Mass acquisition of human periodontal ligament stem cells.
Induced pluripotent stem cells
Mesoderm specific transcript
Periodontal ligament stem cells
Periodontal tissue
Regenerative medicine
Semaphorin 3A
Journal
World journal of stem cells
ISSN: 1948-0210
Titre abrégé: World J Stem Cells
Pays: United States
ID NLM: 101535826
Informations de publication
Date de publication:
26 Sep 2020
26 Sep 2020
Historique:
received:
19
05
2020
revised:
08
06
2020
accepted:
01
08
2020
entrez:
9
10
2020
pubmed:
10
10
2020
medline:
10
10
2020
Statut:
ppublish
Résumé
The periodontal ligament (PDL) is an essential fibrous tissue for tooth retention in the alveolar bone socket. PDL tissue further functions to cushion occlusal force, maintain alveolar bone height, allow orthodontic tooth movement, and connect tooth roots with bone. Severe periodontitis, deep caries, and trauma cause irreversible damage to this tissue, eventually leading to tooth loss through the destruction of tooth retention. Many patients suffer from these diseases worldwide, and its prevalence increases with age. To address this issue, regenerative medicine for damaged PDL tissue as well as the surrounding tissues has been extensively investigated regarding the potential and effectiveness of stem cells, scaffolds, and cytokines as well as their combined applications. In particular, PDL stem cells (PDLSCs) have been well studied. In this review, I discuss comprehensive studies on PDLSCs performed
Identifiants
pubmed: 33033562
doi: 10.4252/wjsc.v12.i9.1023
pmc: PMC7524700
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1023-1031Informations de copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: There is no conflict of interest.
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