Drug discovery and development in idiopathic pulmonary fibrosis: challenges and opportunities.

Animals Drug Combinations Drug Development Drug Discovery Drug Therapy, Combination Humans Idiopathic Pulmonary Fibrosis / drug therapy

Journal

Drug discovery today
ISSN: 1878-5832
Titre abrégé: Drug Discov Today
Pays: England
ID NLM: 9604391

Informations de publication

Date de publication:
12 2020
Historique:
received: 04 02 2020
revised: 25 08 2020
accepted: 17 09 2020
pubmed: 4 10 2020
medline: 7 10 2021
entrez: 3 10 2020
Statut: ppublish

Résumé

The pharmacological and adverse effect profiles of the two approved therapies for IPF make the development of new therapies challenging. Considering the similarity of the characteristics of drug candidates to Standard of Care is important in defining positioning and development strategies for this disease.

Identifiants

DOI: 10.1016/j.drudis.2020.09.019 PMID: 33010480
pubmed: 33010480
pii: S1359-6446(20)30376-7
doi: 10.1016/j.drudis.2020.09.019
pii:
doi:

Substances chimiques

Drug Combinations 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2277-2283

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Simon Cruwys (S)

TherapeutAix UG, Juttastrasse 18, 52066, Aachen, Germany.

Peter Hein (P)

TherapeutAix UG, Juttastrasse 18, 52066, Aachen, Germany.

Bob Humphries (B)

TherapeutAix UG, Juttastrasse 18, 52066, Aachen, Germany.

Darcey Black (D)

TherapeutAix UG, Juttastrasse 18, 52066, Aachen, Germany. Electronic address: darcey@therapeutaix.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Drug discovery and development in idiopathic...
questionsmedicales.fr › Préparations pharmaceutiques › Association médicamenteuse › Drug discovery and development in idiopathic...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Drug discovery and development in idiopathic...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Drug discovery and development in idiopathic...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Association de médicaments › Drug discovery and development in idiopathic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Drug discovery and development in idiopathic...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Maladies pulmonaires › Pneumopathies interstitielles › Fibrose pulmonaire idiopathique › Drug discovery and development in idiopathic...