Tunable Harmonic Flow Patterns in Microfluidic Systems through Simple Tube Oscillation.
dynamic flow patterns
microfluidics
tube oscillation
Journal
Small (Weinheim an der Bergstrasse, Germany)
ISSN: 1613-6829
Titre abrégé: Small
Pays: Germany
ID NLM: 101235338
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
13
06
2020
revised:
29
07
2020
pubmed:
3
10
2020
medline:
3
10
2020
entrez:
2
10
2020
Statut:
ppublish
Résumé
Generation of tunable harmonic flows at low cost in microfluidic systems is a persistent and significant obstacle to this field, substantially limiting its potential to address major scientific questions and applications. This work introduces a simple and elegant way to overcome this obstacle. Harmonic flow patterns can be generated in microfluidic structures by simply oscillating the inlet tubes. Complex rib and vortex patterns can be dynamically modulated by changing the frequency and magnitude of tube oscillation and the viscosity of liquid. Highly complex rib patterns and synchronous vortices can be generated in serially connected microfluidic chambers. Similar dynamic patterns can be generated using whole or diluted blood samples without damaging the sample. This method offers unique opportunities for studying complex fluids and soft materials, chemical synthesis of various compounds, and mimicking harmonic flows in biological systems using compact, tunable, and low-cost devices.
Identifiants
pubmed: 33006247
doi: 10.1002/smll.202003612
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2003612Informations de copyright
© 2020 Wiley-VCH GmbH.
Références
G. M. Whitesides, Nature 2006, 442, 368.
Y. Yang, Y. Chen, H. Tang, N. Zong, X. Jiang, Small Methods 2020, 4, 1900451.
H. A. Stone, S. Kim, AIChE J. 2001, 47, 1250.
T. M. Squires, S. R. Quake, Rev. Mod. Phys. 2005, 77, 977.
S. Granick, Y. Zhu, H. Lee, Nat. Mater. 2003, 2, 221.
M. Mitov, Soft Matter 2017, 13, 4176.
B. Keshavarz, E. C. Houze, J. R. Moore, M. R. Koerner, G. H. McKinley, Phys. Rev. Fluids 2020, 5, 033601.
F. Bian, L. Sun, L. Cai, Y. Wang, Y. Wang, Y. Zhao, Small 2020, 16, 1903931.
C. C. Hopkins, S. J. Haward, A. Q. Shen, Small 2020, 16, 1903872.
M. Asghari, X. Cao, B. Mateescu, D. van Leeuwen, M. K. Aslan, S. Stavrakis, A. J. deMello, ACS Nano 2020, 14, 422.
K. S. Elvira, X. C. i Solvas, R. C. R. Wootton, A. J. deMello, Nat. Chem. 2013, 5, 905.
Y. Liu, X. Jiang, Lab Chip 2017, 17, 3960.
F. Eduati, R. Utharala, D. Madhavan, U. P. Neumann, T. Longerich, T. Cramer, J. Saez-Rodriguez, C. A. Merten, Nat. Commun. 2018, 9, 2434.
Z. Liu, F. Fontana, A. Python, J. T. Hirvonen, H. A. Santos, Small 2020, 16, 1904673.
C. Hahn, M. A. Schwartz, Nat. Rev. Mol. Cell Biol. 2009, 10, 53.
J.-J. Chiu, S. Chien, Physiol. Rev. 2011, 91, 327.
S. Baratchi, K. Khoshmanesh, O. L. Woodman, S. Potocnik, K. Peter, P. McIntyre, Trends Mol. Med. 2017, 23, 850.
B. Dincau, E. Dressaire, A. Sauret, Small 2020, 16, 1904032.
S. Baratchi, M. T. K. Zaldivia, M. Wallert, J. Loseff-Silver, S. Al-Aryahi, J. Zamani, P. Thurgood, A. Salim, N. M. Htun, D. Stub, P. Vahidi, S. J. Duffy, A. Walton, T. H. Nguyen, A. Jaworowski, K. Khoshmanesh, K. Peter, Circulation, https://doi.org/10.1161/CIRCULATIONAHA.120.045536.
H. Ahmed, S. Ramesan, L. Lee, A. R. Rezk, L. Y. Yeo, Small 2020, 16, 1903605.
H. Amini, W. Lee, D. Di Carlo, Lab Chip 2014, 14, 2739.
J. Zhang, S. Yan, D. Yuan, G. Alici, N.-T. Nguyen, M. E. Warkiani, W. Li, Lab Chip 2016, 16, 10.
A. D. Stroock, S. K. W. Dertinger, A. Ajdari, I. Mezić, H. A. Stone, G. M. Whitesides, Science 2002, 295, 647.
A. P. Sudarsan, V. M. Ugaz, Proc. Natl. Acad. Sci. USA 2006, 103, 7228.
M. E. Warkiani, A. K. P. Tay, G. Guan, J. Han, Sci. Rep. 2015, 5, 11018.
A. J. Mach, J. H. Kim, A. Arshi, S. C. Hur, D. Di Carlo, Lab Chip 2011, 11, 2827.
E. Sollier, D. E. Go, J. Che, D. R. Gossett, S. O'Byrne, W. M. Weaver, N. Kummer, M. Rettig, J. Goldman, N. Nickols, S. McCloskey, R. P. Kulkarni, D. Di Carlo, Lab Chip 2014, 14, 63.
P. Thurgood, S. A. Suarez, S. Chen, C. Gilliam, E. Pirogova, A. R. Jex, S. Baratchi, K. Khoshmanesh, Lab Chip 2019, 19, 2885.
N. Nguyen, P. Thurgood, A. Arash, E. Pirogova, S. Baratchi, K. Khoshmanesh, Adv. Funct. Mater. 2019, 29, 1901998.
A. K. Agarwal, S. S. Sridharamurthy, D. J. Beebe, J. Hongrui, J. Microelectromech. Syst. 2005, 14, 1409.
K. S. Ryu, K. Shaikh, E. Goluch, Z. Fan, C. Liu, Lab Chip 2004, 4, 608.
S. Vedel, L. H. Olesen, H. Bruus, J. Micromech. Microeng. 2010, 20, 035026.
X. Zhou, X. Zhou, B. Zheng, Biomicrofluidics 2013, 7, 054116.
K. Khoshmanesh, A. Almansouri, H. Albloushi, P. Yi, R. Soffe, K. Kalantar-zadeh, Sci. Rep. 2015, 5, 9942.
S.-J. Kim, R. Yokokawa, S. Takayama, Lab Chip 2013, 13, 1644.
R. Xu, H. Xin, B. Li, AIP Adv. 2013, 3, 052120.
C. Chen, S. P. Zhang, Z. Mao, N. Nama, Y. Gu, P.-H. Huang, Y. Jing, X. Guo, F. Costanzo, T. J. Huang, Lab Chip 2018, 18, 3645.
D. J. Collins, B. L. Khoo, Z. Ma, A. Winkler, R. Weser, H. Schmidt, J. Han, Y. Ai, Lab Chip 2017, 17, 1769.
M. Z. Bazant, in Encyclopedia of Microfluidics and Nanofluidics (Ed: D. Li), Springer New York, New York 2015, pp. 2416-2426.
S. T. Chang, E. Beaumont, D. N. Petsev, O. D. Velev, Lab Chip 2008, 8, 117.
S.-Y. Tang, K. Khoshmanesh, V. Sivan, P. Petersen, A. P. O'Mullane, D. Abbott, A. Mitchell, K. Kalantar-zadeh, Proc. Natl. Acad. Sci. USA 2014, 111, 3304.
S.-Y. Tang, V. Sivan, P. Petersen, W. Zhang, P. D. Morrison, K. Kalantar-zadeh, A. Mitchell, K. Khoshmanesh, Adv. Funct. Mater. 2014, 24, 5851.
M. Boyd-Moss, S. Baratchi, M. Di Venere, K. Khoshmanesh, Lab Chip 2016, 16, 3177.
J. Harris, G. Peev, W. L. Wilkinson, J. Phys. E: Sci. Instrum. 1969, 2, 913.
S. I. Sergeev, Fluid Dyn. 1967, 1, 121.
M. Teufel, D. Trimis, A. Lohmüller, Y. Takeda, F. Durst, Flow Meas. Instrum. 1992, 3, 95.
M. Amaratunga, H. A. Rabenjafimanantsoa, R. W. Time, Flow Meas. Instrum. 2019, 70, 101628.
R. J. Whittaker, M. Heil, S. L. Waters, Philos. Trans. R Soc., A 2011, 369, 2989.
N. Zhuang, S. Tan, H. Yuan, Exp. Therm. Fluid Sci. 2016, 76, 352.
Y. Su, J. H. Davidson, F. Kulacki, World Acad. Sci. Eng. Technol. 2011, 81, 653.
M. Ohmi, M. Iguchi, K. Kakehashi, T. Masuda, Bull. JSME 1982, 25, 365.
K. H. Ahn, M. B. Ibrahim, Int. J. Heat Fluid Flow 1992, 13, 340.
R. Trip, D. J. Kuik, J. Westerweel, C. Poelma, Phys. Fluids 2012, 24, 014103.
F. P. Incropera, D. P. DeWitt, Fundamentals of Heat and Mass Transfer, Wiley, New York 2002.
M. J. Fuerstman, A. Lai, M. E. Thurlow, S. S. Shevkoplyas, H. A. Stone, G. M. Whitesides, Lab Chip 2007, 7, 1479.
M. Mohammed, P. Thurgood, C. Gilliam, N. Nguyen, E. Pirogova, K. Peter, K. Khoshmanesh, S. Baratchi, Anal. Chem. 2019, 91, 12077.
Y.-S. Lee, N. Bhattacharjee, A. Folch, Lab Chip 2018, 18, 1207.
O. Cybulski, P. Garstecki, B. A. Grzybowski, Nat. Phys. 2019, 15, 706.
M. Heuberger, L. Gottardo, M. Dressler, R. Hufenus, Microfluid. Nanofluid. 2015, 19, 653.
J. Lee, M. A. Burns, Small 2018, 14, 1702724.
A. T. Ciftlik, M. Ettori, M. A. M. Gijs, Small 2013, 9, 2764.
S. Nayak, N. R. Blumenfeld, T. Laksanasopin, S. K. Sia, Anal. Chem. 2017, 89, 102.
D. E. Ingber, Development 2018, 145, dev156125.
Y. Deng, S. P. Davis, F. Yang, K. S. Paulsen, M. Kumar, R. S. DeVaux, X. Wang, D. S. Conklin, A. Oberai, J. I. Herschkowitz, A. J. Chung, Small 2017, 13, 1700705.
A. Liu, T. Yu, K. Young, N. Stone, S. Hanasoge, T. J. Kirby, V. Varadarajan, N. Colonna, J. Liu, A. Raj, J. Lammerding, A. Alexeev, T. Sulchek, Small 2020, 16, 1903857.
F. Tovar-Lopez, P. Thurgood, C. Gilliam, N. Nguyen, E. Pirogova, K. Khoshmanesh, S. Baratchi, Front. Bioeng. Biotechnol. 2019, 7, 81.
J. Blazek, Computational Fluid Dynamics: Principles and Applications, Elsevier Science, Amsterdam 2005.