Variation rs2235503 C > A Within the Promoter of
diagnostic biomarkers
eQTL
fluorescent reporter assay
malignant pleural mesothelioma
single nucleotide polymorphisms
soluble mesothelin-related peptide
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2020
2020
Historique:
received:
05
05
2020
accepted:
31
07
2020
entrez:
5
10
2020
pubmed:
6
10
2020
medline:
6
10
2020
Statut:
epublish
Résumé
Soluble mesothelin-related peptide (SMRP) is a promising biomarker for malignant pleural mesothelioma (MPM), but several confounding factors can reduce SMRP-based test's accuracy. The identification of these confounders could improve the diagnostic performance of SMRP. In this study, we evaluated the sequence of 1,000 base pairs encompassing the minimal promoter region of the
Identifiants
pubmed: 33014022
doi: 10.3389/fgene.2020.00975
pmc: PMC7461867
doi:
Types de publication
Journal Article
Langues
eng
Pagination
975Informations de copyright
Copyright © 2020 Silvestri, Pucci, De Santi, Dell’Anno, Miglietta, Corrado, Nicolí, Marolda, Cipollini, Pellegrino, Evangelista, Bonotti, Foddis, Cristaudo, Landi and Gemignani.
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