Protective effects of new femoral reaming techniques (Reamer irrigator aspirator, RIA I and II) on pulmonary function and posttraumatic contusion (CT morphology) - results from a standardized large animal model.


Journal

Injury
ISSN: 1879-0267
Titre abrégé: Injury
Pays: Netherlands
ID NLM: 0226040

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 01 08 2020
revised: 01 10 2020
accepted: 05 10 2020
pubmed: 14 10 2020
medline: 22 6 2021
entrez: 13 10 2020
Statut: ppublish

Résumé

The effects of reaming for preparation of intramedullary fixation in long bone fractures have been widely studied. We compared pulmonary and systemic effects between conventional reaming with reamer irrigator aspirator and unreamed nailing in an acute porcine trauma model with a standardized femur fracture. In a standardized porcine model, (moderate blunt chest trauma, abdominal injury and femoral shaft fracture), the femur was submitted to intramedullary nailing after resuscitation and normalization of pulmonary function. The treatment groups included 3 reamer types (Group RFN: conventional reaming with Synream; group RIA1; reamer irrigator aspirator, version 2005; group RIA 2; reamer irrigator aspirator, version 2019) and were compared to unreamed femoral nailing (Group UFN). Pulmonary function measurements included arterial partial carbon-dioxide pressure (paCO This study included 24 male animals, mean weight 50.76 ± 4.1 kg n = 6 per group). Group RFN developed a significantly higher partial CO Both RIA 1 and RIA 2 protect the lung from reaming induced dysfunction and have no systemic inflammatory effects, while the negative effects were more sustained after reamed or unreamed nailing. Both RIA 1 and RIA II appear to be of value in terms of a Safe Definitive Surgery (SDS) strategy.

Identifiants

pubmed: 33046248
pii: S0020-1383(20)30827-5
doi: 10.1016/j.injury.2020.10.027
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

26-31

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest No conflicts of interest

Auteurs

Sascha Halvachizadeh (S)

University Hospital Zurich, Department of Trauma, Raemistrasse 100, 8091 Zurich, Switzerland; University of Zurich, University Hospital Zurich, Department of Surgical Research, Harald Tscherne Laboratory for Orthopaedic and Trauma research, Sternwartstrasse 14, 8091 Zurich, Switzerland. Electronic address: sascha.halvachizadeh@usz.ch.

Michel Teuben (M)

University Hospital Zurich, Department of Trauma, Raemistrasse 100, 8091 Zurich, Switzerland; University of Zurich, University Hospital Zurich, Department of Surgical Research, Harald Tscherne Laboratory for Orthopaedic and Trauma research, Sternwartstrasse 14, 8091 Zurich, Switzerland. Electronic address: michel.teuben@usz.ch.

Max Lempert (M)

University Hospital Zurich, Department of Trauma, Raemistrasse 100, 8091 Zurich, Switzerland. Electronic address: maximilian.lempert@usz.ch.

Yannik Kalbas (Y)

University Hospital Zurich, Department of Trauma, Raemistrasse 100, 8091 Zurich, Switzerland. Electronic address: yannik.kalbas@usz.ch.

Nikola Cesarovic (N)

University of Zurich, University Hospital Zurich, Department of Surgical Research, Harald Tscherne Laboratory for Orthopaedic and Trauma research, Sternwartstrasse 14, 8091 Zurich, Switzerland. Electronic address: nikola.cesarovic@hest.ethz.ch.

Miriam Lipiski (M)

University of Zurich, University Hospital Zurich, Department of Surgical Research, Harald Tscherne Laboratory for Orthopaedic and Trauma research, Sternwartstrasse 14, 8091 Zurich, Switzerland. Electronic address: miriam.lipiski@usz.ch.

Emanuel Benninger (E)

Cantonal hospital Winterthur, Department of Orthopaedics and Trauma, Brauerstrasse 15, 8400 Winterthur, Switzerland. Electronic address: emanuel.benninger@ksw.ch.

Paolo Cinelli (P)

University of Zurich, University Hospital Zurich, Department of Surgical Research, Harald Tscherne Laboratory for Orthopaedic and Trauma research, Sternwartstrasse 14, 8091 Zurich, Switzerland. Electronic address: paolo.cinelli@usz.ch.

Roman Pfeifer (R)

University Hospital Zurich, Department of Trauma, Raemistrasse 100, 8091 Zurich, Switzerland; University of Zurich, University Hospital Zurich, Department of Surgical Research, Harald Tscherne Laboratory for Orthopaedic and Trauma research, Sternwartstrasse 14, 8091 Zurich, Switzerland. Electronic address: roman.pfeifer@usz.ch.

Hans-Christoph Pape (HC)

University Hospital Zurich, Department of Trauma, Raemistrasse 100, 8091 Zurich, Switzerland; University of Zurich, University Hospital Zurich, Department of Surgical Research, Harald Tscherne Laboratory for Orthopaedic and Trauma research, Sternwartstrasse 14, 8091 Zurich, Switzerland. Electronic address: hans-christoph.pape@usz.ch.

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Classifications MeSH