Personalized Medicine for the Infertile Male.

Biomarkers / blood Combined Modality Therapy Forecasting Genomics Humans Infertility, Male / diagnosis Male Precision Medicine / methods Proteomics Risk Assessment Treatment Outcome
Genomics Male infertility Personalized medicine Proteomics

Journal

The Urologic clinics of North America
ISSN: 1558-318X
Titre abrégé: Urol Clin North Am
Pays: United States
ID NLM: 0423221

Informations de publication

Date de publication:
Nov 2020
Historique:
entrez: 3 10 2020
pubmed: 4 10 2020
medline: 21 10 2020
Statut: ppublish

Résumé

Personalized medicine uses a patient's genotype, environment, and lifestyle choices to create a tailored diagnosis and therapy plan, with the goal of minimizing side effects, avoiding lost time with ineffective treatments, and guiding preventative strategies. Although most precision medicine strategies are still within the laboratory phase of development, this article reviews the promising technologies with the greatest potential to improve the diagnosis and treatment options for male infertility, including sperm cell transplantation, genomic editing, and new biomarker assays, based on the latest proteomic and epigenomic studies.

Identifiants

DOI: 10.1016/j.ucl.2020.07.003 PMID: 33008501
pubmed: 33008501
pii: S0094-0143(20)30043-4
doi: 10.1016/j.ucl.2020.07.003
pii:
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

523-536

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Danielle Velez (D)

Division of Urology, Department of Surgery, Brown University, 2 Dudley Street Suite 185, Providence, RI, USA.

Kathleen Hwang (K)

Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: hwangky@upmc.edu.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Personalized Medicine for the Infertile Male.
questionsmedicales.fr › Thérapeutique › Association thérapeutique › Personalized Medicine for the Infertile Male.
questionsmedicales.fr › Sciences sociales › Prévision › Personalized Medicine for the Infertile Male.
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génomique › Personalized Medicine for the Infertile Male.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Personalized Medicine for the Infertile Male.
questionsmedicales.fr › Maladies urogénitales › Maladies urogénitales de l'homme › Maladies de l'appareil génital mâle › Infertilité masculine › Personalized Medicine for the Infertile Male.
questionsmedicales.fr › Professions de santé › Médecine › Médecine clinique › Médecine de précision › Personalized Medicine for the Infertile Male.
questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Biochimie › Protéomique › Personalized Medicine for the Infertile Male.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Appréciation des risques › Personalized Medicine for the Infertile Male.
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Qualité des soins de santé › Mécanismes d'évaluation des soins de santé › Évaluation des résultats et des processus en soins de santé › Évaluation de résultat (soins) › Résultat thérapeutique › Personalized Medicine for the Infertile Male.