In vivo sun protection factor and UVA protection factor determination using (hybrid) diffuse reflectance spectroscopy and a multi-lambda-LED light source.

SPF determination by HDRS fiber probe non-erythemal testing non-invasive sunscreen

Journal

Journal of biophotonics
ISSN: 1864-0648
Titre abrégé: J Biophotonics
Pays: Germany
ID NLM: 101318567

Informations de publication

Date de publication:
02 2021
Historique:
received: 01 09 2020
revised: 29 09 2020
accepted: 29 09 2020
pubmed: 8 10 2020
medline: 13 7 2021
entrez: 7 10 2020
Statut: ppublish

Résumé

The sun protection factor (SPF) values are currently determined using an invasive procedure, in which the volunteers are irradiated with ultraviolet (UV) light. Non-invasive approaches based on hybrid diffuse reflectance spectroscopy (HDRS) have shown a good correlation with conventional SPF testing. Here, we present a novel compact and adjustable DRS test system. The in vivo measurements were performed using a multi-lambda-LED light source and an 84-channel imaging spectrograph with a fiber optic probe for detection. A transmission spectrum was calculated based on the reflectance measured with sunscreen and the reflectance measured without sunscreen. The preexposure in vitro spectrum was fitted to the in vivo spectrum. Each of the 11 test products was investigated on 10 volunteers. The SPF and UVA-PF values obtained by this new approach were compared with in vivo SPF results determined by certified test institutes. A correlation coefficient R

Identifiants

pubmed: 33025740
doi: 10.1002/jbio.202000348
doi:

Substances chimiques

Sunscreening Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202000348

Informations de copyright

© 2020 The Authors. Journal of Biophotonics published by Wiley-VCH GmbH.

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Auteurs

Carolin Maria Throm (CM)

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venereology and Allergology, Berlin, Germany.

Georg Wiora (G)

Courage+Khazaka electronic GmbH, Cologne, Germany.

Carina Reble (C)

Courage+Khazaka electronic GmbH, Cologne, Germany.

Johannes Schleusener (J)

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venereology and Allergology, Berlin, Germany.

Sabine Schanzer (S)

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venereology and Allergology, Berlin, Germany.

Hans Karrer (H)

Hans Karrer GmbH, Augsburg, Germany.

Ludger Kolbe (L)

Beiersdorf AG, Research and Development, Hamburg, Germany.

Georg Khazaka (G)

Courage+Khazaka electronic GmbH, Cologne, Germany.

Martina C Meinke (MC)

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venereology and Allergology, Berlin, Germany.

Jürgen Lademann (J)

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology, Venereology and Allergology, Berlin, Germany.

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