Association of schistosomiasis and risk of prostate cancer development in residents of Murehwa rural community, Zimbabwe.

Male genital schistosomiasis Prostate cancer Prostate specific antigen S. haematobium S. mansoni Schistosomiasis Urogenital schistosomiasis

Journal

Infectious agents and cancer
ISSN: 1750-9378
Titre abrégé: Infect Agent Cancer
Pays: England
ID NLM: 101276559

Informations de publication

Date de publication:
2020
Historique:
received: 15 07 2020
accepted: 23 09 2020
entrez: 12 10 2020
pubmed: 13 10 2020
medline: 13 10 2020
Statut: epublish

Résumé

Prostatic male genital schistosomiasis and prostate cancer co-existence cases are uncommon however, some studies have indicated that schistosomiasis may trigger development of prostate cancer regardless of age. Schistosomiasis is a public health problem in sub-Saharan Africa and may account for some undocumented cases of schistosomiasis prostatic cancer in schistosome endemic rural communities. It is against this background that we investigated the association between schistosomiasis and risk of prostate cancer development in residents of Murehwa Community, a schistosomiasis endemic area. We conducted a cross sectional study involving 366 men residing in Murehwa District, Zimbabwe. Prevalence of Urogenital schistosome infections and history of schistosome infections were associated with prostate specific antigen levels, an indicator for risk of prostate cancer. Therefore,

Sections du résumé

BACKGROUND BACKGROUND
Prostatic male genital schistosomiasis and prostate cancer co-existence cases are uncommon however, some studies have indicated that schistosomiasis may trigger development of prostate cancer regardless of age. Schistosomiasis is a public health problem in sub-Saharan Africa and may account for some undocumented cases of schistosomiasis prostatic cancer in schistosome endemic rural communities. It is against this background that we investigated the association between schistosomiasis and risk of prostate cancer development in residents of Murehwa Community, a schistosomiasis endemic area.
METHODOLOGY METHODS
We conducted a cross sectional study involving 366 men residing in Murehwa District, Zimbabwe.
RESULTS RESULTS
Prevalence of
CONCLUSION CONCLUSIONS
Urogenital schistosome infections and history of schistosome infections were associated with prostate specific antigen levels, an indicator for risk of prostate cancer. Therefore,

Identifiants

pubmed: 33042215
doi: 10.1186/s13027-020-00327-2
pii: 327
pmc: PMC7541262
doi:

Types de publication

Journal Article

Langues

eng

Pagination

59

Informations de copyright

© The Author(s) 2020.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare that they have no competing interests.

Références

Braz J Infect Dis. 2002 Feb;6(1):45-9
pubmed: 11980603
J Surg Case Rep. 2020 Jun 01;2020(5):rjaa144
pubmed: 32509270
Neoplasma. 1985;32(5):613-22
pubmed: 2415839
Urology. 1992 Jun;39(6):547-9
pubmed: 1615606
Pathology. 1995 Apr;27(2):115-6
pubmed: 7567134
Int J Public Health. 2015 Nov;60(7):839-48
pubmed: 26298443
Parasite Immunol. 2014 Aug;36(8):347-57
pubmed: 25142505
Tropenmed Parasitol. 1982 Dec;33(4):227-8
pubmed: 7164164
Am J Trop Med Hyg. 1970 Sep;19(5):779-84
pubmed: 5453906
Histopathology. 1995 Aug;27(2):187-9
pubmed: 8835268
CA Cancer J Clin. 2010 Mar-Apr;60(2):70-98
pubmed: 20200110
PLoS Negl Trop Dis. 2014 Aug 14;8(8):e3014
pubmed: 25121489
Braz J Infect Dis. 2015 Mar-Apr;19(2):196-205
pubmed: 25636189
Anal Quant Cytopathol Histpathol. 2013 Jun;35(3):178-80
pubmed: 24344506
Trop Med Int Health. 1999 Dec;4(12):791-3
pubmed: 10632985
Parasitol Res. 2015 Feb;114(2):351-8
pubmed: 25544700
Rev Urol. 2003;5 Suppl 6:S3-9
pubmed: 16985974
N Engl J Med. 2004 May 27;350(22):2239-46
pubmed: 15163773
Ann Intern Med. 2002 Dec 3;137(11):915-6
pubmed: 12458992
Ann Intern Med. 2017 Oct 3;167(7):509-510
pubmed: 28869975
J Urol. 1995 Aug;154(2 Pt 1):407-13
pubmed: 7541857
Rev Soc Bras Med Trop. 2006 Mar-Apr;39(2):233-4
pubmed: 16699658
J Urol. 1991 May;145(5):907-23
pubmed: 1707989
Urology. 2001 Sep;58(3):411-6
pubmed: 11549490
J Urol. 1998 Dec;160(6 Pt 2):2381-92
pubmed: 9817389
Cochrane Database Syst Rev. 2013 Jan 31;(1):CD004720
pubmed: 23440794
J Helminthol. 2001 Sep;75(3):223-5
pubmed: 11551310
JAMA. 1995 Jan 25;273(4):289-94
pubmed: 7529341
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Prostate. 2019 Aug;79(11):1316-1325
pubmed: 31212384
Int J STD AIDS. 2014 Sep;25(10):705-15
pubmed: 24621458
PLoS Negl Trop Dis. 2011 Dec;5(12):e1396
pubmed: 22163056
Acta Med Indones. 2016 Jul;48(3):228-238
pubmed: 27840359
Int J Cancer. 2013 Aug 1;133(3):721-9
pubmed: 23364833
N Engl J Med. 1991 Apr 25;324(17):1156-61
pubmed: 1707140

Auteurs

Emilia T Choto (ET)

University of KwaZulu Natal, School of Nursing and Public Health, 6 College of Health Sciences, Howard College, 269 Mazisi Kunene Road, Berea, Durban, 4041,7 South Africa.

Takafira Mduluza (T)

University of Zimbabwe, Biochemistry Department, P.O. Box MP 167, Mount Pleasant, Harare, Zimbabwe.
University of KwaZulu Natal, School of Laboratory Medicine and Medical Sciences, Howard College, 269 Mazisi Kunene Road, Berea, Durban, 4041 South Africa.

Francisca Mutapi (F)

Centre for Infection, Immunity and Evolution, Institute of Immunology and Infection Research, University of Edinburgh, Ashworth Laboratories, King's Buildings, Charlotte Auerbach Road, Edinburgh, EH9 3FL UK.

Moses J Chimbari (MJ)

University of KwaZulu Natal, School of Nursing and Public Health, 6 College of Health Sciences, Howard College, 269 Mazisi Kunene Road, Berea, Durban, 4041,7 South Africa.

Classifications MeSH