Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research.
Contaminants of emerging concern
Per- and polyfluoroalkyl substances
Perfluorooctane sulfonate
Perfluorooctanoic acid
Persistent compounds
Journal
Environmental toxicology and chemistry
ISSN: 1552-8618
Titre abrégé: Environ Toxicol Chem
Pays: United States
ID NLM: 8308958
Informations de publication
Date de publication:
03 2021
03 2021
Historique:
received:
20
07
2020
revised:
29
08
2020
accepted:
20
09
2020
pubmed:
6
10
2020
medline:
25
11
2021
entrez:
5
10
2020
Statut:
ppublish
Résumé
Reports of environmental and human health impacts of per- and polyfluoroalkyl substances (PFAS) have greatly increased in the peer-reviewed literature. The goals of the present review are to assess the state of the science regarding toxicological effects of PFAS and to develop strategies for advancing knowledge on the health effects of this large family of chemicals. Currently, much of the toxicity data available for PFAS are for a handful of chemicals, primarily legacy PFAS such as perfluorooctanoic acid and perfluorooctane sulfonate. Epidemiological studies have revealed associations between exposure to specific PFAS and a variety of health effects, including altered immune and thyroid function, liver disease, lipid and insulin dysregulation, kidney disease, adverse reproductive and developmental outcomes, and cancer. Concordance with experimental animal data exists for many of these effects. However, information on modes of action and adverse outcome pathways must be expanded, and profound differences in PFAS toxicokinetic properties must be considered in understanding differences in responses between the sexes and among species and life stages. With many health effects noted for a relatively few example compounds and hundreds of other PFAS in commerce lacking toxicity data, more contemporary and high-throughput approaches such as read-across, molecular dynamics, and protein modeling are proposed to accelerate the development of toxicity information on emerging and legacy PFAS, individually and as mixtures. In addition, an appropriate degree of precaution, given what is already known from the PFAS examples noted, may be needed to protect human health. Environ Toxicol Chem 2021;40:606-630. © 2020 SETAC.
Identifiants
pubmed: 33017053
doi: 10.1002/etc.4890
pmc: PMC7906952
mid: NIHMS1667049
doi:
Substances chimiques
Alkanesulfonic Acids
0
Fluorocarbons
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
606-630Subventions
Organisme : Intramural NIH HHS
ID : ZIA ES102785
Pays : United States
Informations de copyright
© 2020 SETAC.
Références
J Appl Toxicol. 2014 Jan;34(1):1-18
pubmed: 24166207
Toxicol Sci. 2011 Mar;120(1):42-58
pubmed: 21163906
Pediatr Res. 2016 Feb;79(2):348-57
pubmed: 26492286
Waste Manag. 2020 Apr 15;107:191-200
pubmed: 32304853
Environ Health Perspect. 2013 Apr;121(4):453-8
pubmed: 23360585
Epidemiology. 2012 Nov;23(6):799-805
pubmed: 22992575
Environ Sci Process Impacts. 2019 Nov 1;21(11):1835-1851
pubmed: 31576380
J Endocrinol Invest. 2017 Feb;40(2):105-121
pubmed: 27837466
Environ Res. 2016 Aug;149:239-246
pubmed: 27179585
Environ Res. 2015 Jan;136:8-14
pubmed: 25460614
Environ Int. 2019 May;126:445-453
pubmed: 30844580
Environ Health Perspect. 2012 May;120(5):655-60
pubmed: 22289616
Arch Pediatr Adolesc Med. 2010 Sep;164(9):860-9
pubmed: 20819969
Reprod Toxicol. 2016 Oct;65:230-235
pubmed: 27544573
J Occup Health. 2013;55(3):184-94
pubmed: 23574777
Environ Int. 2020 Mar;136:105358
pubmed: 32044175
EFSA J. 2020 Sep 17;18(9):e06223
pubmed: 32994824
Toxicol Sci. 2018 Oct 1;165(2):475-486
pubmed: 29939337
Toxicol Sci. 2010 Feb;113(2):305-14
pubmed: 19915082
J Immunotoxicol. 2013 Oct-Dec;10(4):373-9
pubmed: 23350954
Toxicol Sci. 2003 Aug;74(2):369-81
pubmed: 12773773
Curr Environ Health Rep. 2018 Mar;5(1):1-19
pubmed: 29556975
PLoS Biol. 2017 Dec 20;15(12):e2002855
pubmed: 29261653
Environ Health. 2020 Mar 14;19(1):33
pubmed: 32169067
Environ Health Perspect. 2013 May;121(5):625-30
pubmed: 23482063
Biochim Biophys Acta. 2015 Sep;1852(9):1765-78
pubmed: 26027904
Environ Int. 2017 Dec;109:128-135
pubmed: 28890218
Environ Res. 2014 Jul;132:251-63
pubmed: 24834819
Hum Reprod. 2015 Mar;30(3):701-9
pubmed: 25567616
Environ Health Perspect. 2019 Mar;127(3):37008
pubmed: 30920876
Arch Toxicol. 2016 May;90(5):1117-28
pubmed: 26041126
Environ Health Perspect. 2013 Nov-Dec;121(11-12):1313-8
pubmed: 24007715
Environ Int. 2016 Oct;95:86-92
pubmed: 27542758
Chemosphere. 2020 Feb;241:125074
pubmed: 31627108
Toxicol Appl Pharmacol. 2016 Jan 1;290:21-30
pubmed: 26548598
Epidemiology. 2012 Mar;23(2):257-63
pubmed: 22081060
Environ Sci Technol Lett. 2020 May 18;7(7):477-481
pubmed: 32944590
Anal Bioanal Chem. 2020 Apr;412(10):2251-2259
pubmed: 31760452
Chemosphere. 2019 Feb;217:100-110
pubmed: 30414542
Environ Health Perspect. 2017 Mar;125(3):416-421
pubmed: 27529882
J Phys Chem B. 2010 Nov 25;114(46):14860-74
pubmed: 21028884
Environ Health Perspect. 2009 Jun;117(6):923-7
pubmed: 19590684
Chemosphere. 2013 Nov;93(10):2419-25
pubmed: 24050716
Sci Total Environ. 2019 Feb 25;653:74-81
pubmed: 30408670
Int J Mol Sci. 2019 May 01;20(9):
pubmed: 31052427
Environ Res. 2019 Dec;179(Pt A):108743
pubmed: 31542491
Epidemiology. 2018 Nov;29(6):765-776
pubmed: 30063543
Environ Int. 2020 Apr;137:105581
pubmed: 32087483
Environ Health Perspect. 2008 Jun;116(6):716-22
pubmed: 18560525
J Expo Sci Environ Epidemiol. 2019 Mar;29(2):196-205
pubmed: 30185940
Environ Sci Technol. 2010 Sep 15;44(18):7123-9
pubmed: 20722423
Hum Reprod. 2009 May;24(5):1200-5
pubmed: 19176540
Environ Int. 2015 Apr;77:63-9
pubmed: 25647630
Semin Liver Dis. 2013 Nov;33(4):380-8
pubmed: 24222095
Curr Environ Health Rep. 2019 Sep;6(3):95-104
pubmed: 31090041
Children (Basel). 2017 Jun 06;4(6):
pubmed: 28587303
Environ Int. 2019 Dec;133(Pt A):105160
pubmed: 31518937
Environ Toxicol Chem. 2007 Nov;26(11):2440-7
pubmed: 17941737
Sci Total Environ. 2018 Sep 15;636:1058-1069
pubmed: 29913568
Arch Toxicol. 2018 Jan;92(1):83-119
pubmed: 29197930
Environ Health Perspect. 2008 May;116(5):573-7
pubmed: 18470285
Int J Environ Res Public Health. 2017 Jun 27;14(7):
pubmed: 28654008
PLoS One. 2020 Mar 16;15(3):e0230137
pubmed: 32176721
Int J Environ Res Public Health. 2020 Mar 04;17(5):
pubmed: 32143379
J Environ Sci (China). 2020 Feb;88:187-199
pubmed: 31862060
Environ Pollut. 2016 Nov;218:702-708
pubmed: 27496563
Toxicol Sci. 2016 Sep;153(1):186-97
pubmed: 27413108
Toxicol Sci. 2020 Jun 1;175(2):210-219
pubmed: 32219433
Epidemiology. 2013 Jul;24(4):569-76
pubmed: 23685825
Toxicology. 2014 Feb 28;316:43-54
pubmed: 24374136
Environ Health Perspect. 2018 Mar 01;126(3):037001
pubmed: 29498927
Environ Int. 2017 Jul;104:132-138
pubmed: 28392064
Environ Health Perspect. 2016 Jan;124(1):81-7
pubmed: 26058082
J Expo Sci Environ Epidemiol. 2019 Mar;29(2):148-156
pubmed: 30482935
Can Urol Assoc J. 2014 Jul;8(7-8):247-52
pubmed: 25210548
Environ Health. 2015 Jul 07;14:59
pubmed: 26148742
Environ Health. 2019 Jan 9;18(1):5
pubmed: 30626391
Environ Sci Pollut Res Int. 2019 Apr;26(12):12425-12434
pubmed: 30847808
Toxicol Lett. 2013 Nov 25;223(2):211-20
pubmed: 24035753
Environ Res. 2019 Feb;169:476-482
pubmed: 30530087
Am J Epidemiol. 2012 Nov 15;176(10):909-17
pubmed: 23079607
Environ Res. 2019 Dec;179(Pt A):108775
pubmed: 31593837
Toxicology. 2015 Jul 3;333:53-62
pubmed: 25868421
Environ Health Perspect. 2013 Oct;121(10):1207-13
pubmed: 23838280
Environ Sci Technol. 2013 Sep 17;47(18):10619-27
pubmed: 23980546
Environ Toxicol Chem. 2021 Mar;40(3):550-563
pubmed: 32845526
Eur J Public Health. 2018 Feb 1;28(1):180-185
pubmed: 28541558
Environ Int. 2020 Jan;134:105220
pubmed: 31744629
Environ Int. 2018 Apr;113:149-161
pubmed: 29425899
Environ Pollut. 2018 Nov;242(Pt A):894-904
pubmed: 30373035
Environ Health Perspect. 2019 Jan;127(1):14501
pubmed: 30632786
Toxicol Pathol. 2015 Jun;43(4):558-68
pubmed: 25398757
Ecotoxicol Environ Saf. 2019 May 30;173:461-468
pubmed: 30798190
Toxicol Rep. 2016 Aug 29;3:664-672
pubmed: 28959590
Int J Hyg Environ Health. 2018 Apr;221(3):569-577
pubmed: 29514764
JAMA. 2012 Jan 25;307(4):391-7
pubmed: 22274686
PLoS One. 2013 Apr 23;8(4):e61409
pubmed: 23626681
J Cheminform. 2017 Nov 28;9(1):61
pubmed: 29185060
Epidemiology. 2017 Jan;28(1):90-98
pubmed: 27541842
Toxicol Sci. 2011 Sep;123(1):290-303
pubmed: 21705711
Environ Sci Technol. 2017 Mar 7;51(5):2508-2518
pubmed: 28224793
Environ Health Perspect. 2007 Sep;115(9):1298-305
pubmed: 17805419
Environ Int. 2019 Aug;129:343-353
pubmed: 31150976
Environ Int. 2018 Apr;113:50-54
pubmed: 29421407
Reprod Toxicol. 2015 Jan;51:133-44
pubmed: 25543169
Environ Health Perspect. 2010 Feb;118(2):222-8
pubmed: 20123620
Mol Cell. 1999 Mar;3(3):397-403
pubmed: 10198642
J Expo Sci Environ Epidemiol. 2019 Mar;29(2):172-182
pubmed: 30482936
Int J Environ Res Public Health. 2016 Jan 20;13(1):
pubmed: 26805861
Toxicology. 2012 Mar 11;293(1-3):1-15
pubmed: 22266392
J Environ Monit. 2012 Aug;14(8):2121-6
pubmed: 22699773
Toxicol Sci. 2008 Mar;102(1):3-14
pubmed: 18003598
Clin Liver Dis. 2018 Feb;22(1):201-211
pubmed: 29128057
Toxicology. 2009 Feb 4;256(1-2):65-74
pubmed: 19059455
Sci Rep. 2019 Jun 24;9(1):9179
pubmed: 31235847
Sci Rep. 2017 Feb 27;7:43380
pubmed: 28240244
J Nutr. 1989 Dec;119(12):1880-92
pubmed: 2576038
PLoS Biol. 2010 Jun 29;8(6):e1000412
pubmed: 20613859
Environ Res. 2017 May;155:15-21
pubmed: 28171771
Environ Res. 2016 Apr;146:299-307
pubmed: 26796985
Toxicol Rep. 2015 Jun 30;2:939-949
pubmed: 28962433
Neurotoxicology. 2017 Jan;58:110-119
pubmed: 27888120
Arch Environ Occup Health. 2021;76(1):12-22
pubmed: 32102626
Toxicol Appl Pharmacol. 2020 Oct 15;405:115204
pubmed: 32822737
Environ Health Perspect. 2010 Feb;118(2):229-33
pubmed: 20123605
Rapid Commun Mass Spectrom. 2006;20(18):2728-34
pubmed: 16915561
Environ Health Perspect. 2020 Apr;128(4):47005
pubmed: 32271623
Environ Health Perspect. 2014 Oct;122(10):1040-51
pubmed: 24968389
Environ Int. 2019 Sep;130:104874
pubmed: 31200157
Environ Pollut. 2019 Apr;247:1055-1063
pubmed: 30823334
BMJ. 2014 Jul 29;349:g4596
pubmed: 25239614
Arch Toxicol. 2020 Jun;94(6):2131-2147
pubmed: 32227269
Environ Health Perspect. 2019 Aug;127(8):87006
pubmed: 31433236
J Clin Endocrinol Metab. 2020 Mar 1;105(3):
pubmed: 31665456
J Occup Environ Med. 2006 Aug;48(8):759-70
pubmed: 16902368
Mol Cell Endocrinol. 2009 May 25;304(1-2):97-105
pubmed: 19433254
Toxicol Lett. 2018 Jul;291:51-60
pubmed: 29601859
J Agric Food Chem. 2020 Jan 15;68(2):633-641
pubmed: 31891488
Environ Health Perspect. 2011 Aug;119(8):1070-6
pubmed: 21501981
Environ Res. 2019 Sep;176:108540
pubmed: 31252203
PLoS One. 2019 Jan 4;14(1):e0210110
pubmed: 30608957
Environ Health Perspect. 2012 May;120(5):668-73
pubmed: 22306490
Environ Res. 2019 Apr;171:452-469
pubmed: 30739020
Environ Sci Technol. 2015 Oct 20;49(20):12306-14
pubmed: 26393377
PLoS One. 2013;8(2):e56969
pubmed: 23441227
Occup Environ Med. 2018 Jan;75(1):46-51
pubmed: 29133598
Chemosphere. 2019 Oct;233:25-33
pubmed: 31163305
Environ Health Perspect. 2013 Aug;121(8):900-5
pubmed: 23735465
Clin J Am Soc Nephrol. 2018 Oct 8;13(10):1479-1492
pubmed: 30213782
Environ Res. 2019 May;172:81-88
pubmed: 30776734
Environ Health. 2015 Jul 10;14:60
pubmed: 26159541
Integr Environ Assess Manag. 2011 Oct;7(4):513-41
pubmed: 21793199
Sci Total Environ. 2020 Jul 15;726:138498
pubmed: 32305757
Am J Gastroenterol. 2010 Jun;105(6):1354-63
pubmed: 20010922
Environ Int. 2019 Mar;124:462-472
pubmed: 30684804
Environ Health Perspect. 2016 Jul;124(7):935-42
pubmed: 26517287
Environ Toxicol Chem. 2021 Mar;40(3):543-549
pubmed: 32452041
Environ Sci Technol. 2017 Oct 3;51(19):11380-11389
pubmed: 28885018
Toxicol Sci. 2011 Jul;122(1):134-45
pubmed: 21482639
Environ Health. 2015 Nov 21;14:89
pubmed: 26590127
Environ Sci Technol. 2018 Jul 17;52(14):7972-7980
pubmed: 29897239
Environ Sci Process Impacts. 2019 Nov 1;21(11):1908-1914
pubmed: 31332417
Epidemiology. 2014 Mar;25(2):255-64
pubmed: 24407430
Ann Pediatr Endocrinol Metab. 2017 Mar;22(1):6-14
pubmed: 28443254
Environ Health Perspect. 2019 Dec;127(12):127005
pubmed: 31841032
Arch Toxicol. 2018 Jan;92(1):359-369
pubmed: 28864880
Environ Res. 2020 Feb;181:108923
pubmed: 31759646
Gene. 2017 Jul 30;622:67-71
pubmed: 28431976
J Lipid Res. 1985 Sep;26(9):1015-35
pubmed: 3906008
Environ Res. 2017 Aug;157:87-95
pubmed: 28528142
Environ Int. 2020 Jan;134:105284
pubmed: 31707300
Comput Struct Biotechnol J. 2019 Dec 17;18:93-99
pubmed: 31934310
Environ Res. 2014 Aug;133:338-47
pubmed: 25019470
Toxicol Sci. 2006 Apr;90(2):510-8
pubmed: 16415327
Environ Sci Technol. 2018 Jun 19;52(12):7101-7110
pubmed: 29758986
Curr Environ Health Rep. 2018 Jun;5(2):213-224
pubmed: 29737463
Toxicol In Vitro. 2020 Feb;62:104700
pubmed: 31676336
Environ Int. 2020 Jun;139:105686
pubmed: 32278886
Environ Res. 2013 Feb;121:95-103
pubmed: 23266098
Medicine (Baltimore). 2018 Sep;97(37):e12390
pubmed: 30213007
Endocrine. 2020 Mar;67(3):678-684
pubmed: 31565782
Environ Res. 2016 May;147:399-404
pubmed: 26950028
Environ Health Perspect. 2016 Jan;124(1):126-32
pubmed: 26090912
Toxicol Sci. 2014 Mar;138(1):76-88
pubmed: 24284791
Toxicology. 2013 Feb 8;304:185-91
pubmed: 23287389
J Am Soc Nephrol. 2008 Dec;19(12):2407-13
pubmed: 18799720
Biochim Biophys Acta. 2012 Jul;1820(7):1092-101
pubmed: 22484034
Environ Health Perspect. 2010 Feb;118(2):197-202
pubmed: 20123614
Environ Int. 2020 Jan;134:105259
pubmed: 31733527
Environ Health Perspect. 2019 Jan;127(1):17006
pubmed: 30676078
Environ Health Perspect. 2012 Jul;120(7):1036-41
pubmed: 22453676
Environ Int. 2019 Feb;123:390-398
pubmed: 30622063
Environ Toxicol Chem. 2017 Jun;36(6):1411-1421
pubmed: 28543973
Curr Environ Health Rep. 2019 Sep;6(3):80-94
pubmed: 31134516
Chemosphere. 2017 Jul;178:378-383
pubmed: 28340460
Environ Res. 2018 Jan;160:518-523
pubmed: 29106950
Reprod Toxicol. 2012 Jul;33(4):546-551
pubmed: 22107727
Toxicol Lett. 2009 Oct 28;190(2):163-71
pubmed: 19616083
J Occup Environ Med. 2007 Oct;49(10):1086-96
pubmed: 18000414
J Endocrinol Invest. 2020 May;43(5):641-652
pubmed: 31776969
Environ Sci Technol. 2019 May 7;53(9):4717-4727
pubmed: 30993978
Environ Sci Pollut Res Int. 2013 Nov;20(11):8031-44
pubmed: 23764977
Am J Epidemiol. 2011 Oct 15;174(8):893-900
pubmed: 21873601
Environ Res. 2019 Jul;174:143-151
pubmed: 31077989
Toxicol Sci. 2006 Jan;89(1):93-107
pubmed: 16221955
Am J Epidemiol. 2009 Nov 15;170(10):1268-78
pubmed: 19846564
Arch Toxicol. 2016 Mar;90(3):701-15
pubmed: 25827101
Environ Health Perspect. 2020 Feb;128(2):27006
pubmed: 32074459
J Endocrinol. 2014 Jun;221(3):R87-R103
pubmed: 24648121
Toxicol Sci. 2016 Sep;153(1):198-211
pubmed: 27413105
Environ Res. 2014 Jan;128:78-83
pubmed: 24299613
Regul Toxicol Pharmacol. 2018 Nov;99:168-181
pubmed: 30240830
Environ Sci Technol. 2014 May 6;48(9):4637-48
pubmed: 24762048
Chemosphere. 2020 Mar;242:125208
pubmed: 31896193
Environ Res. 2018 Aug;165:317-321
pubmed: 29777922
Environ Health Perspect. 2010 May;118(5):686-92
pubmed: 20089479
Environ Int. 2013 Jul;57-58:2-10
pubmed: 23624243
Toxicol Rep. 2016;3:46-54
pubmed: 26942110
Environ Sci Technol. 2017 Sep 5;51(17):9930-9939
pubmed: 28759222
Environ Health Perspect. 2013 Mar;121(3):318-23
pubmed: 23308854
Sci Rep. 2013;3:2174
pubmed: 23846197
J Occup Environ Med. 2007 Aug;49(8):872-9
pubmed: 17693785
Environ Int. 2017 Feb;99:15-28
pubmed: 27884404
Environ Sci Technol. 2020 Mar 17;54(6):3428-3436
pubmed: 32092270
Environ Epidemiol. 2018 Sep;2(3):
pubmed: 30298140
J Clin Endocrinol Metab. 2014 Apr;99(4):E608-14
pubmed: 24606078
Environ Int. 2013 Sep;59:354-62
pubmed: 23892228
PLoS One. 2016 May 12;11(5):e0155190
pubmed: 27171144
Environ Sci Technol. 2011 Oct 1;45(19):8037-45
pubmed: 21469664
Ecotoxicol Environ Saf. 2014 Aug;106:246-52
pubmed: 24863755
J Immunotoxicol. 2017 Dec;14(1):39-49
pubmed: 28091126
Epidemiology. 2012 May;23(3):386-92
pubmed: 22370857
Environ Int. 2020 May;138:105656
pubmed: 32222612
Environ Health Perspect. 2014 Oct;122(10):1015-27
pubmed: 24968374
Toxicology. 2017 Jul 15;387:95-107
pubmed: 28558994
Environ Toxicol Chem. 2003 Nov;22(11):2639-49
pubmed: 14587903
Adv Exp Med Biol. 2018;1065:471-488
pubmed: 30051402
Arch Toxicol. 2020 May;94(5):1673-1686
pubmed: 32253466
Environ Int. 2014 Jan;62:104-12
pubmed: 24189199
Environ Sci Technol. 2016 Nov 1;50(21):11984-11993
pubmed: 27668830
Environ Health Perspect. 2019 Nov;127(11):117002
pubmed: 31714155
Reprod Toxicol. 2012 Jul;33(4):410-418
pubmed: 22120428
Environ Health Perspect. 2017 Jul 26;125(7):077018
pubmed: 28749778
Environ Health. 2020 Jan 13;19(1):5
pubmed: 31931806
Environ Res. 2015 Nov;143(Pt A):33-8
pubmed: 26432473
Toxicology. 2011 Oct 9;288(1-3):8-17
pubmed: 21723365
Environ Health Perspect. 2017 Oct 02;125(10):107001
pubmed: 28974480
Epidemiology. 2009 Nov;20(6):921-8
pubmed: 19797969
Toxicol Sci. 2019 Apr 1;168(2):519-534
pubmed: 30657992
Toxicol Sci. 2018 May 1;163(1):293-306
pubmed: 29462473
Environ Health Perspect. 2016 Aug;124(8):1227-33
pubmed: 26978841
Environ Health Perspect. 2014 Dec;122(12):1299-305
pubmed: 25260175
J Occup Environ Med. 2019 Apr;61(4):293-302
pubmed: 30589657
Am J Epidemiol. 2009 Oct 1;170(7):837-46
pubmed: 19692329
Environ Pollut. 2019 Nov;254(Pt B):113061
pubmed: 31454574
Reprod Toxicol. 2015 Jul;54:26-36
pubmed: 25499722
Environ Health Perspect. 2014 Oct;122(10):1028-39
pubmed: 24968388
Arch Environ Contam Toxicol. 2009 Feb;56(2):338-49
pubmed: 18661093
Toxicology. 2006 Oct 3;227(1-2):156-64
pubmed: 16978759
Sci Rep. 2018 Aug 6;8(1):11735
pubmed: 30082907
Environ Health. 2020 Apr 22;19(1):42
pubmed: 32321520
Toxicol Sci. 2007 Mar;96(1):133-44
pubmed: 17132714
Reprod Toxicol. 2017 Mar;68:164-170
pubmed: 27421579
PLoS One. 2012;7(6):e39255
pubmed: 22723977
Am J Epidemiol. 2013 Jun 1;177(11):1255-62
pubmed: 23552989
Environ Sci Technol. 2019 Dec 3;53(23):13970-13980
pubmed: 31661253
Toxicol Pathol. 2015 Jun;43(4):546-57
pubmed: 25326589
Cells. 2019 Dec 19;9(1):
pubmed: 31861598
Environ Health Perspect. 2015 Jan;123(1):57-63
pubmed: 25127343
Reprod Toxicol. 2009 Jun;27(3-4):365-372
pubmed: 19429407
Toxicol Sci. 2008 Nov;106(1):162-71
pubmed: 18713766
J Clin Endocrinol Metab. 2014 Jun;99(6):2173-80
pubmed: 24606077
Sci Total Environ. 2018 Jun 1;625:566-574
pubmed: 29291571
Nat Rev Dis Primers. 2018 Oct 5;4(1):29
pubmed: 30291251
Environ Int. 2017 May;102:207-212
pubmed: 28283302
Ecotoxicol Environ Saf. 2019 Jan 15;167:29-35
pubmed: 30292973
Toxicology. 2013 Apr 5;306:169-75
pubmed: 23470359
Environ Pollut. 2016 May;212:519-524
pubmed: 26970855
Pediatr Res. 2020 May;87(6):1093-1099
pubmed: 31835271
J Expo Sci Environ Epidemiol. 2019 Mar;29(2):131-147
pubmed: 30470793
Sci Total Environ. 2015 Apr 15;512-513:364-370
pubmed: 25638651
Toxicol Rep. 2020 Jan 02;7:125-132
pubmed: 31938689
Metabolomics. 2019 Jun 21;15(7):95
pubmed: 31227916
Environ Res. 2014 Jul;132:62-9
pubmed: 24742729
Environ Int. 2016 Sep;94:687-694
pubmed: 27453094
Environ Health Perspect. 2019 Oct;127(10):107003
pubmed: 31596611
Basic Clin Pharmacol Toxicol. 2008 Jul;103(1):1-8
pubmed: 18373647
Annu Rev Nutr. 2006;26:45-73
pubmed: 16848700
Toxicol Sci. 2007 Jun;97(2):595-613
pubmed: 17383973
Chem Res Toxicol. 2012 Jan 13;25(1):35-46
pubmed: 21985250
Occup Environ Med. 2015 May;72(5):373-80
pubmed: 25601914
Sci Rep. 2014 Apr 03;4:4582
pubmed: 24694979
Toxicology. 2012 Mar 11;293(1-3):16-29
pubmed: 22245121
Curr Opin Crit Care. 2019 Dec;25(6):539-549
pubmed: 31524719
Environ Health Perspect. 2008 Aug;116(8):1047-55
pubmed: 18709148
Toxicology. 2002 Jul 15;176(3):175-85
pubmed: 12093614
Toxicology. 2016 Jul 29;366-367:32-42
pubmed: 27528273
Environ Int. 2018 Dec;121(Pt 1):591-599
pubmed: 30308470
J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):16-26
pubmed: 21397692
Environ Health. 2015 Sep 29;14:79
pubmed: 26420011
Toxicology. 2017 Mar 01;378:37-52
pubmed: 28049043
J Neuroendocrinol. 2020 May;32(5):e12848
pubmed: 32307816
Toxicol Sci. 2007 Oct;99(2):366-94
pubmed: 17519394
Reprod Toxicol. 2009 Jun;27(3-4):319-330
pubmed: 19162172
Environ Int. 2020 Aug;141:105789
pubmed: 32408216