Clinical characteristics of familial schizophrenia.

Hospitalization Humans Psychotic Disorders / epidemiology Risk Factors Schizophrenia / epidemiology
familial history risk schizophrenia sporadic symptom

Journal

Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists
ISSN: 1758-5872
Titre abrégé: Asia Pac Psychiatry
Pays: Australia
ID NLM: 101506757

Informations de publication

Date de publication:
Jun 2021
Historique:
received: 06 02 2020
accepted: 15 06 2020
pubmed: 15 10 2020
medline: 26 10 2021
entrez: 14 10 2020
Statut: ppublish

Résumé

A family history of psychiatric disorders is one of the strongest risk factors for schizophrenia. The characteristics of patients with a family history of psychiatric disorders have not been systematically evaluated. This multicenter study (26 centers, 2425 cases) was performed in a Chinese population to examine the sociodemographic and clinical characteristics of schizophrenia patients with a family history of psychotic disorders in comparison with those of patients with sporadic schizophrenia. Nineteen percent of patients had a family history of mental disease. Multiple logistic regression analysis revealed that ≥4 hospitalizations (OR = 1.78, P = .004), tobacco dependence (OR = 1.48, P = .006), alcohol dependence (OR = 1.74, P = .013), and physical illness (OR = 1.89, P = .001) were independently and significantly associated with a family history of mental disease. Patients with a family history of mental disorders present different demographics and clinical features than patients without a family history of psychiatric disorders.

Identifiants

DOI: 10.1111/appy.12422 PMID: 33053613
pubmed: 33053613
doi: 10.1111/appy.12422
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

e12422

Subventions

Organisme : Priority of Shanghai key discipline of medicine
ID : 2017ZZ02020
Organisme : Ministry of Science and Technology of China
ID : 2016YFC1306805
Organisme : National Natural Science Foundation of China
ID : 81471359
Organisme : Shanghai Science and technology committee
ID : 14411963400

Informations de copyright

© 2020 John Wiley & Sons Australia, Ltd.

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Auteurs

Na Liu (N)

Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Department of Psychiatry, Shanghai Tongji Hospital of Tongji University, Shanghai, China.

Hui Zhou (H)

Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Xiangyu Xiong (X)

Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Qingwei Li (Q)

Department of Psychiatry, Shanghai Tongji Hospital of Tongji University, Shanghai, China.

Xuefeng Jiang (X)

Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Jingping Zhao (J)

Mental Health Institute of the Second Xiangya Hospital, Central South University, Changsha, China.

Xiaoxin Yang (X)

Editorial Office, Chinese Journal of Psychiatry, Beijing, China.

Mingyuan Zhang (M)

Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Xiangqun Wang (X)

Beijing Mental Health Institute, Peking University, Beijing, China.

Gang Wang (G)

Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.

Fude Yang (F)

Beijing HuiLongGuan Hospital, Peking University, Beijing, China.

Jian Hu (J)

Department of Psychiatry, The First Affiliated Hospital of Harbin Medical Universtiy, Harbin, China.

Xinjun Zhang (X)

Department of Psychiatry, Tianjing Anding Hospital, Tianjin, China.

Lingyang Du (L)

Department of Psychiatry, Xiaoshan Hospital of Zhejiang Province, Hangzhou, China.

Huichun Li (H)

Department of Psychiatry, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Bing Feng (B)

Department of Psychiatry, Tongde Hospital of Zhejiang Province, Hangzhou, China.

Zhenyu Hu (Z)

Department of Psychiatry, Ningbo Kangning Hospital, Ningbo, China.

Zuoming Chen (Z)

Department of Psychiatry, The Second Affiliated Hospital of Xinxiang Medical College, Xinxiang, China.

Chunxia Wang (C)

Department of Psychiatry, Qingdao Mental Health Center, Qingdao Seventh People's Hospital, Qingdao, China.

Xilin Wang (X)

Department of Psychiatry, Guangzhou Psychiatric Hospital, Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China.

Jinbei Zhang (J)

The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Tiebang Liu (T)

Department of Psychiatry, Shenzhen Kangning Hospital, Shenzhen, China.

Fujun Jia (F)

Department of Psychiatry, Guangdong Mental Health Centre, Guangzhou Medical University, Foshan, China.

Xueli Sun (X)

Department of Psychiatry, West China Hospital, Sichuan University, Chengdu, China.

Xiufeng Xu (X)

Department of Psychiatry, First Affiliated Hospital of Kunming Medical University, Kunming, China.

Huaqing Meng (H)

Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Gaohua Wang (G)

Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.

Ning Zhang (N)

Department of Clinical Psychology, Nanjing Brain Hospital, Nanjing Medical University, Nanjing, China.

Qiyi Mei (Q)

Department of Psychiatry, Suzhou Guangji Hospital, Suzhou, China.

Qingrong Tan (Q)

Department of Psychiatry, Xijing Hospital, Xi'an, China.

Chunqing Peng (C)

Department of Psychiatry, The First Affiliated Hospital of University of South China, Hengyang, China.

Jing Li (J)

Department of Psychiatry, Xiangya Hospital Central South University, Changsha, China.

Zheng Lu (Z)

Department of Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Department of Psychiatry, Shanghai Tongji Hospital of Tongji University, Shanghai, China.
ORCID: 0000-0001-7166-7898

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Classifications MeSH

questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Soins aux patients › Hospitalisation › Clinical characteristics of familial schizophrenia.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Clinical characteristics of familial schizophrenia.
questionsmedicales.fr › Troubles mentaux › Schizophrénie et troubles avec traits psychotiques › Troubles psychotiques › Clinical characteristics of familial schizophrenia.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Clinical characteristics of familial schizophrenia.
questionsmedicales.fr › Troubles mentaux › Schizophrénie et troubles avec traits psychotiques › Schizophrénie › Clinical characteristics of familial schizophrenia.