Salvage surgery for stage IVa thymic carcinoma combined with aortic arch resection - case report.


Journal

Journal of cardiothoracic surgery
ISSN: 1749-8090
Titre abrégé: J Cardiothorac Surg
Pays: England
ID NLM: 101265113

Informations de publication

Date de publication:
07 Oct 2020
Historique:
received: 10 08 2020
accepted: 05 10 2020
entrez: 8 10 2020
pubmed: 9 10 2020
medline: 2 3 2021
Statut: epublish

Résumé

Although complete surgical resection of thymic carcinoma is a prognostic factor, extended surgery combined with a major blood vessel procedure remains controversial because of the increased risk of mortality. We report a case of Stage IVa thymic carcinoma successfully resected with a pneumonectomy along with aortic arch replacement after chemotherapy. A 45-year-old male was diagnosed with thymic carcinoma invasion to the aortic arch and left pulmonary artery. Malignant pericardial effusion was also noted, though disappeared after chemotherapy, thus surgical options were considered. A radical resection procedure including left pneumonectomy, aortic arch replacement with total rerouting of the supra-arch vessels, and right pulmonary artery plication was performed. The postoperative course was uneventful and the patient has been disease-free for 3 years. Extended salvage surgery might be a valuable option for advanced thymic carcinoma.

Sections du résumé

BACKGROUND BACKGROUND
Although complete surgical resection of thymic carcinoma is a prognostic factor, extended surgery combined with a major blood vessel procedure remains controversial because of the increased risk of mortality. We report a case of Stage IVa thymic carcinoma successfully resected with a pneumonectomy along with aortic arch replacement after chemotherapy.
CASE PRESENTATION METHODS
A 45-year-old male was diagnosed with thymic carcinoma invasion to the aortic arch and left pulmonary artery. Malignant pericardial effusion was also noted, though disappeared after chemotherapy, thus surgical options were considered. A radical resection procedure including left pneumonectomy, aortic arch replacement with total rerouting of the supra-arch vessels, and right pulmonary artery plication was performed. The postoperative course was uneventful and the patient has been disease-free for 3 years.
CONCLUSION CONCLUSIONS
Extended salvage surgery might be a valuable option for advanced thymic carcinoma.

Identifiants

pubmed: 33028405
doi: 10.1186/s13019-020-01354-1
pii: 10.1186/s13019-020-01354-1
pmc: PMC7542946
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

305

Références

Gen Thorac Cardiovasc Surg. 2015 Mar;63(3):159-63
pubmed: 25311849
J Thorac Oncol. 2008 Jan;3(1):53-8
pubmed: 18166841
Ann Thorac Surg. 2019 Jun;107(6):e399-e401
pubmed: 30513316
Surg Case Rep. 2019 Dec 12;5(1):198
pubmed: 31832805
J Thorac Oncol. 2014 Apr;9(4):541-8
pubmed: 24736078
J Cardiothorac Surg. 2015 Oct 29;10:137
pubmed: 26515387
Ann Thorac Surg. 2017 Nov;104(5):1718-1724
pubmed: 28969896
Ann Thorac Surg. 2016 Aug;102(2):e139-41
pubmed: 27449450

Auteurs

Hiroyuki Yamato (H)

Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Soichiro Funaki (S)

Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Kazuo Shimamura (K)

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Keiwa Kin (K)

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Toru Kuratani (T)

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Yoshiki Sawa (Y)

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

Yasushi Shintani (Y)

Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan. yshintani@thoracic.med.osaka-u.ac.jp.

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