Xanthogranulomatous cholecystitis: a rare gallbladder pathology from a single-center perspective.
Cholecystectomy
Gallbladder
Gallbladder neoplasms
Gallstones
Xanthogranulomatous cholecystitis
Journal
Annals of surgical treatment and research
ISSN: 2288-6575
Titre abrégé: Ann Surg Treat Res
Pays: Korea (South)
ID NLM: 101622895
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
28
04
2020
revised:
17
06
2020
accepted:
16
07
2020
entrez:
8
10
2020
pubmed:
9
10
2020
medline:
9
10
2020
Statut:
ppublish
Résumé
The aim of this study was to review patients with xanthogranulomatous cholecystitis (XGC). A total of 79 patients diagnosed with XGC were included in the study. The criteria for XGC in the pathology specimens were the presence of histiocytes, cholesterol deposits, lipids, and focal or widespread wall enlargement. Patients were diagnosed with XGC, of which 52 (65.8%) were male and 27 (34.2%) were female, creating a male-to-female ratio of 2:1. The mean age was 65.8 ± 14.3 years (range, 36-97 years). The most common presenting symptom was abdominal pain (63.3%), and the least common presenting symptom was jaundice (8.9%). Of the total, 25 patients were found to have pathological conditions with the potential to obstruct the bile duct or to slow bile flow. A frozen section examination was performed on 20 patients due to suspicion of a tumor by intraoperative macroscopic examination. However, no malignancy was detected in the cases who underwent a frozen section examination. An increase in wall thickness of the gallbladder was observed in 81.6% (n = 31) of the patients on computed tomography scans and in 81.8% (n = 18) of the patients on magnetic resonance imaging scans in which possible tumor lesions were reported, but no tumor was detected. It is difficult to diagnose XGC either preoperatively or intraoperatively, and further imaging methods are needed in the preoperative period other than ultrasonography. However, a definitive diagnosis depends exclusively on pathologic examination.
Identifiants
pubmed: 33029482
doi: 10.4174/astr.2020.99.4.230
pmc: PMC7520231
doi:
Types de publication
Journal Article
Langues
eng
Pagination
230-237Informations de copyright
Copyright © 2020, the Korean Surgical Society.
Déclaration de conflit d'intérêts
Conflict of Interest: No potential conflict of interest relevant to this article was reported.
Références
Eur J Radiol. 2010 Jun;74(3):e79-83
pubmed: 19446416
Surg Endosc. 2017 Dec;31(12):5289-5294
pubmed: 28593410
Clin Radiol. 2013 Oct;68(10):992-1001
pubmed: 23622795
Eur J Radiol. 2013 Sep;82(9):1391-7
pubmed: 23726123
Semin Liver Dis. 2003 Feb;23(1):101-6
pubmed: 12616455
Lancet Oncol. 2003 Mar;4(3):167-76
pubmed: 12623362
World J Surg. 2004 Mar;28(3):254-7
pubmed: 14961199
Radiographics. 2002 Mar-Apr;22(2):387-413
pubmed: 11896229
Ultrasound Med Biol. 2019 Nov;45(11):2925-2931
pubmed: 31447238
ANZ J Surg. 2009 Dec;79(12):946-7
pubmed: 20003001
Acta Cytol. 2000 Jul-Aug;44(4):508-14
pubmed: 10934941
Cell Biochem Biophys. 2012 Nov;64(2):131-5
pubmed: 22707297
Hepatobiliary Pancreat Dis Int. 2007 Oct;6(5):504-8
pubmed: 17897914
Abdom Imaging. 2015 Oct;40(7):2281-92
pubmed: 25952571
Eur J Pediatr. 1990 Aug;149(11):765-7
pubmed: 2121491
Arch Pathol Lab Med. 1982 Jun;106(6):302-4
pubmed: 6896437
Am J Surg Pathol. 1981 Oct;5(7):653-9
pubmed: 7337158
Arch Pathol. 1970 Nov;90(5):423-32
pubmed: 4319984
J Hepatobiliary Pancreat Surg. 2009;16(3):333-8
pubmed: 19280109
Gut Liver. 2010 Dec;4(4):518-23
pubmed: 21253302
Surg Laparosc Endosc Percutan Tech. 2009 Jun;19(3):231-3
pubmed: 19542852
Abdom Imaging. 1996 Sep-Oct;21(5):456-60
pubmed: 8832871
HPB (Oxford). 2014 May;16(5):448-58
pubmed: 23991684
Int J Cancer. 1990 May 15;45(5):821-4
pubmed: 2335386
Br J Surg. 1990 Mar;77(3):255-6
pubmed: 2182176
Hepatogastroenterology. 2009 May-Jun;56(91-92):597-601
pubmed: 19621662
Indian J Pathol Microbiol. 1989 Oct;32(4):256-60
pubmed: 2632411
Prz Gastroenterol. 2019;14(3):193-197
pubmed: 31649791