Prevalence and risk factors for atrial fibrillation in dogs with myxomatous mitral valve disease.

Animals Atrial Fibrillation / complications Cross-Sectional Studies Dog Diseases / epidemiology Dogs Male Mitral Valve / diagnostic imaging Prevalence Retrospective Studies Risk Factors
canine cardiac arrhythmia echocardiography electrocardiography epidemiology

Journal

Journal of veterinary internal medicine
ISSN: 1939-1676
Titre abrégé: J Vet Intern Med
Pays: United States
ID NLM: 8708660

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 31 10 2019
revised: 23 09 2020
accepted: 23 09 2020
pubmed: 9 10 2020
medline: 29 6 2021
entrez: 8 10 2020
Statut: ppublish

Résumé

Atrial fibrillation (AF) is a common supraventricular arrhythmia more frequently observed in large breed dogs. Estimate the prevalence of AF in dogs with myxomatous mitral valve disease (MMVD) and identify risk factors for developing AF. A total of 2194 client-owned dogs with MMVD, including 1280, 588, 290, and 36 dogs in ACVIM stages B1, B2, C, and D, respectively. Retrospective, cross-sectional study. The medical databases of 3 veterinary teaching hospitals were reviewed. Inclusion criteria were a diagnosis of MMVD after complete cardiovascular evaluation and cardiac rhythm assessment using routine 2-minute ECG or good quality ECG tracing during echocardiographic examination. Atrial fibrillation was diagnosed in 59 dogs with a prevalence of 2.7%. Univariate analysis showed that mixed breed, male sex, advanced ACVIM stage, left atrial and ventricular enlargement, fractional shortening (FS), and presence of pulmonary hypertension were significantly associated with development of AF. According to 2 multivariable models, the left atrium (LA)-to-aorta ratio (odds ratio [OR] = 14.011, 7.463-26.304), early trans-mitral velocity (OR = 2.204, 1.192-4.076), body weight (OR = 1.094, 1.058-1.130), and FS (OR = 0.899, 0.865-0.934) and LA (OR = 5.28, 3.377-8.092), advanced ACVIM stage (OR = 4.922, 1.481-16.353), and FS (OR = 0.919, 0.881-0.959) were significant predictors of AF for models 1 and 2, respectively. Atrial fibrillation is an uncommon complication of MMVD and is significantly associated with the more advanced stage of the disease, increased LA dimension and body weight, and decreased FS.

Sections du résumé

BACKGROUND BACKGROUND
Atrial fibrillation (AF) is a common supraventricular arrhythmia more frequently observed in large breed dogs.
OBJECTIVES OBJECTIVE
Estimate the prevalence of AF in dogs with myxomatous mitral valve disease (MMVD) and identify risk factors for developing AF.
ANIMALS METHODS
A total of 2194 client-owned dogs with MMVD, including 1280, 588, 290, and 36 dogs in ACVIM stages B1, B2, C, and D, respectively.
METHODS METHODS
Retrospective, cross-sectional study. The medical databases of 3 veterinary teaching hospitals were reviewed. Inclusion criteria were a diagnosis of MMVD after complete cardiovascular evaluation and cardiac rhythm assessment using routine 2-minute ECG or good quality ECG tracing during echocardiographic examination.
RESULTS RESULTS
Atrial fibrillation was diagnosed in 59 dogs with a prevalence of 2.7%. Univariate analysis showed that mixed breed, male sex, advanced ACVIM stage, left atrial and ventricular enlargement, fractional shortening (FS), and presence of pulmonary hypertension were significantly associated with development of AF. According to 2 multivariable models, the left atrium (LA)-to-aorta ratio (odds ratio [OR] = 14.011, 7.463-26.304), early trans-mitral velocity (OR = 2.204, 1.192-4.076), body weight (OR = 1.094, 1.058-1.130), and FS (OR = 0.899, 0.865-0.934) and LA (OR = 5.28, 3.377-8.092), advanced ACVIM stage (OR = 4.922, 1.481-16.353), and FS (OR = 0.919, 0.881-0.959) were significant predictors of AF for models 1 and 2, respectively.
CONCLUSIONS AND CLINICAL IMPORTANCE CONCLUSIONS
Atrial fibrillation is an uncommon complication of MMVD and is significantly associated with the more advanced stage of the disease, increased LA dimension and body weight, and decreased FS.

Identifiants

DOI: 10.1111/jvim.15927 PMID: 33031593 PMC: PMC7694843
pubmed: 33031593
doi: 10.1111/jvim.15927
pmc: PMC7694843
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2223-2231

Informations de copyright

© 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.

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Auteurs

Carlo Guglielmini (C)

Department of Animal Medicine, Production and Health, University of Padua, Padua, Italy.
ORCID: 0000-0001-7575-3646

Marlos Goncalves Sousa (M)

Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Brazil.

Marco Baron Toaldo (M)

Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
ORCID: 0000-0001-9609-1856

Carlotta Valente (C)

Department of Animal Medicine, Production and Health, University of Padua, Padua, Italy.

Vinicius Bentivoglio (V)

Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Brazil.

Chiara Mazzoldi (C)

Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.

Ilaria Bergamin (I)

Department of Animal Medicine, Production and Health, University of Padua, Padua, Italy.

Michele Drigo (M)

Department of Animal Medicine, Production and Health, University of Padua, Padua, Italy.

Helen Poser (H)

Department of Animal Medicine, Production and Health, University of Padua, Padua, Italy.

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Classifications MeSH

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questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études transversales › Prevalence and risk factors for atrial...
questionsmedicales.fr › Maladies de l'animal › Maladies des chiens › Prevalence and risk factors for atrial...
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