High-fluence light emitting diode-red light inhibits cell cycle progression in human dermal fibroblasts.
fibroblast
light emitting diode
photobiomodulation
red light
skin fibrosis
Journal
Journal of biophotonics
ISSN: 1864-0648
Titre abrégé: J Biophotonics
Pays: Germany
ID NLM: 101318567
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
07
09
2020
revised:
02
10
2020
accepted:
04
10
2020
pubmed:
11
10
2020
medline:
13
7
2021
entrez:
10
10
2020
Statut:
ppublish
Résumé
Skin fibrosis is a debilitating feature of several systemic and dermatologic diseases. While current treatment options carry significant risk of side effects and recurrence, high-fluence light emitting diode-generated red light (LED-RL) is an alternative therapeutic that is safe, non-invasive, and accessible. We previously demonstrated LED-RL decreases fibroblast proliferation, a key pathogenic component of fibrosis. However, the cellular mechanism by which high fluence LED-RL modulates fibroblast proliferation is unclear. Herein, we explored the effects of high fluence LED-RL on human dermal fibroblast cell cycle progression. We demonstrate that LED-RL at 640 J/cm
Identifiants
pubmed: 33038043
doi: 10.1002/jbio.202000359
pmc: PMC8935855
mid: NIHMS1781279
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202000359Subventions
Organisme : NIGMS NIH HHS
ID : K23 GM117309
Pays : United States
Organisme : NIGMS NIH HHS
ID : K23GM117309
Pays : United States
Informations de copyright
© 2020 The Authors. Journal of Biophotonics published by Wiley-VCH GmbH.
Références
J Cosmet Laser Ther. 2005 Dec;7(3-4):177-89
pubmed: 16414906
Expert Rev Mol Med. 2002 Dec 02;4(26):1-22
pubmed: 14585163
Sci Rep. 2019 Aug 19;9(1):12059
pubmed: 31427681
BMJ. 2003 Jan 11;326(7380):88-92
pubmed: 12521975
Nat Rev Mol Cell Biol. 2019 Apr;20(4):199-210
pubmed: 30824861
Annu Rev Biochem. 2016 Jun 2;85:375-404
pubmed: 27145840
Cold Spring Harb Perspect Biol. 2010 Aug;2(8):a000935
pubmed: 20679336
Matrix Biol. 2016 Apr;51:37-46
pubmed: 26844756
PLoS One. 2012;7(4):e28203
pubmed: 22529890
J Cell Mol Med. 2019 May;23(5):3563-3571
pubmed: 30873733
J Dtsch Dermatol Ges. 2016 May;14(5):467-78
pubmed: 27119466
Cell Cycle. 2013 Aug 1;12(15):2468-78
pubmed: 23839036
J Invest Dermatol. 2012 Jul;132(7):1901-7
pubmed: 22318388
Life Sci. 2019 Jul 15;229:200-209
pubmed: 31047894
Nat Med. 2012 Jul 06;18(7):1028-40
pubmed: 22772564
Cold Spring Harb Perspect Biol. 2010 Jan;2(1):a001008
pubmed: 20182602
Curr Dermatol Rep. 2016;5:121-128
pubmed: 27182462
J Biophotonics. 2016 Dec;9(11-12):1167-1179
pubmed: 27174640
Wound Repair Regen. 2016 Mar;24(2):215-22
pubmed: 26704519
Nat Med. 2010 May;16(5):535-43, 1p following 143
pubmed: 20436483
Dermatol Surg. 2018 Oct;44(10):1317-1322
pubmed: 29846344
J Am Acad Dermatol. 2017 May;76(5):958-972.e2
pubmed: 28259441
Dermatol Surg. 2017 Jan;43(1):81-86
pubmed: 28027199
Trials. 2019 Jul 15;20(1):432
pubmed: 31307501
Nat Rev Cancer. 2014 May;14(5):359-70
pubmed: 24739573