Artificial oral fluid characterisation: Potential for use as a reference matrix in drug testing.
AOF
drug screening
quality assurance samples
reference matrix
Journal
Drug testing and analysis
ISSN: 1942-7611
Titre abrégé: Drug Test Anal
Pays: England
ID NLM: 101483449
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
09
04
2020
revised:
22
09
2020
accepted:
24
09
2020
pubmed:
8
10
2020
medline:
29
10
2021
entrez:
7
10
2020
Statut:
ppublish
Résumé
Quality assurance schemes for drug-screening programmes require access to large quantities of biological matrices for reference or control samples. This presents problems when the availability of a matrix, such as oral fluid (OF) for screening or for confirmatory purposes, limits the collection of large volumes. In such cases, synthetic alternatives of OF may provide a solution. The preparation of an artificial (synthetic) oral fluid (AOF) was conducted by dissolving its components (salts, surfactant, antimicrobial agent and mucin) in water. We characterised the physical properties of AOF to determine its suitability as a matrix for quality assurance purposes. The evaluation of pH, specific gravity (SG), conductivity (mS cm
Substances chimiques
Anti-Infective Agents
0
Mucins
0
Salts
0
Surface-Active Agents
0
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
709-719Subventions
Organisme : Home Office Centre for Applied Science and Technology
ID : HOS/13/038
Informations de copyright
© 2020 The Authors. Drug Testing and Analysis published by John Wiley & Sons Ltd.
Références
Choo RE, Huestis MA. Oral fluid as a diagnostic tool. Clin Chem Lab Med. 2004;42(11):1273-1287.
Drummer OH, Verstraete A. Special edition of forensic science international detection of drugs in oral fluid. Forensic Sci Int. 2005;150(2-3):117-117.
Drummer OH. Introduction and review of collection techniques and applications of drug testing of oral fluid. Ther Drug Monit. 2008;30(2):203-206.
Vindenes V, Lund HME, Andresen W, et al. Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers. Forensic Sci Int. 2012;219(1-3):165-171.
Dyer KR, Wilkinson C. The detection of illicit drugs in oral fluid: another potential strategy to reduce illicit drug-related harm. Drug Alcohol Rev. 2008;27(1):99-107.
Mehta N, Kunkel F, Shaparin N, Stripp R, Borg D, Fey E. Can oral fluid replace urine and blood drug testing as the gold standard in the pain management industry? J Pain. 2015;16(4):S7-S7.
Chiappin S, Antonelli G, Gatti R, De Palo EF. Saliva specimen: a new laboratory tool for diagnostic and basic investigation. Clin Chim Acta. 2007;383(1-2):30-40.
Wolff K, Agombar R, Clatworthy A, et al. Expert Panel on drug driving: Alternative matrices for confirmatory testing. Department for Transport. In: SB-2988 RR, ed2017. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/624915/expert-panel-report.pdf. Accessed July 17, 2020.
Crouch DJ, Walsh JM, Flegel R, Cangianelli L, Baudys J, Atkins R. An evaluation of selected oral fluid point-of-collection drug-testing devices. J Anal Tox. 2005;29(4):244-248.
Gjerde H, Langel K, Favretto D, Verstraete AG. Detection of illicit drugs in oral fluid from drivers as biomarker for drugs in blood. Forensic Sci Int. 2015;256:42-45.
Milanowski M, Pomastowski P, Ligor T, Buszewski B. Saliva-volatile biomarkers and profiles. Crit Rev Anal Chem. 2017;47(3):251-266.
Veerman ECI, Valentijnbenz M, Amerongen AVN. Viscosity of human salivary mucins-effect of pH and ionic-strength and role of sialic-acid. J Biol Buccale. 1989;17(4):297-306.
Sandberg T, Carlsson J, Ott MK. Interactions between human neutrophils and mucin-coated surfaces. J Mater Sci-Mater M. 2009;20(2):621-631.
Berg CH, Lindh L, Arnebrant T. Intraoral lubrication of PRP-1, statherin and mucin as studied by AFM. Biofouling. 2004;20(1):65-70.
Gohara K, Ansai T, Koseki T, et al. A new automatic device for measuring the spinnbarkeit of saliva: the Neva Meter. J Dent. 2004;32(4):335-338.
Food and Drug Administration Office of Regulatory Affairs ORA Laboratory Manual Volume II. https://www.fda.gov/media/73979/download. Accessed July 14, 2020.
Li-Hui W, Chuan-Quan L, Long Y, Ru-Liu L, Long-Hui C, Wei-Wen C. Gender differences in the saliva of young healthy subjects before and after citric acid stimulation. Clin Chim Acta. 2016;460:142-145.
Dawes C. Circadian-rhythms in human salivary flow-rate and composition. J Physiol-London. 1972;220(3):529-545.
Dawes C, Jenkins GN. Effects of different stimuli on composition of saliva in man. J Physiol-London. 1964;170(1):86-100.
Proctor GB. The physiology of salivary secretion. Periodontol 20002000. 2016;70(1):11-25.
Hopcraft MS, Tan C. Xerostomia: an update for clinicians. Aust Dent J. 2010;55(3):238-244.
Lopez-Pintor RM, Casanas E, Gonzalez-Serrano J, et al. Xerostomia, hyposalivation, and salivary flow in diabetes patients. J Diabetes Res. 2016:1-15.
Quock RL. Xerostomia: current streams of investigation. Or Surg or Med or pa. 2016;122(1):53-60.
Sniegoski LT, Waddell J, Welch MJ, Fatah AA. Evaluation of Oral Fluid Testing Devices https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=902366. Accessed July 13, 2020.
Fratto G, Manzon L. Use of psychotropic drugs and associated dental diseases. Int J Psychiat Med. 2014;48(3):185-197.
Glare P, Walsh D, Sheehan D. The adverse effects of morphine: a prospective survey of common symptoms during repeated dosing for chronic cancer pain. Am J Hosp Palliat Care. 2006;23(3):229-235.
Thomson WM, Poulton R, Broadbent JM, Al-Kubaisy S. Xerostomia and medications among 32-year-olds. Acta Odontol Scand. 2006;64(4):249-254.
Smidt D, Torpet LA, Nauntofte B, Heegaard KM, Pedersen AML. Associations between oral and ocular dryness, labial and whole salivary flow rates, systemic diseases and medications in a sample of older people. Commun Dent Oral. 2011;39(3):276-288.
Affoo RH, Foley N, Garrick R, Siqueira WL, Martin RE. Meta-analysis of salivary flow rates in young and older adults. J Am Geriatr Soc. 2015;63(10):2142-2151.
Centre for Applied Science and Technology. Preliminary Drug Testing Devices: A Guide to Type Approval Procedures for Drug Testing Devices Used for Transport Law Enforcement in Great Britain, Test Solution Matrix. 2012. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/190174/Guide_to_Type_Approval_Preliminary_Drug_Testing_Devices__2_.pdf. Accessed July 17, 2020.
Gal JY, Fovet Y, Adib-Yadzi M. About a synthetic saliva for in vitro studies. Talanta. 2001;53(6):1103-1115.
Manosroi A, Pattamapun K, Khositsuntiwong N, et al. Physicochemical properties and biological activities of Thai plant mucilages for artificial saliva preparation. Pharm Biol. 2015;53(11):1653-1660.
Lapiedra RC, Gomez GE, Sanchez BP, Pereda AA, Turner MD. The effect of a combination saliva substitute for the management of xerostomia and hyposalivation. J Maxillofac Oral Surg. 2015;14(3):653-658.
Skrinjar I, Vucicevic Boras V, Bakale I, et al. Comparison between three different saliva substitutes in patients with hyposalivation. Clin Oral Investig. 2015;19(3):753-757.
Mystkowska J, Car H, Dabrowski JR, Romanowska J, Klekotka M, Milewska AJ. Artificial mucin-based saliva preparations-physicochemical and tribological properties. Oral Health Prev Dent. 2018;16(2):183-193.
Pillai K, Akhter J, Mekkawy A, Chua TC, Morris DL. Physical and chemical characteristics of mucin secreted by pseudomyxoma peritonei (PMP). Int J Med Sci. 2017;14(1):18-28.
Tettamanti G, Pigman W. Purification and characterization of bovine and ovine submaxillary mucins. Arch Biochem Biophys. 1968;124(1-3):41-50.
Nisizawa K, Pigman W. Purification of a glycoprotein from bovine-submaxillary glands. Biochem J. 1960;75:293-298.
Nisizawa K, Pigman W. The composition and properties of the mucin clot from cattle submaxillary glands. Arch Oral Biol. 1959;1(2):161-170.
Lichstein HC, Soule MH. Studies of the effect of sodium azide on microbic growth and respiration I the action of sodium azide on microbic growth. J Bacteriol. 1944;47(3):221-230.
https://www.sigmaaldrich.com/life-science/biochemicals/biochemical-products.html? TablePage=111264510. Accessed July 15, 2020.
FDA. Pharmaceutical Microbiology Manual 2014 ORA ORA.007, Version 1.2. https://www.fda.gov/files/about%20fda/published/Pharmaceutical-Microbiology-Manual.pdf. Accessed July 17, 2020.
Stepto RFT. Dispersity in polymer science. Pure Appl Chem. 2009;81(2):351-353.
Guyton AC, Hall JE. Textbook of Medical Physiology. 13th ed. Philadelphia: W.B. Saunders; 2015.
Rai B. Oral fluid in toxicology. Intern J Toxicol. 2006;3(2):1-6.
Gittings S, Turnbull N, Henry B, Roberts CJ, Gershkovich P. Characterisation of human saliva as a platform for oral dissolution medium development. Eur J Pharm Biopharm. 2015;91:16-24.
Foglio-Bonda A, Pattarino F, Foglio-Bonda PL. Kinematic viscosity of unstimulated whole saliva in healthy young adults. Eur Rev Med Pharmacol. 2014;18(20):2988-2994.
Sandberg T, Blom H, Caldwell KD. Potential use of mucins as biomaterial coatings. I. Fractionation, characterization, and model adsorption of bovine, porcine, and human mucins. J Biomed Mater Res a. 2009;91A(3):762-772.
Echipare L, Harju Z. Libre Texts https://chem.libretexts.org/Bookshelves/Physical_and_Theoretical_Chemistry_Textbook_Maps/Supplemental_Modules_(Physical_and_Theoretical_Chemistry)/Physical_Properties_of_Matter/Solutions_and_Mixtures/Colligative_Properties/Freezing_Point_Depression. Accessed June 12, 2019.
Yoshimura H, Matsumoto S, Matsumoto F, Inoue T. Mineral composition in resting saliva as compared with that in saliva secreted by stimulation: 1. Physiol Soc Jap. 1963;25(9):441-450.
Lentner C. Thermal Properties of Tissues. In: Diem K, Ciba-Geigy LC, eds. Geigy Scientific Tables. Vol.7 Switzerland: Basel; 1975:36.
Raut AS, Kalonia DS. Pharmaceutical perspective on opalescence and liquid-liquid phase separation in protein solutions. Mol Pharm. 2016;13(5):1431-1444.
Winder CL, Al-Adham ISI, Malek S, Buultjens TEJ, Horrocks AJ, Collier PJ. Outer membrane protein shifts in biocide-resistant Pseudomonas aeruginosa PAO1. J Appl Microbiol. 2000;89(2):289-295.
Whembolua GLS, Granger DA, Singer S, Kivlighan KT, Marguin JA. Bacteria in the oral and its effects on the measurement of cortisol, dehydroepiandrosterone, and testosterone in saliva. Horm Behav. 2006;49(4):478-483.