Hybrid Coronary Revascularization Versus Conventional Coronary Artery Bypass Surgery: Utilization and Comparative Outcomes.


Journal

Circulation. Cardiovascular interventions
ISSN: 1941-7632
Titre abrégé: Circ Cardiovasc Interv
Pays: United States
ID NLM: 101499602

Informations de publication

Date de publication:
10 2020
Historique:
pubmed: 13 10 2020
medline: 22 6 2021
entrez: 12 10 2020
Statut: ppublish

Résumé

Hybrid coronary revascularization (HCR) treats multivessel coronary artery disease by combining a minimally invasive surgical approach to the left anterior descending artery with percutaneous coronary intervention for non-left anterior descending diseased coronary arteries. The objective of this study is to compare HCR and conventional coronary artery bypass graft (CABG) surgery medium-term outcomes. Data from multivessel disease patients in New York's cardiac surgery and percutaneous coronary intervention registries in 2010 to 2016 were used to compare mortality and repeat revascularization rates for HCR and conventional CABG after using propensity matching to reduce selection bias. There was a total of 303 HCR (0.80%) patients and 37 556 conventional CABG patients after exclusions. After propensity matching, the respective median follow-up times were 3.72 years and 3.76 years. There was no difference between HCR and conventional CABG in survival at 6 years (80.9% versus 85.8%%, adjusted hazard ratio, 1.44 [0.90-2.31]), but HCR had higher mortality excluding deaths during the first year (adjusted hazard ratio, 1.88 [1.10-3.23]). Conventional CABG patients were more likely to be free from repeat revascularization at 6 years than HCR patients (88.2% versus 76.6%; hazard ratio, 2.22 [1.44-3.42]). HCR is rarely performed for patients with multivessel coronary artery disease. HCR and conventional CABG had no different 6-year mortality rates, but HCR had higher mortality after 1 year and higher rates of subsequent revascularization that were caused by both the need for repeat revascularization in the left anterior descending artery where minimally invasive CABG was performed, and in the coronary arteries where percutaneous coronary intervention was performed. Graphic Abstract: A graphic abstract is available for this article.

Sections du résumé

BACKGROUND
Hybrid coronary revascularization (HCR) treats multivessel coronary artery disease by combining a minimally invasive surgical approach to the left anterior descending artery with percutaneous coronary intervention for non-left anterior descending diseased coronary arteries. The objective of this study is to compare HCR and conventional coronary artery bypass graft (CABG) surgery medium-term outcomes.
METHODS
Data from multivessel disease patients in New York's cardiac surgery and percutaneous coronary intervention registries in 2010 to 2016 were used to compare mortality and repeat revascularization rates for HCR and conventional CABG after using propensity matching to reduce selection bias.
RESULTS
There was a total of 303 HCR (0.80%) patients and 37 556 conventional CABG patients after exclusions. After propensity matching, the respective median follow-up times were 3.72 years and 3.76 years. There was no difference between HCR and conventional CABG in survival at 6 years (80.9% versus 85.8%%, adjusted hazard ratio, 1.44 [0.90-2.31]), but HCR had higher mortality excluding deaths during the first year (adjusted hazard ratio, 1.88 [1.10-3.23]). Conventional CABG patients were more likely to be free from repeat revascularization at 6 years than HCR patients (88.2% versus 76.6%; hazard ratio, 2.22 [1.44-3.42]).
CONCLUSIONS
HCR is rarely performed for patients with multivessel coronary artery disease. HCR and conventional CABG had no different 6-year mortality rates, but HCR had higher mortality after 1 year and higher rates of subsequent revascularization that were caused by both the need for repeat revascularization in the left anterior descending artery where minimally invasive CABG was performed, and in the coronary arteries where percutaneous coronary intervention was performed. Graphic Abstract: A graphic abstract is available for this article.

Identifiants

pubmed: 33040581
doi: 10.1161/CIRCINTERVENTIONS.120.009386
doi:

Types de publication

Comparative Study Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

e009386

Auteurs

Edward L Hannan (EL)

School of Public Health, University at Albany, State University of New York, NY (E.L.H., Y.W., K.C.).

Yifeng Wu (Y)

School of Public Health, University at Albany, State University of New York, NY (E.L.H., Y.W., K.C.).

Kimberly Cozzens (K)

School of Public Health, University at Albany, State University of New York, NY (E.L.H., Y.W., K.C.).

Thoralf M Sundt (TM)

Cardiac Surgical Division, Massachusetts General Hospital, Boston (T.M.S.).

Leonard Girardi (L)

Department of Cardiothoracic Surgery, Weill Cornell Medical Center, NY (L.G.).

Joanna Chikwe (J)

Department of Cardiac Surgery, Cedars-Sinai Medical Center, Los Angeles, CA (J.C.).

Andrew Wechsler (A)

Department of Cardiothoracic Surgery, Drexel University, Philadelphia, PA (A.W.).

Craig R Smith (CR)

Department of Surgery, Columbia-Presbyterian Medical Center, NY (C.R.S.).

Jeffrey P Gold (JP)

Chancellor, University of Nebraska Medical Center, Omaha, NE (J.P.G.).

Stephen J Lahey (SJ)

Division of Cardiothoracic Surgery, University of Connecticut, Storrs (S.J.L.).

Desmond Jordan (D)

Department of Anesthesiology, Columbia-Presbyterian Medical Center, NY (D.J.).

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