Amphiphilic mannose-6-phosphate glycopolypeptide-based bioactive and responsive self-assembled nanostructures for controlled and targeted lysosomal cargo delivery.
Journal
Biomaterials science
ISSN: 2047-4849
Titre abrégé: Biomater Sci
Pays: England
ID NLM: 101593571
Informations de publication
Date de publication:
21 Nov 2020
21 Nov 2020
Historique:
pubmed:
8
10
2020
medline:
15
5
2021
entrez:
7
10
2020
Statut:
ppublish
Résumé
Receptors of carbohydrate mannose-6-phosphate (M6P) are overexpressed in specific cancer cells (such as breast cancer) and are also involved in the trafficking of mannose-6-phosphate labeled proteins exclusively onto lysosomes via cell surface M6P receptor (CI-MPR) mediated endocytosis. Herein, for the first time, mannose-6-phosphate glycopolypeptide (
Substances chimiques
Mannosephosphates
0
mannose-6-phosphate
3672-15-9
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM