Ellagic acid prevents kidney injury and oxidative damage via regulation of Nrf-2/NF-κB signaling in carbon tetrachloride induced rats.
COX-2
Carbon tetrachloride
Ellagic acid
Kidney
NF-κB
Nrf-2
VEGF
Journal
Molecular biology reports
ISSN: 1573-4978
Titre abrégé: Mol Biol Rep
Pays: Netherlands
ID NLM: 0403234
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
18
06
2020
accepted:
28
09
2020
pubmed:
3
10
2020
medline:
20
5
2021
entrez:
2
10
2020
Statut:
ppublish
Résumé
Phytochemicals, bioactive food compounds, found in plants have been described as protective agents against renal injury. This work was planned to evaluate the effects of EA on anti-oxidative and anti-inflammation pathways in kidney damage induced with carbon tetrachloride. In this study, experimental animals (n = 36, 8 weeks old rats) were divided into 4 groups as follows: 1) Control group 2) EA group (10 mg/kg body weight) 3) CCl
Identifiants
pubmed: 33006714
doi: 10.1007/s11033-020-05873-x
pii: 10.1007/s11033-020-05873-x
doi:
Substances chimiques
NF-E2-Related Factor 2
0
NF-kappa B
0
Ellagic Acid
19YRN3ZS9P
Carbon Tetrachloride
CL2T97X0V0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
7959-7970Subventions
Organisme : Firat University Scientific Research Projects Management Unit
ID : FF.16.42