A Compartment-Based Mathematical Model for Studying Convective Aerosol Transport in Newborns Receiving Nebulized Drugs during Noninvasive Respiratory Support.
aerosol neonates
convective transport
lung deposition
mathematical model
noninvasive ventilation
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
30 Sep 2020
30 Sep 2020
Historique:
received:
29
07
2020
revised:
24
09
2020
accepted:
28
09
2020
entrez:
3
10
2020
pubmed:
4
10
2020
medline:
4
10
2020
Statut:
epublish
Résumé
Nebulization could be a valuable solution to administer drugs to neonates receiving noninvasive respiratory support. Small and irregular tidal volumes and air leaks at the patient interface, which are specific characteristics of this patient population and are primarily responsible for the low doses delivered to the lung (D
Identifiants
pubmed: 33007894
pii: pharmaceutics12100936
doi: 10.3390/pharmaceutics12100936
pmc: PMC7600494
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Respir Care. 2014 Feb;59(2):263-73
pubmed: 23821760
J Aerosol Med Pulm Drug Deliv. 2020 Feb;33(1):21-33
pubmed: 31436493
Respir Care. 2014 Mar;59(3):443-4
pubmed: 24587482
Am J Perinatol. 2019 Jul;36(S 02):S13-S17
pubmed: 31238352
Pediatr Res. 2010 Jan;67(1):11-6
pubmed: 19755932
Pediatr Res. 2009 Mar;65(3):352-6
pubmed: 19391251
Arch Dis Child Fetal Neonatal Ed. 2018 Jan;103(1):F29-F35
pubmed: 28970314
Pediatr Res. 2008 Aug;64(2):141-6
pubmed: 18391845
Arch Dis Child Fetal Neonatal Ed. 2019 May;104(3):F313-F319
pubmed: 30049729
Arch Dis Child Fetal Neonatal Ed. 2008 Jul;93(4):F275-9
pubmed: 18192330
Respir Res. 2019 Jul 2;20(1):134
pubmed: 31266508
Neonatology. 2019;115(4):432-450
pubmed: 30974433
Pharmaceutics. 2020 Mar 12;12(3):
pubmed: 32178276
Pediatr Pulmonol. 1997 Sep;24(3):222-4
pubmed: 9330420
Lancet. 1992 Feb 1;339(8788):283-7
pubmed: 1346292
Pediatr Dermatol. 2012 Jan-Feb;29(1):45-8
pubmed: 21995718
Respir Care. 2015 Jul;60(7):1000-6
pubmed: 25715346
Am J Orthod. 1969 Jun;55(6):566-77
pubmed: 5253955
J Aerosol Med Pulm Drug Deliv. 2014 Feb;27(1):58-65
pubmed: 23509937
Pediatr Pulmonol. 2018 Jun;53(6):755-761
pubmed: 29687665
Respir Care. 2009 Nov;54(11):1488-92
pubmed: 19863833
Arch Dis Child Fetal Neonatal Ed. 2005 Jan;90(1):F79-81
pubmed: 15613585
Crit Care Med. 2020 Jun;48(6):e523-e531
pubmed: 32301841
Pediatr Pulmonol. 2015 Nov;50(11):1099-106
pubmed: 25491434
Pediatr Pulmonol. 2020 Feb;55(2):514-520
pubmed: 31833668
Pharmaceutics. 2020 Apr 02;12(4):
pubmed: 32252349
Early Hum Dev. 2019 Jul;134:19-25
pubmed: 31121339
Acta Paediatr. 2000 Apr;89(4):460-4
pubmed: 10830460
Sci Rep. 2019 Apr 5;9(1):5720
pubmed: 30952897
PLoS One. 2018 Jul 12;13(7):e0200542
pubmed: 30001410
Pediatr Pulmonol. 2017 Mar;52(3):337-344
pubmed: 27392199
J Aerosol Med Pulm Drug Deliv. 2010 Oct;23(5):303-9
pubmed: 20455772