FOLLICULAR THYROID CARCINOMA - CLINICAL AND DIAGNOSTIC FINDINGS IN A 20-YEAR FOLLOW UP STUDY.
Minimally invasive
follicular carcinoma
prognosis
thyroid
widely invasive
Journal
Acta endocrinologica (Bucharest, Romania : 2005)
ISSN: 1841-0987
Titre abrégé: Acta Endocrinol (Buchar)
Pays: Romania
ID NLM: 101269720
Informations de publication
Date de publication:
Historique:
entrez:
8
10
2020
pubmed:
9
10
2020
medline:
9
10
2020
Statut:
ppublish
Résumé
Follicular thyroid carcinomas (FTC) represent 6-10 % of all thyroid carcinomas; the evolution of FTC is quite controversial, partly due to frequent changes of the histopathological definition (minimally invasive-MIFTC or widely invasive carcinoma-WIFTC) and treatment strategies adjustments. This research aims to examine the diagnostic procedure, therapeutic attitude and survival rates of patients with FTC, over a period of 16 years in the same institution, with a follow-up of at least 4 years, by analyzing correlations between histology subtype, treatments and the rate of recurrent disease. We have studied 5891 patients with thyroid carcinomas who have undergone surgical or oncological treatment within the institution, between 1 There was an unexpected high percentage of WIFTC and also an increased number of biochemically persistent and/or recurrent disease in patients with MIFTC. A stronger correlation was observed with the tumour dimensions, rather than with the histopathological subtype. This research observed that overall survival was associated with tumour size rather than histopathological subtype and there is an important need to perform further studies to assess the effectiveness of treatment strategies.
Identifiants
pubmed: 33029233
doi: 10.4183/aeb.2020.170
pii: aeb.2020.170
pmc: PMC7535902
doi:
Types de publication
Journal Article
Langues
eng
Pagination
170-177Informations de copyright
©by Acta Endocrinologica Foundation.
Références
Onco Targets Ther. 2016 Nov 07;9:6873-6884
pubmed: 27853381
Clujul Med. 2018 Oct;91(4):372-375
pubmed: 30564011
Int J Cancer. 2015 May 1;136(9):2187-95
pubmed: 25284703
Mod Pathol. 2003 May;16(5):437-44
pubmed: 12748250
Acta Endocrinol (Buchar). 2018 Jan-Mar;14(1):1-10
pubmed: 31149229
ScientificWorldJournal. 2014 Mar 04;2014:952095
pubmed: 24741369
Rom J Morphol Embryol. 2012;53(4):1007-12
pubmed: 23303025
ANZ J Surg. 2002 Nov;72(11):844-5
pubmed: 12437700
N Engl J Med. 2016 Sep 15;375(11):1054-67
pubmed: 27626519
World J Surg Oncol. 2015 Jun 04;13:193
pubmed: 26041024
Thyroid. 2013 Jun;23(6):695-702
pubmed: 23194434
Thyroid. 2016 Aug;26(8):1053-60
pubmed: 27279587
Chirurg. 2010 Jul;81(7):627-30, 632-5
pubmed: 20544166
J BUON. 2014 Apr-Jun;19(2):524-9
pubmed: 24965416
Eur J Surg Oncol. 2011 Feb;37(2):181-5
pubmed: 21144693
PLoS One. 2016 May 12;11(5):e0155489
pubmed: 27171147
Curr Radiopharm. 2013 Dec;6(4):249-52
pubmed: 24410626
Thyroid. 2015 Nov;25(11):1209-16
pubmed: 26440366
Lancet Diabetes Endocrinol. 2018 Jun;6(6):500-514
pubmed: 29102432
Clujul Med. 2017;90(3):256-261
pubmed: 28781520
Ann R Coll Surg Engl. 2017 Feb;99(2):151-154
pubmed: 27659362