Optical Coherence Tomography Angiography Analysis of Retinal and Choroidal Vascular Networks during Acute, Relapsing, and Quiescent Stages of Macular Toxoplasma Retinochoroiditis.
Adult
Capillaries
/ parasitology
Choroid
/ parasitology
Female
Fluorescein Angiography
/ methods
Humans
Male
Microvessels
/ parasitology
Prospective Studies
Retina
/ parasitology
Retinal Vessels
/ parasitology
Tomography, Optical Coherence
/ methods
Toxoplasma
/ pathogenicity
Toxoplasmosis, Ocular
/ parasitology
Visual Acuity
/ physiology
Journal
BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173
Informations de publication
Date de publication:
2020
2020
Historique:
received:
25
03
2020
revised:
04
07
2020
accepted:
02
09
2020
entrez:
5
10
2020
pubmed:
6
10
2020
medline:
30
4
2021
Statut:
epublish
Résumé
To highlight the advantages of optical coherence tomography angiography (OCTA) in delineating the morphological features of the retinal and choroidal vascular network during acute, relapsing, and quiescent stages of macular toxoplasma retinochoroiditis. This prospective study included patients presenting with both active and quiescent ocular toxoplasmoses. OCTA was obtained to diagnose and follow the subsequent vascular network changes at diagnosis and six months after acute presentation. Twenty-three eyes of 23 patients were included. In active lesions, OCTA showed extensive, well-delineated areas of intense hyposignal and perifoveal capillary arcade disruption in the parafoveal superficial capillary plexus (pSCP) and less extensive hyposignal in the parafoveal deep capillary plexus (pDCP). Signals of decreased deep capillary density and disorganization were also seen in the choroid. In nonactive lesions, OCTA demonstrated a homogenous and equally attenuated grayish hyposignal of the pSCP and pDCP and a partial restoration of the nonperfused choroidal areas. OCTA is a useful technique for vascular network analysis in toxoplasma retinochoroiditis. It allows the visualization of the different network changes and behaviors during the different stages of the infection.
Identifiants
pubmed: 33015168
doi: 10.1155/2020/4903735
pmc: PMC7512044
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4903735Informations de copyright
Copyright © 2020 Georges Azar et al.
Déclaration de conflit d'intérêts
The authors declare that there is no conflict of interest.
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