during the first phase. For this reason, the best strategy to be applied is to treat differently the single phases and to support the single functions of the failing organs as they appear.

Identifiants

pubmed: 33004167
pii: S1521-6896(20)30062-8
doi: 10.1016/j.bpa.2020.07.007
pmc: PMC7367781
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

561-567

Informations de copyright

Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest Dr Kaye serves on the Speakers Bureau for Merck, Inc.

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Auteurs

Gaetano Perchiazzi (G)

Hedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Central Intensive Care Unit, Department of Anesthesia, Operation and Intensive Care, Uppsala University Hospital, Uppsala, Sweden. Electronic address: gaetano.perchiazzi@surgsci.uu.se.

Mariangela Pellegrini (M)

Hedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Central Intensive Care Unit, Department of Anesthesia, Operation and Intensive Care, Uppsala University Hospital, Uppsala, Sweden.

Elena Chiodaroli (E)

Hedenstierna Laboratory, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.

Ivan Urits (I)

Beth Israel Deaconess Medical Center, Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA, USA.

Alan D Kaye (AD)

Department of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, LA, USA.

Omar Viswanath (O)

Department of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, LA, USA; Valley Pain Consultants - Envision Physician Services, Phoenix, AZ, USA; University of Arizona College of Medicine-Phoenix, Department of Anesthesiology Phoenix, AZ, USA; Creighton University School of Medicine, Department of Anesthesiology, Omaha, NE, USA.

Giustino Varrassi (G)

Paolo Procacci Foundation, Roma, Italy.

Filomena Puntillo (F)

Department of Interdisciplinary Medicine (DIM), University of Bari, Italy.

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