Early palliative care in haematological patients: a systematic literature review.


Journal

BMJ supportive & palliative care
ISSN: 2045-4368
Titre abrégé: BMJ Support Palliat Care
Pays: England
ID NLM: 101565123

Informations de publication

Date de publication:
Dec 2020
Historique:
received: 30 04 2020
revised: 24 08 2020
accepted: 04 09 2020
pubmed: 16 10 2020
medline: 6 3 2021
entrez: 15 10 2020
Statut: ppublish

Résumé

Early palliative care together with standard haematological care for advanced patients is needed worldwide. Little is known about its effect. The aim of the review is to synthesise the evidence on the impact of early palliative care on haematologic cancer patients' quality of life and resource use. A systematic review was conducted. The search terms were early palliative care or simultaneous or integrated or concurrent care and haematological or oncohaematological patients. The following databases were searched: PubMed, Embase, Cochrane, CINHAL and Scopus. Additional studies were identified through cross-checking the reference articles. Studies were in the English language, with no restriction for years. Two researchers independently reviewed the titles and abstracts, and one author assessed full articles for eligibility. A total of 296 studies titles were reviewed. Eight articles were included in the synthesis of the results, two controlled studies provided data on the comparative efficacy of PC interventions, and six one-arm studies were included. Since data pooling and meta-analysis were not possible, only a narrative synthesis of the study results was performed. The quality of the two included comparative studies was low overall. The quality of the six non-comparative studies was high overall, without the possibility of linking the observed results to the implemented interventions. Studies on early palliative care and patients with haematological cancer are scarce and have not been prospectively designed. More research on the specific population target, type and timing of palliative care intervention and standardisation of collected outcomes is required. CRD42020141322.

Sections du résumé

BACKGROUND BACKGROUND
Early palliative care together with standard haematological care for advanced patients is needed worldwide. Little is known about its effect. The aim of the review is to synthesise the evidence on the impact of early palliative care on haematologic cancer patients' quality of life and resource use.
PATIENTS AND METHODS METHODS
A systematic review was conducted. The search terms were early palliative care or simultaneous or integrated or concurrent care and haematological or oncohaematological patients. The following databases were searched: PubMed, Embase, Cochrane, CINHAL and Scopus. Additional studies were identified through cross-checking the reference articles. Studies were in the English language, with no restriction for years. Two researchers independently reviewed the titles and abstracts, and one author assessed full articles for eligibility.
RESULTS RESULTS
A total of 296 studies titles were reviewed. Eight articles were included in the synthesis of the results, two controlled studies provided data on the comparative efficacy of PC interventions, and six one-arm studies were included. Since data pooling and meta-analysis were not possible, only a narrative synthesis of the study results was performed. The quality of the two included comparative studies was low overall. The quality of the six non-comparative studies was high overall, without the possibility of linking the observed results to the implemented interventions.
CONCLUSIONS CONCLUSIONS
Studies on early palliative care and patients with haematological cancer are scarce and have not been prospectively designed. More research on the specific population target, type and timing of palliative care intervention and standardisation of collected outcomes is required.
PROSPERO REGISTRATION NUMBER UNASSIGNED
CRD42020141322.

Identifiants

pubmed: 33055091
pii: bmjspcare-2020-002386
doi: 10.1136/bmjspcare-2020-002386
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

395-403

Informations de copyright

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Silvia Tanzi (S)

Palliative Care Unit, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy silvia.tanzi@ausl.re.it.
Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy.

Francesco Venturelli (F)

Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy.
Epidemiology Unit, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy.

Stefano Luminari (S)

Hematologic Department, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy.

Franco Domenico Merlo (FD)

Scientific Department, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy.

Luca Braglia (L)

Department Infrastructure Research and Statistics Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy.

Chiara Bassi (C)

Medical Library, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy.

Massimo Costantini (M)

Scientific Department, Azienda USL-IRCCS Reggio Emilia, Reggio Emilia, Italy.

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Classifications MeSH