More Severe Hypercoagulable State in Acute COVID-19 Pneumonia as Compared With Other Pneumonia.
CFT, clot formation time
COVID-19, coronavirus disease 2019
CT, clotting time
MCF, maximum clot firmness
SARS-CoV-2, severe acute respiratory syndrome coronavirus 2
Journal
Mayo Clinic proceedings. Innovations, quality & outcomes
ISSN: 2542-4548
Titre abrégé: Mayo Clin Proc Innov Qual Outcomes
Pays: Netherlands
ID NLM: 101728275
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
pubmed:
8
10
2020
medline:
8
10
2020
entrez:
7
10
2020
Statut:
ppublish
Résumé
To conduct a comprehensive evaluation of coagulation profiles-via traditional and whole blood thromboelastometry tests-in coronavirus disease 2019 (COVID-19)-positive vs COVID-19-negative patients admitted to medical wards for acute pneumonia. We enrolled all consecutive patients admitted to internal medicine wards of Padova University Hospital between 7 March and 30 April, 2020, for COVID-19-related pneumonia (cases) vs non-COVID-19 pneumonia (controls). A group of healthy individuals acted as baseline for thromboelastometry parameters. Fifty-six cases (mean age, 64±15 years; male/female, 37/19) and 56 controls (mean age, 76±11 years; male/female, 35/21) were enrolled. Cases and controls exhibited markedly hypercoagulable thromboelastometry profiles vs healthy individuals, mainly characterized by a significantly shorter propagation phase of coagulation (clot formation time) and significantly increased maximum clot firmness ( Patients admitted to internal medicine wards for COVID-19 pneumonia presented a markedly prothrombotic state, which seems peculiar to COVID-19 rather than pneumonia itself.
Identifiants
pubmed: 33024937
doi: 10.1016/j.mayocpiqo.2020.09.002
pii: S2542-4548(20)30185-5
pmc: PMC7528900
doi:
Types de publication
Journal Article
Langues
eng
Pagination
696-702Informations de copyright
© 2020 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc.
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