Endothelial Ribonuclease 1 in Cardiovascular and Systemic Inflammation.
endothelial cells
extracellular RNA
inflammation
ribonuclease 1
vascular diseases
Journal
Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250
Informations de publication
Date de publication:
2020
2020
Historique:
received:
26
06
2020
accepted:
14
08
2020
entrez:
5
10
2020
pubmed:
6
10
2020
medline:
6
10
2020
Statut:
epublish
Résumé
The vascular endothelial cell layer forms the inner lining of all blood vessels to maintain proper functioning of the vascular system. However, dysfunction of the endothelium depicts a major issue in context of vascular pathologies, such as atherosclerosis or thrombosis that cause several million deaths per year worldwide. In recent years, the endothelial extracellular endonuclease Ribonuclease 1 (RNase1) was described as a key player in regulation of vascular homeostasis by protecting endothelial cells from detrimental effects of the damage-associated molecular pattern extracellular RNA upon acute inflammation. Despite this protective function, massive dysregulation of RNase1 was observed during prolonged endothelial cell inflammation resulting in progression of several vascular diseases. For the first time, this review article outlines the current knowledge on endothelial RNase1 and its role in function and dysfunction of the endothelium, thereby focusing on the intensive research from recent years: Uncovering the underlying mechanisms of RNase1 function and regulation in response to acute as well as long-term inflammation, the role of RNase1 in context of vascular, inflammatory and infectious diseases and the potential to develop novel therapeutic options to treat these pathologies against the background of RNase1 function in endothelial cells.
Identifiants
pubmed: 33015070
doi: 10.3389/fcell.2020.576491
pmc: PMC7500176
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
576491Informations de copyright
Copyright © 2020 Bedenbender and Schmeck.
Références
Hamostaseologie. 2019 Jun;39(2):128-139
pubmed: 30620989
Vaccines (Basel). 2018 Nov 20;6(4):
pubmed: 30463297
Nat Rev Immunol. 2007 Oct;7(10):803-15
pubmed: 17893694
Protein Eng. 1998 Dec;11(12):1285-92
pubmed: 9930679
Thromb Haemost. 2014 Dec;112(6):1110-9
pubmed: 25354936
Front Immunol. 2018 May 16;9:1012
pubmed: 29867984
Eur J Biochem. 2000 Jan;267(2):566-72
pubmed: 10632727
Cell. 2007 Feb 23;128(4):693-705
pubmed: 17320507
APMIS. 2002 Jun;110(6):458-68
pubmed: 12193207
Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):2920-4
pubmed: 8159680
Chonnam Med J. 2016 Jan;52(1):1-11
pubmed: 26865995
Med Res Rev. 2001 Mar;21(2):129-45
pubmed: 11223862
Eur J Cardiothorac Surg. 2015 Nov;48(5):732-7; discussion 737
pubmed: 25564211
J Biomed Biotechnol. 2011;2011:690848
pubmed: 21197454
FASEB J. 2019 Aug;33(8):9017-9029
pubmed: 31039328
J Clin Invest. 1995 Jul;96(1):60-8
pubmed: 7542286
FASEB J. 2008 Oct;22(10):3549-60
pubmed: 18606865
Biomed Pharmacother. 2017 Jun;90:62-68
pubmed: 28343072
Biol Chem Hoppe Seyler. 1994 May;375(5):357-63
pubmed: 8074810
Nat Genet. 2008 Jul;40(7):897-903
pubmed: 18552846
Nat Rev Immunol. 2008 Nov;8(11):874-87
pubmed: 18846099
Sci Signal. 2010 Jan 19;3(105):cm1
pubmed: 20086235
J Immunol. 2004 Nov 15;173(10):6134-42
pubmed: 15528350
Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6388-93
pubmed: 17405864
Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):806-12
pubmed: 17255531
J Clin Invest. 2012 Aug;122(8):2711-9
pubmed: 22850880
J Cell Biochem. 2002;86(3):540-52
pubmed: 12210760
Nat Rev Immunol. 2015 Jun;15(6):362-74
pubmed: 26008591
Arterioscler Thromb Vasc Biol. 2011 Apr;31(4):851-60
pubmed: 21233448
Curr Med Chem. 2005;12(25):2979-94
pubmed: 16378500
Crit Rev Biomed Eng. 2001;29(2):247-78
pubmed: 11417757
J Biochem. 1986 Jan;99(1):17-25
pubmed: 3514589
Handb Exp Pharmacol. 2006;(176 Pt 1):107-44
pubmed: 16999218
Curr Pharm Biotechnol. 2018;19(15):1182-1188
pubmed: 30605055
J Thromb Haemost. 2019 Jan;17(1):6-18
pubmed: 30375718
J Biol Chem. 2007 Feb 16;282(7):4626-33
pubmed: 17150966
Oncologist. 2007 Oct;12(10):1247-52
pubmed: 17962618
Circ Res. 2016 Feb 5;118(3):469-79
pubmed: 26846641
JCI Insight. 2020 Apr 23;5(8):
pubmed: 32213712
Int J Mol Sci. 2016 Aug 05;17(8):
pubmed: 27527162
Leukemia. 2018 Jan;32(1):1-10
pubmed: 28951560
FEBS Lett. 2010 Jun 3;584(11):2194-200
pubmed: 20388512
Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6062-7
pubmed: 15075390
Blood. 2007 Oct 1;110(7):2457-65
pubmed: 17576819
J Biol Chem. 2002 Aug 30;277(35):31826-33
pubmed: 12082111
Handb Exp Pharmacol. 2006;(176 Pt 2):97-133
pubmed: 16999226
IUBMB Life. 2006 Sep;58(9):508-14
pubmed: 17002978
J Biol Chem. 2007 Nov 9;282(45):33227-36
pubmed: 17827154
FASEB J. 2014 Feb;28(2):752-60
pubmed: 24174426
EMBO J. 2002 Sep 2;21(17):4593-9
pubmed: 12198161
Biol Cell. 2009 Apr;101(4):193-205
pubmed: 19207105
Circulation. 2014 Feb 4;129(5):598-606
pubmed: 24201302
Cell. 1997 May 2;89(3):357-64
pubmed: 9150135
Pathophysiol Haemost Thromb. 2002 Sep-Dec;32(5-6):274-7
pubmed: 13679656
Biochemistry. 2011 Oct 4;50(39):8374-82
pubmed: 21827164
J Mol Biol. 2007 Apr 27;368(2):434-49
pubmed: 17350650
J Am Heart Assoc. 2014 Jan 03;3(1):e000683
pubmed: 24390148
Nat Rev Mol Cell Biol. 2008 Mar;9(3):206-18
pubmed: 18292778
J Am Heart Assoc. 2017 Jun 21;6(6):
pubmed: 28637776
Glycobiology. 2007 Apr;17(4):388-400
pubmed: 17229815
Cancer Sci. 2006 Dec;97(12):1315-20
pubmed: 17032310
Hamostaseologie. 2013;33(1):37-42
pubmed: 23328880
RNA. 2019 Aug;25(8):921-934
pubmed: 31053653
Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1454-8
pubmed: 11171972
AIDS Res Hum Retroviruses. 2006 Sep;22(9):897-907
pubmed: 16989616
AIDS. 2003 Mar 7;17(4):481-6
pubmed: 12598767
Biochemistry. 2003 Sep 2;42(34):10182-90
pubmed: 12939146
Prog Nucleic Acid Res Mol Biol. 2005;80:349-74
pubmed: 16164979
Biochem J. 2017 Jun 21;474(13):2219-2233
pubmed: 28495858
Biochemistry. 2019 Feb 19;58(7):987-996
pubmed: 30633504
Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2747-51
pubmed: 16143643
Nat Rev Nephrol. 2019 Jun;15(6):346-366
pubmed: 30858582
Sci Rep. 2016 Nov 28;6:37758
pubmed: 27892961
Arterioscler Thromb Vasc Biol. 2006 May;26(5):1002-7
pubmed: 16469951
Biochem J. 1988 Oct 15;255(2):501-5
pubmed: 3202829
Biochemistry. 1985 Sep 24;24(20):5480-6
pubmed: 4074709
J Cell Biochem. 2004 Sep 1;93(1):57-67
pubmed: 15352162
J Cell Physiol. 2003 Sep;196(3):430-43
pubmed: 12891700
FASEB J. 2009 Jul;23(7):2100-9
pubmed: 19246491
Ann N Y Acad Sci. 2001 Sep;945:172-8
pubmed: 11708475
J Biol Chem. 2004 Apr 9;279(15):15524-30
pubmed: 14749328
Nat Rev Immunol. 2004 Jul;4(7):499-511
pubmed: 15229469
Angiogenesis. 2013 Apr;16(2):387-404
pubmed: 23143660
J Virol. 1998 Apr;72(4):2752-9
pubmed: 9525594
Cancer Res. 2013 Aug 15;73(16):5080-9
pubmed: 23774209
Thromb Haemost. 2011 Feb;105(2):345-55
pubmed: 21103661
Nat Rev Dis Primers. 2019 Aug 16;5(1):56
pubmed: 31420554
Eur J Pharmacol. 2009 Dec 25;625(1-3):181-9
pubmed: 19825371
Blood. 2011 May 12;117(19):5033-43
pubmed: 21266719
Glycobiology. 2003 Apr;13(4):227-44
pubmed: 12626415
J Immunol. 2016 Oct 1;197(7):2589-97
pubmed: 27549172
Biochem J. 2003 Jan 1;369(Pt 1):1-15
pubmed: 12396231
Cell Death Differ. 2006 May;13(5):816-25
pubmed: 16410796
Int J Biol Sci. 2013 Nov 09;9(10):1057-69
pubmed: 24250251
Cell Tissue Res. 2014 Mar;355(3):635-45
pubmed: 24626811
DNA Cell Biol. 1997 Apr;16(4):413-9
pubmed: 9150428
J Leukoc Biol. 2007 Jan;81(1):1-5
pubmed: 17032697
Biochem Biophys Res Commun. 1989 May 30;161(1):121-6
pubmed: 2730651
Cancer Res. 1984 Apr;44(4):1682-7
pubmed: 6704974
Curr Neurovasc Res. 2009 Feb;6(1):12-9
pubmed: 19355922
Nat Rev Drug Discov. 2003 Sep;2(9):717-26
pubmed: 12951578
Autoimmun Rev. 2010 Oct;9(12):830-4
pubmed: 20678595
Nature. 1998 Oct 29;395(6705):917-21
pubmed: 9804427
Nat Immunol. 2003 Mar;4(3):269-73
pubmed: 12548285
FEBS J. 2011 Apr;278(6):862-76
pubmed: 21232017