Combination treatment algorithm for pigmentary disorders of the face: A prospective observational study in Asian patients.
Carbon dioxide laser
Hydroquinone
Pigmentary disorders
Q-switched alexandrite laser
Retinoic acid
Journal
Journal of plastic, reconstructive & aesthetic surgery : JPRAS
ISSN: 1878-0539
Titre abrégé: J Plast Reconstr Aesthet Surg
Pays: Netherlands
ID NLM: 101264239
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
07
09
2019
revised:
28
02
2020
accepted:
18
08
2020
pubmed:
14
10
2020
medline:
24
2
2021
entrez:
13
10
2020
Statut:
ppublish
Résumé
Most patients with facial pigmentary disorders have multiple disorders. However, there is no definitive treatment algorithm improving various pigmentary disorders simultaneously. To investigate the clinical efficacy and safety of the combination of the Q-switched alexandrite and the carbon dioxide lasers with ZO SKIN HEALTH This prospective observational study enrolled 251 patients with at least one facial pigmentary disorder. We assessed treatment efficacy and investigated which disorders were most responsive to combination treatment and the relationship between doctors' skills, outcomes, and dropout rates. There were 246 patients with lentigo senilis, 186 with moles, 79 with melasma, 53 with seborrheic keratosis, 17 with acquired dermal melanocytosis (ADM), and 16 with freckles. Overall, 227 patients completed treatment. Post-treatment outcomes were excellent in 97, good in 113, fair in 17, and poor in 0 patients. Freckles were the most responsive, and ADM was the least responsive. Patient withdrawal and treatment outcomes did not differ significantly based on the doctors' skills. Overall, 3.2% of patients had adverse events. Our combination algorithm improved several pigmentary disorders of the face simultaneously, regardless of the doctors' proficiency level.
Sections du résumé
BACKGROUND
Most patients with facial pigmentary disorders have multiple disorders. However, there is no definitive treatment algorithm improving various pigmentary disorders simultaneously.
OBJECTIVES
To investigate the clinical efficacy and safety of the combination of the Q-switched alexandrite and the carbon dioxide lasers with ZO SKIN HEALTH
PATIENTS/METHODS
This prospective observational study enrolled 251 patients with at least one facial pigmentary disorder. We assessed treatment efficacy and investigated which disorders were most responsive to combination treatment and the relationship between doctors' skills, outcomes, and dropout rates.
RESULTS
There were 246 patients with lentigo senilis, 186 with moles, 79 with melasma, 53 with seborrheic keratosis, 17 with acquired dermal melanocytosis (ADM), and 16 with freckles. Overall, 227 patients completed treatment. Post-treatment outcomes were excellent in 97, good in 113, fair in 17, and poor in 0 patients. Freckles were the most responsive, and ADM was the least responsive. Patient withdrawal and treatment outcomes did not differ significantly based on the doctors' skills. Overall, 3.2% of patients had adverse events.
CONCLUSIONS
Our combination algorithm improved several pigmentary disorders of the face simultaneously, regardless of the doctors' proficiency level.
Identifiants
pubmed: 33046430
pii: S1748-6815(20)30447-2
doi: 10.1016/j.bjps.2020.08.131
pii:
doi:
Types de publication
Case Reports
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
370-376Informations de copyright
Copyright © 2020. Published by Elsevier Ltd.