Dose response of a novel exogenous ketone supplement on physiological, perceptual and performance parameters.

Beta hydroxybutyrate Cognition Ketogenic Ketone bodies Medium chain triglycerides Performance

Journal

Nutrition & metabolism
ISSN: 1743-7075
Titre abrégé: Nutr Metab (Lond)
Pays: England
ID NLM: 101231644

Informations de publication

Date de publication:
2020
Historique:
received: 09 07 2020
accepted: 04 09 2020
entrez: 2 10 2020
pubmed: 3 10 2020
medline: 3 10 2020
Statut: epublish

Résumé

Interest into the health, disease, and performance impact of exogenous ketone bodies has rapidly expanded due to their multifaceted physiological and signaling properties but limiting our understanding is the isolated analyses of individual types and dose/dosing protocols. Thirteen recreational male distance runners (24.8 ± 9.6 years, 72.5 ± 8.3 kg, VO KS significantly increased Novel βHB + MCT formulation had a dosing effect on

Sections du résumé

BACKGROUND BACKGROUND
Interest into the health, disease, and performance impact of exogenous ketone bodies has rapidly expanded due to their multifaceted physiological and signaling properties but limiting our understanding is the isolated analyses of individual types and dose/dosing protocols.
METHODS METHODS
Thirteen recreational male distance runners (24.8 ± 9.6 years, 72.5 ± 8.3 kg, VO
RESULTS RESULTS
KS significantly increased
CONCLUSION CONCLUSIONS
Novel βHB + MCT formulation had a dosing effect on

Identifiants

pubmed: 33005207
doi: 10.1186/s12986-020-00497-1
pii: 497
pmc: PMC7523040
doi:

Types de publication

Journal Article

Langues

eng

Pagination

81

Informations de copyright

© The Author(s) 2020.

Déclaration de conflit d'intérêts

Competing interestsPJP, CQR, DLA, DWJ, KGA, JLH, ELE, SRH, TJR, ADA, GLW, JDB declare no competing interest. DD is an inventor on a patent entitled “Composition and Methods of Elevating and Sustaining Ketosis” USPTO# 20170266148. This invention was made with government support under Grant # N00014-13-1-0062 awarded by the Department of Defense, Office of Naval Research. APK and DPD are inventors on provisional patents “Compositions and Methods for Weight Loss Maintenance” and “Prevention of Muscle Wasting with Ketone Supplementation” using technologies dissimilar to the ketones formulation used in this manuscript. At the time of this publication, provision patents were still under review. However, should provisional patents become accepted and royalties ever accrue, APK and DPD will receive a share under the terms prescribed by the University of South Florida. DPD is an owner of Ketone Technologies LLC and has served as a consultant and conference speaker.

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Auteurs

Philip J Prins (PJ)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Dominic P D'Agostino (DP)

Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL USA.
Human Health, Resilience, and Performance, Institute of Human and Machine Cognition, Pensacola, FL USA.

Christopher Q Rogers (CQ)

Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL USA.

Dana L Ault (DL)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Gary L Welton (GL)

Department of Psychology, Grove City College, Grove City, PA USA.

Dalton W Jones (DW)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Samuel R Henson (SR)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Tyler J Rothfuss (TJ)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Kylie G Aiken (KG)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Jantzen L Hose (JL)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Emilia L England (EL)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Adam D Atwell (AD)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Jeffrey D Buxton (JD)

Department of Exercise Science, Grove City College, 100 Campus Drive, Grove City, PA 16127 USA.

Andrew P Koutnik (AP)

Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL USA.
Human Health, Resilience, and Performance, Institute of Human and Machine Cognition, Pensacola, FL USA.

Classifications MeSH