Differentiation of inflammatory papulosquamous skin diseases based on skin biophysical and ultrasonographic properties: A decision tree model.
Biophysical properties
decision tree
differential diagnosis
inflammatory papulosquamous diseases
ultrasonographic findings
Journal
Indian journal of dermatology, venereology and leprology
ISSN: 0973-3922
Titre abrégé: Indian J Dermatol Venereol Leprol
Pays: United States
ID NLM: 7701852
Informations de publication
Date de publication:
Historique:
pubmed:
11
10
2020
medline:
18
9
2021
entrez:
10
10
2020
Statut:
ppublish
Résumé
The biophysical and ultrasonographic properties of the skin change in papulosquamous diseases. : To identify biophysical and ultrasonographic properties for the differentiation of five main groups of papulosquamous skin diseases. Fifteen biophysical and ultrasonographic parameters were measured by multiprobe adapter system and high-frequency ultrasonography in active lesions and normal control skin in patients with chronic eczema, psoriasis, lichen planus, pityriasis rosea and parapsoriasis/mycosis fungoides. Using histological diagnosis as a gold standard, a decision tree analysis was performed based on the mean percentage changes of these parameters [(lesion-control/control) ×100] for differentiation of the diseases. The accuracy of the decision tree model for differentiation of five diseases was 67% which developed based on changes in stratum corneum hydration, epidermal thickness, skin pH, melanin index, R0 (reciprocal of firmness) and erythema. Among the flowcharts for pairs of diseases, three models for differentiation had high accuracy (> 95%): those of psoriasis from lichen planus, pityriasis rosea, and parapsoriasis/mycosis fungoides. Validation studies on a larger sample size in situations where the diagnosis is unclear are needed to confirm the accuracy and applicability of decision trees. Skin biophysical and ultrasonographic properties may help in the differentiation of papulosquamous diseases as simple and non-invasive tools.
Sections du résumé
BACKGROUND
BACKGROUND
The biophysical and ultrasonographic properties of the skin change in papulosquamous diseases.
AIMS
OBJECTIVE
: To identify biophysical and ultrasonographic properties for the differentiation of five main groups of papulosquamous skin diseases.
METHODS
METHODS
Fifteen biophysical and ultrasonographic parameters were measured by multiprobe adapter system and high-frequency ultrasonography in active lesions and normal control skin in patients with chronic eczema, psoriasis, lichen planus, pityriasis rosea and parapsoriasis/mycosis fungoides. Using histological diagnosis as a gold standard, a decision tree analysis was performed based on the mean percentage changes of these parameters [(lesion-control/control) ×100] for differentiation of the diseases.
RESULTS
RESULTS
The accuracy of the decision tree model for differentiation of five diseases was 67% which developed based on changes in stratum corneum hydration, epidermal thickness, skin pH, melanin index, R0 (reciprocal of firmness) and erythema. Among the flowcharts for pairs of diseases, three models for differentiation had high accuracy (> 95%): those of psoriasis from lichen planus, pityriasis rosea, and parapsoriasis/mycosis fungoides.
LIMITATIONS
CONCLUSIONS
Validation studies on a larger sample size in situations where the diagnosis is unclear are needed to confirm the accuracy and applicability of decision trees.
CONCLUSION
CONCLUSIONS
Skin biophysical and ultrasonographic properties may help in the differentiation of papulosquamous diseases as simple and non-invasive tools.
Identifiants
pubmed: 33037158
pii: 297342
doi: 10.4103/ijdvl.IJDVL_842_19
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
752Déclaration de conflit d'intérêts
None