Synthesis and structure of a new thiazoline-based palladium(II) complex that promotes cytotoxicity and apoptosis of human promyelocytic leukemia HL-60 cells.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
07 10 2020
07 10 2020
Historique:
received:
26
03
2020
accepted:
02
09
2020
entrez:
8
10
2020
pubmed:
9
10
2020
medline:
15
12
2020
Statut:
epublish
Résumé
Cisplatin is one of the most widely used chemotherapeutic agents in the treatment of different tumors but has high toxicity and side effects. Therefore, the synthesis of new chemotherapeutic agents is necessary, so that they are effective in the treatment of cancer while avoiding such toxicity. In this study, we have synthesized and characterized a palladium(II) complex, [PdCl
Identifiants
pubmed: 33028870
doi: 10.1038/s41598-020-73488-0
pii: 10.1038/s41598-020-73488-0
pmc: PMC7542172
doi:
Substances chimiques
Antineoplastic Agents
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
16745Références
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