Near-infrared fluorescence imaging compared to standard sentinel lymph node detection with blue dye in patients with vulvar cancer - a randomized controlled trial.
Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell
/ diagnosis
Coloring Agents
/ administration & dosage
Female
Humans
Intraoperative Care
/ methods
Lymph Node Excision
Lymphatic Metastasis
/ diagnosis
Middle Aged
Netherlands
Operative Time
Optical Imaging
/ methods
Radiopharmaceuticals
/ administration & dosage
Sentinel Lymph Node
/ diagnostic imaging
Sentinel Lymph Node Biopsy
/ methods
Time Factors
Vulvar Neoplasms
/ pathology
Vulvectomy
ICG-(99m)Tc-nanocolloid
Indocyanine green
Near-infrared fluorescence imaging
Randomized controlled trial
Sentinel lymph node
Vulvar cancer
Journal
Gynecologic oncology
ISSN: 1095-6859
Titre abrégé: Gynecol Oncol
Pays: United States
ID NLM: 0365304
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
04
08
2020
accepted:
27
09
2020
pubmed:
13
10
2020
medline:
17
4
2021
entrez:
12
10
2020
Statut:
ppublish
Résumé
The aim of this study was to assess the superiority of ICG- In this multicenter, randomized controlled trial, VSCC patients underwent either the standard SLN procedure or with the hybrid tracer ICG- Forty-eight patients were randomized to the standard (n = 24) or fluorescence imaging group (n = 24) using ICG- Intraoperative visual detection of SLNs in patients with VSCC using ICG- Netherlands Trial Register (Trial ID NL7443).
Identifiants
pubmed: 33041071
pii: S0090-8258(20)33954-8
doi: 10.1016/j.ygyno.2020.09.044
pii:
doi:
Substances chimiques
Coloring Agents
0
Radiopharmaceuticals
0
Types de publication
Comparative Study
Equivalence Trial
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
672-680Subventions
Organisme : European Research Council
ID : 323105
Pays : International
Informations de copyright
Copyright © 2020 The Author(s). Published by Elsevier Inc. All rights reserved.