Siblings with Acquired Tracheocele: Possible Hereditary Etiopathogenesis?


Journal

Head and neck pathology
ISSN: 1936-0568
Titre abrégé: Head Neck Pathol
Pays: United States
ID NLM: 101304010

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 23 09 2019
accepted: 07 10 2020
pubmed: 13 10 2020
medline: 18 1 2022
entrez: 12 10 2020
Statut: ppublish

Résumé

Tracheocele is a herniation of the tracheal mucosa through a defect in the tracheal wall. Familiar and/or genetical factors have never been taken into consideration in the etiopathogenesis of acquired tracheocele. Acquired tracheocele occurred in a brother and a sister from India. CT scan of the neck showed an air cyst next to the right tracheal wall. They underwent surgical excision through a transverse cervical incision. Histopathology of the lesion revealed a fibrous sac lined by a pseudostratified columnar respiratory epithelium in both patients. They had no recurrence of tracheocele at 12 months follow up. Genetic counseling did not evidence any significative associated abnormalities. No previous cases of familiar acquired tracheocele have been reported in the literature. Given the rarity of the lesion occurring in more than one member of a family, hereditary factors could be supposed as contributing factors in the etiopathogenesis of acquired tracheocele.

Identifiants

pubmed: 33044722
doi: 10.1007/s12105-020-01235-y
pii: 10.1007/s12105-020-01235-y
pmc: PMC8385091
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

999-1003

Informations de copyright

© 2020. Springer Science+Business Media, LLC, part of Springer Nature.

Références

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pubmed: 23430435

Auteurs

Cecilia Botti (C)

Department of Otolaryngology Head Neck Surgery, University Hospital of Modena, Via Largo del Pozzo, 41125, Modena, Italy.
Clinical and Experimental Medicine, University of Modena and Reggio Emilia, Modena, Italy.

Francesco Maccarrone (F)

Department of Otolaryngology Head Neck Surgery, University Hospital of Modena, Via Largo del Pozzo, 41125, Modena, Italy. fra.maccarrone@gmail.com.

Giuditta Bernardelli (G)

Department of Pathology, University Hospital of Modena, Modena, Italy.

Massimo Lupi (M)

Department of Pathology, University Hospital of Modena, Modena, Italy.

Livio Presutti (L)

Department of Otolaryngology Head Neck Surgery, University Hospital of Modena, Via Largo del Pozzo, 41125, Modena, Italy.

Francesco Mattioli (F)

Department of Otolaryngology Head Neck Surgery, University Hospital of Modena, Via Largo del Pozzo, 41125, Modena, Italy.

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Classifications MeSH