Comparison of vitreoretinal disorders in fellow eyes of lamellar macular holes versus epiretinal membrane foveoschisis.
Epiretinal membrane foveoschisis
Epiretinal proliferation
Lamellar macular hole
Müller glial cells
Spectral-domain optical coherence tomography
Journal
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
ISSN: 1435-702X
Titre abrégé: Graefes Arch Clin Exp Ophthalmol
Pays: Germany
ID NLM: 8205248
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
21
04
2020
accepted:
18
09
2020
revised:
21
08
2020
pubmed:
4
10
2020
medline:
19
8
2021
entrez:
3
10
2020
Statut:
ppublish
Résumé
To evaluate and compare the rate and characteristics of vitreoretinal disorders in fellow eyes of lamellar macular holes (LMH) versus epiretinal membrane foveoschisis (ERMF). Included patients in this retrospective study were divided into two groups based on spectral-domain optical coherence tomography (SD-OCT) features of their primary eye: LMH (group A) and ERMF (group B). Ninety-four patients were enrolled: 59 (62.8%) in group A and 35 (37.2%) in group B. Fellow eyes in group A had a higher rate of retinal detachment (8/59 [13.6%] vs. 0/35 [0%], P = 0.024), and full-thickness macular hole (FTMH) (11/59 [18.6%] vs. 2/35 [5.7%], P = 0.079), compared with fellow eyes in group B. In group A, 4/59 patients (6.8%) showed a bilateral LMH while none from group B had a LMH in their fellow eye (0/35 [0%]), P = 0.293. Additionally, epiretinal proliferation was noted in 30/59 (50.8%) fellow eyes in group A versus 3/35 (8.6%) fellow eyes in group B, P < 0.001. Longitudinal data were available for 80/94 patients. Over a mean follow-up of 37.4 ± 29.9 months, 1/48 (2.1%) fellow eyes from group A developed a FTMH and 2/48 (4.2%) developed a LMH, while no FTMH or LMH occurred in fellow eyes of group B. Fellow eyes of LMH showed a high rate of macular and peripheral vitreoretinal disorders. In addition, epiretinal proliferation was detected in a higher number of fellow eyes of LMH versus ERMF. These findings suggest a bilateral process in eyes of patients with LMH.
Identifiants
pubmed: 33009974
doi: 10.1007/s00417-020-04950-y
pii: 10.1007/s00417-020-04950-y
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2611-2619Références
Haouchine B, Massin P, Tadayoni R et al (2004) Diagnosis of macular pseudoholes and lamellar macular holes by optical coherence tomography. Am J Ophthalmol 138:732–739
doi: 10.1016/j.ajo.2004.06.088
Gaudric A, Aloulou Y, Tadayoni R et al (2013) Macular pseudoholes with lamellar cleavage of their edge remain pseudoholes. Am J Ophthalmol 155:733–742
doi: 10.1016/j.ajo.2012.10.021
Govetto A, Dacquay Y, Farajzadeh M et al (2016) Lamellar macular hole: two distinct clinical entities? Am J Ophthalmol 164:99–109
doi: 10.1016/j.ajo.2016.02.008
Gass JD (1975) Lamellar macular hole: a complication of cystoid macular edema after cataract extraction: a clinicopathologic case report. Trans Am Ophthalmol Soc 73:231–250
pubmed: 1246806
Duker JS, Kaiser PK, Binder S et al (2013) The international vitreomacular traction study group classification of vitreomacular adhesion, traction, and macular hole. Ophthalmology 120:2611–2619
doi: 10.1016/j.ophtha.2013.07.042
Hubschman JP, Govetto A, Spaide RF et al (2020) Optical coherence tomography-based consensus definition for lamellar macular hole. Br J Ophthalmol https://doi.org/10.1136/bjophthalmol-2019-315432
Pang CE, Spaide RF, Freund KB (2014) Epiretinal proliferation seen in association with lamellar macular holes: a distinct clinical entity. Retina 34:1513–1523
doi: 10.1097/IAE.0000000000000163
Compera D, Entchev E, Haritoglou C et al (2015) Correlative microscopy of lamellar hole-associated epiretinal proliferation. J Ophthalmol 2015:1–8
doi: 10.1155/2015/450212
Pang CE, Maberley DA, Freund KB et al (2016) Lamellar hole-associated epiretinal proliferation: a clinicopathologic correlation. Retina 36:1408–1412
doi: 10.1097/IAE.0000000000001069
Itoh Y, Levison AL, Kaiser PK et al (2016) Prevalence and characteristics of hyporeflective preretinal tissue in vitreomacular interface disorders. Br J Ophthalmol 100:399–404
doi: 10.1136/bjophthalmol-2015-306986
Lai T-T, Yang C-M (2018) Lamellar hole-associated epiretinal proliferation in lamellar macular hole and full-thickness macular hole in high myopia. Retina 38:1316–1323
doi: 10.1097/IAE.0000000000001708
Takahashi H, Inoue M, Itoh Y et al (2018) Macular dehiscence-associated epiretinal proliferation in eyes with full-thickness macular hole. Retina 00:1–9
doi: 10.1097/IAE.0000000000002366
Nava U, Cereda MG, Bottoni F et al (2017) Long-term follow-up of fellow eye in patients with lamellar macular hole. Graefes Arch Clin Exp Ophthalmol 255:1485–1492
doi: 10.1007/s00417-017-3652-7
Ezra E, Wells JA, Gray RH et al (1998) Incidence of idiopathic full-thickness macular holes in fellow eyes. A 5-year prospective natural history study. Ophthalmology 105:353–359
doi: 10.1016/S0161-6420(98)93562-X
Dell’Omo R, Vogt D, Schumann RG et al (2018) The relationship between blue-fundus autofluorescence and optical coherence tomography in eyes with lamellar macular holes. Invest Ophthalmol Vis Sci 59:3079–3087
doi: 10.1167/iovs.18-24379
Schumann RG, Eibl KH, Zhao F et al (2011) Immunocytochemical and ultrastructural evidence of glial cells and hyalocytes in internal limiting membrane specimens of idiopathic macular holes. Invest Ophthalmol Vis Sci 52:7822–7834
doi: 10.1167/iovs.11-7514
Pang CE, Spaide RF, Freund KB (2015) Comparing functional and morphologic characteristics of lamellar macular holes with and without lamellar hole-associated epiretinal proliferation. Retina 35:720–726
doi: 10.1097/IAE.0000000000000390
Dell’Omo R, De Turris S, Filipelli M et al (2019) Foveal abnormality associated with epiretinal tissue of medium reflectivity and increased blue-light fundus autofluorescence signal (FATIAS). Graefes Arch Clin Exp Ophthalmo 257:2601–2612. https://doi.org/10.1007/s00417-019-04451-7
doi: 10.1007/s00417-019-04451-7
Bringmann A, Wiedemann P (2009) Involvement of Müller glial cells in epiretinal membrane formation. Graefes Arch Clin Exp Ophthalmol 247:865–883
doi: 10.1007/s00417-009-1082-x
MacDonald RB, Randlett O, Oswald J et al (2015) Müller glia provide essential tensile strength to the developing retina. J Cell Biol 210:1075–1083
doi: 10.1083/jcb.201503115
Govetto A, Bhavsar KV, Virgili G et al (2017) Tractional abnormalities of the central foveal bouquet in epiretinal membranes: clinical spectrum and pathophysiological perspectives. Am J Ophthalmol 184:167–180
doi: 10.1016/j.ajo.2017.10.011
Lu Y-B, Pannicke T, Wei E-Q et al (2013) Biomechanical properties of retinal glial cells: comparative and developmental data. Exp Eye Res 113:60–65
doi: 10.1016/j.exer.2013.05.012
Fabian ID, Moisseiev E, Moisseiev J et al (2012) Macular hole after vitrectomy for primary rhegmatogenous retinal detachment. Retina 32:511–519
doi: 10.1097/IAE.0b013e31821f5d81
Compera D, Schumann RG, Cereda MG et al (2018) Progression of lamellar hole-associated epiretinal proliferation and retinal changes during long-term follow-up. Br J Ophthalmol 102:84–90
doi: 10.1136/bjophthalmol-2016-310128
Smiddy WE (2008) Macular hole formation without vitreofoveal traction. Arch Ophthalmol 126:737–738
doi: 10.1001/archopht.126.5.737
Luna G, Keeley PW, Reese BE et al (2016) Astrocyte structural reactivity and plasticity in models of retinal detachment. Exp Eye Res 150:4–21
doi: 10.1016/j.exer.2016.03.027
Pfeiffer RL, Marc RE, Kondo M et al (2016) Müller cell metabolic chaos during retinal degeneration. Exp Eye Res 150:62–70
doi: 10.1016/j.exer.2016.04.022