The Role of Phosphatidylinositol Phosphate Kinases during Viral Infection.


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
03 10 2020
Historique:
received: 11 09 2020
revised: 27 09 2020
accepted: 29 09 2020
entrez: 7 10 2020
pubmed: 8 10 2020
medline: 9 3 2021
Statut: epublish

Résumé

Phosphoinositides account for only a small proportion of cellular phospholipids, but have long been known to play an important role in diverse cellular processes, such as cell signaling, the establishment of organelle identity, and the regulation of cytoskeleton and membrane dynamics. As expected, given their pleiotropic regulatory functions, they have key functions in viral replication. The spatial restriction and steady-state levels of each phosphoinositide depend primarily on the concerted action of specific phosphoinositide kinases and phosphatases. This review focuses on a number of remarkable examples of viral strategies involving phosphoinositide kinases to ensure effective viral replication.

Identifiants

pubmed: 33022924
pii: v12101124
doi: 10.3390/v12101124
pmc: PMC7599803
pii:
doi:

Substances chimiques

Caenorhabditis elegans Proteins 0
Phosphatidylinositol Phosphates 0
Phosphatidylinositols 0
Phosphotransferases EC 2.7.-
PPK-3 protein, C elegans EC 2.7.1.-
Phosphotransferases (Alcohol Group Acceptor) EC 2.7.1.-
Phosphoric Monoester Hydrolases EC 3.1.3.2

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Anne Beziau (A)

INSERM U1259, University of Tours, 37000 Tours, France.

Denys Brand (D)

INSERM U1259, University of Tours, 37000 Tours, France.
Virology Laboratory, Tours University Hospital, 3700 Tours, France.

Eric Piver (E)

INSERM U1259, University of Tours, 37000 Tours, France.
Biochemistry and Molecular Biology, Tours University Hospital, 3700 Tours, France.

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Classifications MeSH