Differences in post-traumatic stress, anxiety and depression following miscarriage or ectopic pregnancy between women and their partners: multicenter prospective cohort study.


Journal

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
ISSN: 1469-0705
Titre abrégé: Ultrasound Obstet Gynecol
Pays: England
ID NLM: 9108340

Informations de publication

Date de publication:
01 2021
Historique:
received: 15 08 2020
revised: 04 10 2020
accepted: 04 10 2020
pubmed: 9 10 2020
medline: 15 12 2021
entrez: 8 10 2020
Statut: ppublish

Résumé

To investigate and compare post-traumatic stress (PTS), depression and anxiety in women and their partners over a 9-month period following miscarriage or ectopic pregnancy. This was a prospective cohort study. Consecutive women and their partners were approached in the early pregnancy units of three hospitals in central London. At 1, 3 and 9 months after early pregnancy loss, recruits were e-mailed links to surveys containing the Hospital Anxiety and Depression Scale and the Post-traumatic Stress Diagnostic Scale. The proportion of participants meeting the screening criteria for moderate or severe anxiety or depression and PTS was assessed. Mixed-effects logistic regression was used to analyze differences between women and their partners and their evolution over time. In total, 386 partners were approached after the woman in whom the early pregnancy loss had been diagnosed consented to participate, and 192 couples were recruited. All partners were male. Response rates were 60%, 48% and 39% for partners and 78%, 70% and 59% for women, at 1, 3 and 9 months, respectively. Of the partners, 7% met the criteria for PTS at 1 month, 8% at 3 months and 4% at 9 months, compared with 34%, 26% and 21% of women, respectively. Partners also experienced lower rates of moderate/severe anxiety (6% vs 30% at 1 month, 9% vs 25% at 3 months and 6% vs 22% at 9 months) and moderate/severe depression (2% vs 10% at 1 month, 5% vs 8% at 3 months and 1% vs 7% at 9 months). The odds ratios for psychological morbidity in partners vs women after 1 month were 0.02 (95% CI, 0.004-0.12) for PTS, 0.05 (95% CI, 0.01-0.19) for moderate/severe anxiety and 0.15 (95% CI, 0.02-0.96) for moderate/severe depression. Morbidity for each outcome decreased modestly over time, without strong evidence of a different evolution between women and their partners. Some partners report clinically relevant levels of PTS, anxiety and depression after pregnancy loss, though to a far lesser extent than women physically experiencing the loss. © 2020 International Society of Ultrasound in Obstetrics and Gynecology.

Identifiants

pubmed: 33032364
doi: 10.1002/uog.23147
doi:

Types de publication

Comparative Study Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

141-148

Subventions

Organisme : Imperial Health Charity
ID : 141517

Informations de copyright

© 2020 International Society of Ultrasound in Obstetrics and Gynecology.

Références

Murphy FA. The experience of early miscarriage from a male perspective. J Clin Nurs 1998; 7: 325-332.
Beutel M, Willner H, Deckardt R, Von Rad M, Weiner H. Similarities and differences in couples' grief reactions following a miscarriage: results from a longitudinal study. J Psychosom Res 1996; 40: 245-253.
Johnson MP, Puddifoot JE. The grief response in the partners of women who miscarry. Br J Med Psychol 1996; 69: 313-327.
Khan RA, Drudy L, Sheehan J, Harrison RF, Geary M. Early pregnancy loss: how do men feel? Ir Med J 2004; 97: 217-218.
Conway K, Russell G. Couples' grief and experience of support in the aftermath of miscarriage. Br J Med Psychol 2000; 73: 531-545.
Cumming GP, Klein S, Bolsover D, Lee AJ, Alexander DA, Maclean M, Jurgens JD. The emotional burden of miscarriage for women and their partners: trajectories of anxiety and depression over 13 months. BJOG 2007; 114: 1138-1145.
Kong GW, Chung TK, Lai BP, Lok IH. Gender comparison of psychological reaction after miscarriage - a 1-year longitudinal study. BJOG 2010; 117: 1211-1219.
Johnson MP, Baker SR. Implications of coping repertoire as predictors of men's stress, anxiety and depression following pregnancy, childbirth and miscarriage: a longitudinal study. J Psychosom Obstet Gynaecol 2004; 25: 87-98.
Farren J, Mitchell-Jones N, Verbakel JY, Timmerman D, Jalmbrant M, Bourne T. The psychological impact of early pregnancy loss. Hum Reprod Update 2018; 24: 731-749.
Farren J, Jalmbrant M, Falconieri N, Mitchell-Jones N, Bobdiwala S, Al-Memar M, Tapp S, Van Calster B, Wynants L, Timmerman D, Bourne T. Posttraumatic stress, anxiety and depression following miscarriage and ectopic pregnancy: a multicenter, prospective, cohort study. Am J Obstet Gynecol 2020; 222: 367.e1-367.e22.
Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the Hospital Anxiety and Depression Scale: An updated literature review. J Psychosom Res 2002; 52: 69-77.
Foa E, Cashman L, Jaycox L, Perry K. The validation of a self-report measure of posttraumatic stress disorder: The Posttraumatic Diagnostic Scale. Psychol Assess 1997; 9: 445-451.
Rosellini AJ, Stein MB, Colpe LJ, Heeringa SG, Petukhova MV, Sampson NA, Schoenbaum M, Ursano RJ, Kessler RC; Army STARRS Collaborators. Approximating a DSM-5 Diagnosis of PTSD Using DSM-IV Criteria. Depress Anxiety 2015; 32: 493-501.
Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983; 67: 361-370.
Ehring T, Kleim B, Clark DM, Foa EB, Ehlers A. Screening for posttraumatic stress disorder: what combination of symptoms predicts best? J Nerv Ment Dis 2007; 195: 1004-1012.
Crawford JR, Henry JD, Crombie C, Taylor EP. Normative data for the HADS from a large non-clinical sample. Br J Clin Psychol 2001; 40: 429-434.
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5). American Psychiatric Association: Washington, DC, USA, 2013.
Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB. Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry 1995; 52: 1048-1060.
Wojnar D, Swanson KM. Why shouldn't lesbian women who miscarry receive special consideration? A viewpoint. J GLBT Family Studies 2006; 2: 1-12.
Gold KJ, Sen A, Hayward RA. Marriage and cohabitation outcomes after pregnancy loss. Pediatrics 2010; 125: e1202-1207.

Auteurs

J Farren (J)

Tommy's National Centre for Miscarriage Research, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, UK.
Department of Obstetrics and Gynaecology, Imperial College Healthcare Trust, London, UK.

M Jalmbrant (M)

Tommy's National Centre for Miscarriage Research, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, UK.

N Falconieri (N)

KU Leuven, Department of Development and Regeneration, Leuven, Belgium.

N Mitchell-Jones (N)

Tommy's National Centre for Miscarriage Research, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, UK.
Department of Obstetrics and Gynaecology, Imperial College Healthcare Trust, London, UK.
Department of Obstetrics and Gynaecology, Chelsea and Westminster NHS Trust, London, UK.

S Bobdiwala (S)

Tommy's National Centre for Miscarriage Research, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, UK.
Department of Obstetrics and Gynaecology, Imperial College Healthcare Trust, London, UK.

M Al-Memar (M)

Tommy's National Centre for Miscarriage Research, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, UK.
Department of Obstetrics and Gynaecology, Imperial College Healthcare Trust, London, UK.

S Tapp (S)

Department of Obstetrics and Gynaecology, Imperial College Healthcare Trust, London, UK.

B Van Calster (B)

KU Leuven, Department of Development and Regeneration, Leuven, Belgium.
Department of Biomedical Data Sciences, Leiden University Medical Centre (LUMC), Leiden, The Netherlands.
EPI-centre, KU Leuven, Leuven, Belgium.

L Wynants (L)

KU Leuven, Department of Development and Regeneration, Leuven, Belgium.
EPI-centre, KU Leuven, Leuven, Belgium.
Department of Epidemiology, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.

D Timmerman (D)

KU Leuven, Department of Development and Regeneration, Leuven, Belgium.
Department of Obstetrics and Gynaecology, University Hospitals Leuven, Leuven, Belgium.

T Bourne (T)

Tommy's National Centre for Miscarriage Research, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, UK.
Department of Obstetrics and Gynaecology, Imperial College Healthcare Trust, London, UK.
KU Leuven, Department of Development and Regeneration, Leuven, Belgium.

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