Short Time to Market and Forward Planning Will Enable Cell Therapies to Deliver R&D Pipeline Value.

autologous cell therapy cost of development cost of goods oncology cell therapy pipeline value

Journal

Human gene therapy
ISSN: 1557-7422
Titre abrégé: Hum Gene Ther
Pays: United States
ID NLM: 9008950

Informations de publication

Date de publication:
May 2021
Historique:
pubmed: 8 10 2020
medline: 1 2 2022
entrez: 7 10 2020
Statut: ppublish

Résumé

There is considerable industry excitement about the curative potential of cell and gene therapies, but significant challenges remain in designing cost-effective treatments that are accessible globally. We have taken a modeling-based approach to define the cost and value drivers for cell therapy assets during pharmaceutical drug development. We have created a model development program for a lentiviral modified

Identifiants

pubmed: 33023309
doi: 10.1089/hum.2020.212
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

433-445

Auteurs

Delfi Krishna (D)

GlaxoSmithKline Pharmaceutical Research and Development, Collegeville, Pennsylvania, USA.

Laure Rittié (L)

GlaxoSmithKline Pharmaceutical Research and Development, Collegeville, Pennsylvania, USA.

Hoang Tran (H)

GlaxoSmithKline Pharmaceutical Research and Development, Collegeville, Pennsylvania, USA.

Xuan Zheng (X)

GlaxoSmithKline Pharmaceutical Research and Development, Collegeville, Pennsylvania, USA.

Chia-En Chen-Rogers (CE)

GlaxoSmithKline Pharmaceutical Research and Development, Collegeville, Pennsylvania, USA.

Amanda McGillivray (A)

GlaxoSmithKline Pharmaceutical Research and Development, Collegeville, Pennsylvania, USA.

Timothy Clay (T)

GlaxoSmithKline Pharmaceutical Research and Development, Collegeville, Pennsylvania, USA.

Amol Ketkar (A)

GlaxoSmithKline Pharmaceutical Research and Development, Collegeville, Pennsylvania, USA.

Joseph Tarnowski (J)

GlaxoSmithKline Pharmaceutical Research and Development, Collegeville, Pennsylvania, USA.

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Classifications MeSH