Low immune response rate of HIV-infected patients to a single injection of hepatitis A vaccine.
Adult
CD4 Lymphocyte Count
/ methods
CD4-CD8 Ratio
/ methods
Disease Outbreaks
HIV Infections
/ immunology
Hepatitis A
/ epidemiology
Hepatitis A Antibodies
/ blood
Hepatitis A Vaccines
/ administration & dosage
Humans
Immunity
/ immunology
Immunization Schedule
Middle Aged
Retrospective Studies
Viral Load
Disease outbreak
HIV infection
Hepatitis A
Hepatitis A antibodies
Immune response
Vaccine
Journal
Infectious diseases now
ISSN: 2666-9919
Titre abrégé: Infect Dis Now
Pays: France
ID NLM: 101775152
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
29
03
2020
revised:
01
04
2020
accepted:
24
09
2020
pubmed:
7
10
2020
medline:
8
9
2021
entrez:
6
10
2020
Statut:
ppublish
Résumé
We aimed to evaluate the immune response of HIV-1 positive patients to a single injection of HAV vaccine in a context of vaccine shortage during the 2017 European outbreak. We retrospectively enrolled all HIV-1 positive patients vaccinated by a single injection of HAV vaccine Vaqta 50®. HAV serology was performed before and>30 days after the vaccine injection. Among the 73 patients, HIV-1 viral load was≤50 copies/mL in 93.2% of the cases. Medians of CD4 and median ratio of T CD4/CD8 cells were 658/mm A serologic control should be recommended in this population in the event of a single injection vaccination schedule. During routine follow-up, and prior to any untoward event, physicians should assess the vaccination coverage of HIV-infected patients.
Identifiants
pubmed: 33022294
pii: S0399-077X(20)30714-9
doi: 10.1016/j.medmal.2020.09.016
pii:
doi:
Substances chimiques
Hepatitis A Antibodies
0
Hepatitis A Vaccines
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
94-96Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.