Idelalisib treatment prior to allogeneic stem cell transplantation for patients with chronic lymphocytic leukemia: a report from the EBMT chronic malignancies working party.
Journal
Bone marrow transplantation
ISSN: 1476-5365
Titre abrégé: Bone Marrow Transplant
Pays: England
ID NLM: 8702459
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
25
03
2020
accepted:
18
09
2020
revised:
15
09
2020
pubmed:
3
10
2020
medline:
6
7
2021
entrez:
2
10
2020
Statut:
ppublish
Résumé
No studies have been reported so far on bridging treatment with idelalisib for patients with chronic lymphocytic leukemia (CLL) prior to allogeneic hematopoietic cell transplantation (alloHCT). To study potential carry-over effects of idelalisib and to assess the impact of pathway-inhibitor (PI) failure we performed a retrospective EBMT registry-based study. Patients with CLL who had a history of idelalisib treatment and received a first alloHCT between 2015 and 2017 were eligible. Data on 72 patients (median age 58 years) were analyzed. Forty percent of patients had TP53
Identifiants
pubmed: 33004942
doi: 10.1038/s41409-020-01069-w
pii: 10.1038/s41409-020-01069-w
pmc: PMC8589680
doi:
Substances chimiques
Purines
0
Quinazolinones
0
idelalisib
YG57I8T5M0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
605-613Commentaires et corrections
Type : ErratumIn
Références
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