Transcriptome Profiling Analyses in Psoriasis: A Dynamic Contribution of Keratinocytes to the Pathogenesis.
RNA-seq
gene expression
keratinocytes
microarray
psoriasis
skin
transcriptome
Journal
Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097
Informations de publication
Date de publication:
30 09 2020
30 09 2020
Historique:
received:
09
09
2020
revised:
28
09
2020
accepted:
29
09
2020
entrez:
3
10
2020
pubmed:
4
10
2020
medline:
20
7
2021
Statut:
epublish
Résumé
Psoriasis is an immune-mediated inflammatory skin disease with a complex etiology involving environmental and genetic factors. A better insight into related genomic alteration helps design precise therapies leading to better treatment outcome. Gene expression in psoriasis can provide relevant information about the altered expression of mRNA transcripts, thus giving new insights into the disease onset. Techniques for transcriptome analyses, such as microarray and RNA sequencing (RNA-seq), are relevant tools for the discovery of new biomarkers as well as new therapeutic targets. This review summarizes the findings related to the contribution of keratinocytes in the pathogenesis of psoriasis by an in-depth review of studies that have examined psoriatic transcriptomes in the past years. It also provides valuable information on reconstructed 3D psoriatic skin models using cells isolated from psoriatic patients for transcriptomic studies.
Identifiants
pubmed: 33007857
pii: genes11101155
doi: 10.3390/genes11101155
pmc: PMC7600703
pii:
doi:
Substances chimiques
Lipids
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : CIHR
ID : MOP-311262
Pays : Canada
Références
Clin Dev Immunol. 2013;2013:482691
pubmed: 23690822
Arch Dermatol. 1974 Feb;109(2):207-11
pubmed: 4814926
Nature. 2007 Oct 4;449(7162):564-9
pubmed: 17873860
Nat Commun. 2015 Apr 23;6:6916
pubmed: 25903422
Biochem Pharmacol. 2009 Mar 15;77(6):937-46
pubmed: 19022225
Nat Genet. 2009 Feb;41(2):199-204
pubmed: 19169254
J Invest Dermatol. 2018 Jun;138(6):1311-1317
pubmed: 29317264
Brief Bioinform. 2019 Jul 19;20(4):1384-1394
pubmed: 29394315
Lancet. 2007 Jul 21;370(9583):263-271
pubmed: 17658397
J Invest Dermatol. 2019 Jan;139(1):135-145
pubmed: 30118730
Ann Rheum Dis. 2005 Mar;64 Suppl 2:ii30-6
pubmed: 15708932
J Invest Dermatol. 2018 Jul;138(7):1518-1528
pubmed: 29454560
Genome Med. 2009 Jul 22;1(7):72
pubmed: 19638187
Cells. 2019 Sep 25;8(10):
pubmed: 31557890
Nat Genet. 2012 Dec;44(12):1341-8
pubmed: 23143594
Am J Pathol. 2007 Jul;171(1):32-42
pubmed: 17591951
Am J Clin Dermatol. 2017 Aug;18(4):583-590
pubmed: 28342016
J Dermatol Sci. 1999 Nov;21(3):135-46
pubmed: 10527374
BMC Genomics. 2016 Oct 28;17(1):841
pubmed: 27793094
Can Med Assoc J. 1962 Dec 15;87(24):1271-4
pubmed: 20327334
Acta Derm Venereol. 2019 Feb 1;99(2):196-205
pubmed: 30320872
Reumatologia. 2019;57(4):234-238
pubmed: 31548750
J Leukoc Biol. 2020 Aug;108(2):485-491
pubmed: 32170886
Expert Opin Drug Saf. 2016 Oct;15(10):1413-20
pubmed: 27545070
J Allergy Clin Immunol. 2003 Dec;112(6):1195-202
pubmed: 14657882
Regen Med. 2016 Sep;11(6):545-57
pubmed: 27513102
J Immunol. 2010 Mar 24;184(9):5263-5270
pubmed: 20335534
J Mol Med (Berl). 2005 Dec;83(12):964-75
pubmed: 16283139
J Dermatol. 2015 May;42(5):500-3
pubmed: 25728622
J Invest Dermatol. 2008 Jan;128(1):110-24
pubmed: 17637826
J Lipid Res. 2007 Dec;48(12):2531-46
pubmed: 17872588
Cell Rep. 2018 Oct 23;25(4):871-883
pubmed: 30355494
J Invest Dermatol. 2006 Apr;126(4):932-5
pubmed: 16456530
Eur J Dermatol. 2019 Aug 1;29(4):375-382
pubmed: 31625919
Nature. 2012 Dec 20;492(7429):S56-7
pubmed: 23254973
J Invest Dermatol. 2012 Jan;132(1):246-9
pubmed: 21850022
Mol Genet Genomics. 2018 Aug;293(4):957-966
pubmed: 29589160
Cell Physiol Biochem. 2018;50(1):15-27
pubmed: 30278433
Biochim Biophys Acta. 2014 Mar;1841(3):362-8
pubmed: 24120574
J Invest Dermatol. 2010 Jul;130(7):1829-40
pubmed: 20220767
Front Genet. 2018 Mar 16;9:83
pubmed: 29616078
PLoS One. 2011 Feb 22;6(2):e17160
pubmed: 21364948
J Immunol. 1996 Oct 15;157(8):3627-34
pubmed: 8871663
Int J Mol Sci. 2018 Sep 26;19(10):
pubmed: 30261611
Prostaglandins Leukot Essent Fatty Acids. 1995 Jan;52(1):1-15
pubmed: 7708814
Prog Lipid Res. 2006 May;45(3):237-49
pubmed: 16564093
Front Genet. 2019 Jan 22;9:636
pubmed: 30723492
J Am Acad Dermatol. 1985 Sep;13(3):450-6
pubmed: 4056119
Arch Dermatol. 1963 Jul;88:38-47
pubmed: 14042660
Nat Genet. 2010 Nov;42(11):985-90
pubmed: 20953190
J Invest Dermatol. 1990 Nov;95(5 Suppl):2S-4S
pubmed: 16788615
J Invest Dermatol. 2018 Sep;138(9):2010-2023
pubmed: 29689250
Am J Hum Genet. 2007 Feb;80(2):273-90
pubmed: 17236132
J Dermatol Sci. 2009 Jan;53(1):19-25
pubmed: 18783923
Am J Clin Dermatol. 2003;4(12):833-42
pubmed: 14640776
Nature. 2007 Feb 22;445(7130):866-73
pubmed: 17314973
Hum Mol Genet. 2001 Aug 15;10(17):1793-805
pubmed: 11532989
J Clin Invest. 1999 Dec;104(11):1527-37
pubmed: 10587516
Immunopharmacology. 2000 May;47(2-3):119-25
pubmed: 10878286
J Invest Dermatol. 2018 Mar;138(3):542-548
pubmed: 29031612
J Invest Dermatol. 2002 Feb;118(2):362-5
pubmed: 11841557
Dis Model Mech. 2012 Jul;5(4):423-33
pubmed: 22730473
Bioessays. 2017 Jul;39(7):
pubmed: 28590035
PLoS One. 2013 May 15;8(5):e63619
pubmed: 23691076
J Invest Dermatol. 2005 Jan;124(1):282-4
pubmed: 15654990
Nature. 2005 Sep 15;437(7057):369-75
pubmed: 16163348
Clin Rev Allergy Immunol. 2007 Oct;33(1-2):45-56
pubmed: 18094946
J Invest Dermatol. 2014 Jul;134(7):1828-1838
pubmed: 24441097
Front Genet. 2019 Apr 05;10:317
pubmed: 31024627
Mediators Inflamm. 2010;2010:
pubmed: 20706605
J Invest Dermatol. 2019 Jul;139(7):1470-1479
pubmed: 30641039
Nat Med. 2009 Dec;15(12):1377-82
pubmed: 19966777
Mol Med Rep. 2019 Mar;19(3):1529-1542
pubmed: 30592269
Br J Dermatol. 2013 Aug;169(2):412-6
pubmed: 23574549
PLoS One. 2008 Jul 16;3(7):e2737
pubmed: 18648529
J Dermatol. 2018 Mar;45(3):264-272
pubmed: 29226422
Curr Dermatol Rep. 2014 Mar;3(1):61-78
pubmed: 25580373
J Invest Dermatol. 2016 Sep;136(9):1820-1830
pubmed: 27206706
Am J Hum Genet. 2012 May 4;90(5):784-95
pubmed: 22521418
Biomed Res Int. 2017;2017:8717369
pubmed: 29204449
Annu Rev Immunol. 2014;32:227-55
pubmed: 24655295
J Exp Med. 2006 Oct 2;203(10):2271-9
pubmed: 16982811
J Invest Dermatol. 1999 Aug;113(2):214-20
pubmed: 10469306
Nat Commun. 2015 May 05;6:7001
pubmed: 25939698
Prog Lipid Res. 2014 Jan;53:124-44
pubmed: 24362249
Dermatology. 2005;211(2):103-6
pubmed: 16088154
Nature. 2002 Jun 20;417(6891):861-6
pubmed: 12075355
Cell Rep. 2018 Oct 23;25(4):823-824
pubmed: 30355488
Sci Rep. 2018 Jun 5;8(1):8590
pubmed: 29872130
Exp Dermatol. 2018 May;27(5):512-519
pubmed: 29502346
Bioinformatics. 2015 Dec 15;31(24):3938-45
pubmed: 26338770
Biochem Soc Trans. 2002 Nov;30(Pt 6):1076-9
pubmed: 12440976
J Invest Dermatol. 2012 Nov;132(11):2552-64
pubmed: 22763790
Sci Rep. 2018 Jul 27;8(1):11368
pubmed: 30054515
Immunity. 2018 Jul 17;49(1):66-79.e5
pubmed: 29980436
J Invest Dermatol. 2008 Mar;128(3):606-15
pubmed: 17928892
Nat Rev Genet. 2019 Dec;20(12):747-759
pubmed: 31605095
Immunity. 2013 Nov 14;39(5):899-911
pubmed: 24211183
Pharmacogenomics J. 2001;1(4):272-87
pubmed: 11911124
J Invest Dermatol. 2009 Dec;129(12):2795-804
pubmed: 19571819
J Am Acad Dermatol. 1993 Sep;29(3):428-34
pubmed: 8349859
J Invest Dermatol. 2019 May;139(5):995-996
pubmed: 31010530
BioDrugs. 2006;20(2):93-103
pubmed: 16626167
Genes Immun. 2007 Jan;8(1):1-12
pubmed: 17093502
An Bras Dermatol. 2016 Apr;91(2):160-6
pubmed: 27192514
J Invest Dermatol. 2007 Jan;127(1):163-9
pubmed: 16858420
Int J Mol Sci. 2017 Jul 29;18(8):
pubmed: 28758927
J Am Acad Dermatol. 2014 Mar;70(3):512-6
pubmed: 24388724
Lancet. 2003 Apr 5;361(9364):1197-204
pubmed: 12686053
J Invest Dermatol. 2004 Nov;123(5):892-901
pubmed: 15482477
Sci Rep. 2017 Dec 22;7(1):18045
pubmed: 29273799
Adv Healthc Mater. 2018 Jun;7(12):e1701405
pubmed: 29542274
Int J Dermatol. 2018 Dec;57(12):1481-1484
pubmed: 30105747
Signal Transduct Target Ther. 2017;2:
pubmed: 29158945
Hum Mol Genet. 2011 Oct 15;20(20):4025-40
pubmed: 21807764
J Autoimmun. 2010 May;34(3):J314-21
pubmed: 20034760
Int Immunol. 2016 Sep;28(9):443-52
pubmed: 26944069
Immunity. 2012 Jul 27;37(1):74-84
pubmed: 22727489
Nat Biotechnol. 2006 Sep;24(9):1151-61
pubmed: 16964229
Prostaglandins Leukot Essent Fatty Acids. 2013 Jan;88(1):131-8
pubmed: 22521864
Physiol Genomics. 2003 Mar 18;13(1):69-78
pubmed: 12644634
J Immunol. 1997 Dec 1;159(11):5661-70
pubmed: 9548510
Clin Dermatol. 2014 May-Jun;32(3):343-50
pubmed: 24767182