Adenylate Cyclase Toxin Tinkering With Monocyte-Macrophage Differentiation.
Adenylate Cyclase Toxin
/ pharmacology
Animals
Antigen Presentation
/ drug effects
Bordetella pertussis
/ physiology
Cell Dedifferentiation
/ drug effects
Cell Differentiation
Cyclic AMP
/ physiology
Host-Pathogen Interactions
/ immunology
Humans
Immunity, Innate
/ drug effects
Immunity, Mucosal
/ drug effects
Macrophages, Alveolar
/ cytology
Mice
Models, Biological
Monocytes
/ cytology
Phagocytosis
Respiratory System
/ drug effects
Second Messenger Systems
/ drug effects
Bordetella pertussis
adenylate cyclase toxin
dedifferentiation
macrophages
monocytes
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2020
2020
Historique:
received:
25
06
2020
accepted:
10
08
2020
entrez:
5
10
2020
pubmed:
6
10
2020
medline:
1
5
2021
Statut:
epublish
Résumé
Circulating inflammatory monocytes are attracted to infected mucosa and differentiate into macrophage or dendritic cells endowed with enhanced bactericidal and antigen presenting capacities. In this brief Perspective we discuss the newly emerging insight into how the cAMP signaling capacity of
Identifiants
pubmed: 33013916
doi: 10.3389/fimmu.2020.02181
pmc: PMC7516048
doi:
Substances chimiques
Adenylate Cyclase Toxin
0
Cyclic AMP
E0399OZS9N
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2181Informations de copyright
Copyright © 2020 Ahmad and Sebo.
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