Room-temperature neutron and X-ray data collection of 3CL M
Betacoronavirus
/ chemistry
COVID-19
Catalytic Domain
Coronavirus 3C Proteases
Coronavirus Infections
/ virology
Crystallography, X-Ray
Cysteine Endopeptidases
/ chemistry
Humans
Models, Molecular
Neutron Diffraction
Pandemics
Pneumonia, Viral
/ virology
Protein Conformation
Recombinant Proteins
/ chemistry
SARS-CoV-2
Temperature
Viral Nonstructural Proteins
/ chemistry
3CL Mpro
SARS-CoV-2
X-ray diffraction
neutron diffraction
Journal
Acta crystallographica. Section F, Structural biology communications
ISSN: 2053-230X
Titre abrégé: Acta Crystallogr F Struct Biol Commun
Pays: United States
ID NLM: 101620319
Informations de publication
Date de publication:
01 Oct 2020
01 Oct 2020
Historique:
received:
03
08
2020
accepted:
27
08
2020
entrez:
2
10
2020
pubmed:
3
10
2020
medline:
21
10
2020
Statut:
ppublish
Résumé
The replication of SARS-CoV-2 produces two large polyproteins, pp1a and pp1ab, that are inactive until cleavage by the viral chymotrypsin-like cysteine protease enzyme (3CL M
Identifiants
pubmed: 33006576
pii: S2053230X20011814
doi: 10.1107/S2053230X20011814
pmc: PMC7531248
doi:
Substances chimiques
Recombinant Proteins
0
Viral Nonstructural Proteins
0
Cysteine Endopeptidases
EC 3.4.22.-
Coronavirus 3C Proteases
EC 3.4.22.28
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
483-487Informations de copyright
open access.
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