Novel Nanocomposites Based on Bacterial Polyester/LDH-SDS Clay for Stem Cells Delivery in Modern Wound Healing Management.
LDH-SDS
melt processing
nanocomposite
polyhydroxyalkanoates
tissue engineering
Journal
Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929
Informations de publication
Date de publication:
10 Oct 2020
10 Oct 2020
Historique:
received:
21
08
2020
revised:
24
09
2020
accepted:
04
10
2020
entrez:
14
10
2020
pubmed:
15
10
2020
medline:
15
10
2020
Statut:
epublish
Résumé
Nanocomposite materials based on poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBHV) and modified mineral clay layered double hydroxides (LDH-SDS) were explored as novel nanostructured materials for potential tissue engineering applications. The mineral clay inorganic phase was modified with an anionic long-chain structure of carbon atoms, such as sodium dodecyl sulfate, in order to increase the compatibility between the two phases. The melt intercalation method used for nanocomposite fabrication ensures a good dispersion of the modified LDH-SDS within the polymer matrix without using a toxic solvent (chloroform). The nanocomposites were found to have an intercalated/exfoliated structure with an enhanced Young modulus and increased stiffness. This could allow them to be considered for autologous stem cells dressings in the view of efficient wound healing applications.
Identifiants
pubmed: 33050441
pii: ma13204488
doi: 10.3390/ma13204488
pmc: PMC7601887
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
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